Sera
Cayman Chemical 6-MethylpterIn 100mg
A derivative of folic acid; generates singlet oxygen and hydrogen peroxide when exposed to photoirradiation in cell-free assays; has been used as an internal standard for the detection of pterins in urine
Cayman Chemical NCbzGlyProGlyGlyProAla 50mg
A peptide collagenase substrate; has been used to characterize the collagenolytic activity of bacterial collagenases in cell-free assays
Cayman Chemical UDPaDGalactosesodIM sal 50mg
A nucleotide sugar; an agonist of the purinergic P2Y14 receptor (EC50 = 0.67 µM); red blood cell levels are decreased in patients with PKU and maple syrup urine disease
Cayman Chemical MIlbemycIn oxIme 50mg
A semisynthetic macrocyclic lactone prepared by the oxidation and oximation of an 80:20 ratio of milbemycin A3 and A4; nematocide and insecticide activity via the potentiation of glutamate and GABA-gated chloride-channel opening
Cayman Chemical CytarabIn 5-monphosphate 50mg
An active metabolite of cytarabine; is incorporated into DNA by DNA polymerase α, which slows the rate of DNA synthesis by approximately 2000-fold in a cell-free assay; inhibits nuclear and mitochondrial DNA replication in S. cerevisiae at 15 mM; improves survival in an L1210 murine leukemia model at 3.5-75.1 mg/kg
Cayman Chemical AprIcItabIn 50mg
A nucleoside reverse transcriptase inhibitor; reduces HIV-1 infectivity in MT-4 and U937 cells (IC50s = 2.8 and 0.4 µM, respectively), as well as in isolated human CBMCs (IC50 = 0.4 µM)
Cayman Chemical -Indoxacarb 50mg
A broad-spectrum insecticide; topical adminstration is lethal to various insects (LD50s = 0.03->7.8 ng/mg); suppresses voltage-gated sodium channel currents in rat dorsal root ganglion neurons in a concentration-dependent manner
Cayman Chemical ArachIdIc AcIdodIum salt 100mg
A long-chain saturated fatty acid; inhibits fMLP-induced rabbit neutrophil aggregation at 5 μM
Cayman Chemical Longspur epmdum Epmedn B 50mg
A flavonoid glycoside; scavenges DPPH radicals in a cell-free assay (IC50 = 107.9 µM); increases proliferation of UMR-106 osteoblasts by 24.9 and 36.3% at 10 and 100 µM, respectively; prevents prednisolone-induced osteoporosis in zebrafish at 1 µM; inhibits TPA-induced EAr edema in mice (ED50 = 114 nmol/ear)
Cayman Chemical DaHydroxyglutarIc AcIdod 100mg
An α-hydroxy acid; decreases the OCR and ratio of ATP to ADP in U87 cells at 800 µM; increases the levels of TBARS in isolated rat cerebral cortex homogenates at 100 µM; urinary levels are increased in D-2-hydroxyglutaric aciduria, a neurometabolic disease characterized by epilepsy, muscle hypotonia, and delays in psychomotor development; structurally similar to α-ketoglutarate and competitively inhibits α-ketoglutarate-dependent dioxygenases, including histone lysine demethylases and DNA hydroxylases
Cayman Chemical 2 3DImethylmethcathInonhy 50mg
A potential designer drug that is structurally related to 4-MMC; intended for research and forensic applications
Cayman Chemical Fraxinellone 50mg
A liminoid degradant; has antifeedant activity against, and inhibits development of, armyworm larvae when applied to fresh wheat leaves at 5, 10, or 20 mg/ml; reduces LPS-induced nuclear translocation of the NF-κB subunit p65, as well as inhibits LPS-induced production of NO and PGE2 in RAW 264.7 cells; reduces tumor growth in an A549 mouse xenograft model at 30 or 100 mg/kg
Cayman Chemical 7-MethylgunosIn 100mg
A methylated form of guanosine; an RNA modification that is present in the 5’-terminal cap of mRNA, as well as in tRNA; has been used as a substrate to measure the activity of PNP; urinary levels are decreased in patients with prostate cancer