Human Sera
Cayman Chemical Ocmene 50mg
A cell-permeable benzoxazolo-sulfonamide compound that blocks human FBPase-1 enzymatic activity by competing at the AMP allosteric binding site (IC50 3 4 UM Ki 1 1 UM) blocks glucose production in starved rat hepatoma cells (IC50 6 6 UM)
Cayman Chemical GluLeu 50mg
An analytical reference standard that is structurally similar to known phytocannabinoids has been found in Cannabis intended for research and forensic applications
Cayman Chemical CItrulInated Hsp70R357 Po 1ea
Immunogen Diglycine-modified histone peptide Host Mouse Species Reactivity Species independent Cross Reactivity ( ) Diglycyl-modified lysine (-) Unmodified lysine Applications IP and WB
Cayman Chemical Josamycn 50mg
A peptide agonist of CaSR selective for CaSR over a panel of 33 receptors and ion channels as well as the norepinephrine transporter at 10 UM increases intracellular calcium levels in HEK293T cells expressing the human CaSR receptor (EC50 0 53 UM) inhibits parathyroid secretion from primary rat parathyroid cells (EC50 0 36 UM in the presence of calcium) decreases parathyroid hormone and calcium in plasma and serum respectively in a model of chronic renal insufficiency with secondary hyperthyroidism in nephrectomized rats fed high-phosphorus diet at 0 3 1 and 3 mg/kg
Cayman Chemical Fluprostenol Lacton DIol 50mg
A building block has been used in the synthesis of drUG-linker molecules for ADCs
Cayman Chemical Lndane 100mg
A DNA alkylating agent active metabolite of dacarbazine (DTIC) active degradation product of temozolomide cytotoxic to L-cells and decreases thymidine and uridine uptake by 55 and 65 respectively at 1 mM cytotoxic to TLX5 murine lymphoma cells induces formation of mammary adenofibromas in rats when administered at a cumulative dose of 890 mg per animal over 14 weeks
Cayman Chemical Ocmene 100mg
A reversible selective allosteric antagonist of mGluR7 that blocks agonist-induced calcium mobilization (IC50 26 nM)