Sera
Cayman Chemical MaduramIcInamonIum salt 100mg
A polyether ionophore antibiotic; selectively binds to monovalent cations over divalent cations; active against Gram-positive bacteria (MICs = 0.9-125 UG/ml); reduces the viability of asexual and gametocyte P. falciparum parasites (EC50s = 1.3 and 14.8 nM, respectively); reduces P. berghei transmission in a mouse model of malaria at 4 and 8 mg/kg; reduces the severity of lesions and completely protects chicks against mortality in a model of E. tenella-induced coccidiosis at 5-10 ppm in the diet
Cayman Chemical ZuclopenthIxol 100mg
A dopamine receptor antagonist (Kis = 9.8 and 1.5 nM for D1 and D2 receptors, respectively); binds to 5-HT2 and 5-HT6, α1-adrenergic, and histamine receptors (Kis = 7.6, 3, 33, and 169 nM, respectively); inhibits dopamine-induced accumulation of cAMP in rat striatal homogenates (IC50 = 330 nM; Ki = 16 nM); decreases stereotypic behavior induced by methylphenidate in mice (ED50 = 0.8 µmol/kg); decreases stereotypic behavior induced by apomorphine in rats and dogs (ED50s = 6.0 and 1.3 µmol/kg, respectively); enhances memory retrieval in rats in an inhibitory avoidance task at 0.7 and 1.4 mg/kg, i.p.
Cayman Chemical FerroprotoporphyrIn 50mg
An iron-containing cofactor; involved the transport or storage of oxygen by hemoglobin or myoglobin, respectively, electron transfer by cytochrome b5, and oxidation of xenobiotics or endogenous substrates by CYPs
Cayman Chemical 3Methylbuphedronhydrochlo 50mg
A methylated analog of buphedrone; intended for forensic and research applications
Cayman Chemical PInacIdIlhydrate 50mg
A potassium channel opener, activating the ATP-modulated potassium channels of guinea pig bladder and heart with Ki values of 104 and 251 nM, respectively; completely relaxes coronary artery rings preconstricted with serotonin (IC50 = 1.26 µM)
Cayman Chemical DarunavIrethnolate 50mg
An HIV-1 protease inhibitor; active against HIV-1LAI in MT-2 cells (IC50 = 3 nM) (CC50 = 74.4 μM); active against wild-type and multidrug-resistant clinical isolates of HIV-1 in PHA-PBMCs (IC50s = 3 and 3-29 nM, respectively); inhibits cell-free diffusion and cell-to-cell spread of HIV-1 in Jurkat cell populations (IC50s = 2.5 and 2.8 nM, respectively)
Cayman Chemical 4MethylpentnoIc AcIdd12 100mg
An internal standard for the quantification of 4-methylpentanoic acid by GC- or LC-MS
Cayman Chemical 2DeoxycytIdIn5OtrIphos 100mg
A nucleoside triphosphate; has commonly been used in PCR reaction mixtures as a substrate for DNA synthesis by DNA polymerases
Cayman Chemical BetazolehydrochlorIde 50mg
A histamine H2 receptor agonist; induces acid secretion in isolated human gastric glands (EC50 = 120 µM); increases pepsin and acid levels in gastric juice in dogs at 3-10 mg/kg
Cayman Chemical trns-ZeatIn 100mg
A cytokinin plant growth regulator; binds to AHK3 (KD = 1.3 nM); increases chlorophyll levels in etiolated Cucumus sativus cotyledons in a concentration-dependent manner; increases callus growth and shoot formation in N. tabacum calluses at 5 and 50 µM; reduces production of ROS induced by Aβ25-35 in PC12 cells at 25-100 µM; scopolamine-induced spontaneous alternations in the Y-maze, indicating enhanced spatial memory, in mice at 1.5, 3, and 4.5 mg/kg per day
Cayman Chemical SIKVAVacetate 100mg
A laminin α1-derived peptide; binds to α3, α6, and β1 integrins; induces adhesion of CAC2 adenoid cystic carcinoma cells at 1 UG/ml; stimulates the proliferation, migration, and secretion of EGF, VEGF, TGF-β, and FGF in primary mouse fibroblasts at 100 UG/ml; topical administration of a chitosan hydrogel containing SIKVAV promotes wound healing and angiogenesis in mice
Cayman Chemical 3 4mthylendIoypropIopheno 50mg
An analytical reference standard categorized as a precursor in the synthesis of cathinones; intended for research and forensic applications
Cayman Chemical LarIxyl Acetate 50mg
A diterpenoid; inhibits the activity of TRPC6 (IC50 = 0.58 µM receptor) and is selective for TRPC6 over TRPC3 (IC50 = 6.83 µM), as well as over nine additional TRP channels at 10 µM; reduces mechanical and cold allodynia in a rat model of neuropathic pain induced by SNI
Cayman Chemical FenoterolhydrobromIde 50mg
An analytical reference standard categorized as a β2-adrenergic receptor agonist; has been used as a performance-enhancing drug in sports doping and is banned by WADA; intended for research and forensic applications