Human Sera
Seracare Life Sciences Inc 5% HUMAN SERUM DIAGNOSTIC 1L
5% human serum albumin solution derived from human plasma obtained in FDA-licensed facilities. Suitable for use in cell culture applications.
Cayman Chemical Astoloca mnsuns Astolon 50mg
A sesquiterpene with anticancer activity; cytotoxic to H460, ES-2, and DU145 cells (IC50s = 51.3, 61.5, and 58 UG/ml, respectively)
Cayman Chemical Naloxegoloxalate 50mg
A peripherally acting antagonist of the μ-opioid receptor (Ki = 7.42 nM; pA2 = 7.95); selective for the μ-opioid receptor over the δ-opioid receptor (Ki = 866 nM); acts as a partial agonist of κ-opioid receptors in vitro (EC50 = 47 nM for [35S]GTPγS binding); reverses morphine-induced decreases in gastrointestinal motility and analgesia in a hot-plate assay in rats (ED50s = 23.1 and 55.4 mg/kg, respectively); exhibits minimal brain uptake in a rat brain perfusion model
Cayman Chemical AcetylDLcarnItInchlorIde 100mg
A racemic mixture of acetyl-D-carnitine and acetyl-L-carnitine; increases the oxidation rate of the branched-chain 2-oxo acid 3-methyl-2-butanoate in isolated rat muscle mitochondria in the absence of carnitine at 1 mM; decreases the hind limb vasculature blood flow rate in rats; decreases the levels of palmitic acid and oleic acid in the cerebral cortex during the recovery period in a dog model of insulin-induced hypoglycemic brain injury
Cayman Chemical nglca pubscns Subrosn 50mg
A prenylated coumarin with diverse biological activities; inhibits arachidonic acid-, collagen-, PAF-, ADP-, or U-46619-induced aggregation of washed isolated rabbit platelets (IC50s = 60, 132, 200, 234, and 200 µM, respectively); reduces arachidonic acid-induced TXB2 formation in the same model; inhibits PHA-induced NF-κB nuclear translocation in, as well as proliferation of, human PBMCs at 100 µM
Cayman Chemical Mn III ProtprphyrIn I Chl 50mg
A metalloporphyrin; induces mRNA expression of the genes encoding δ-aminolevulinate synthase and HO in chick embryo liver cells at 10 µM; manganese(III) protoporphyrin IX chloride-containing nanobialys have been used in MRI of fibrin clots in vitro; has been used in the synthesis of MnGGH
Cayman Chemical 6Chloro3IndolylDGlucur 100mg
A β-glucuronidase chromogenic substrate; upon cleavage by β-glucuronidase, an insoluble salmon precipitate is formed that can be used in histochemical analysis of β-glucuronidase activity
Cayman Chemical trns-ZeatIn RIbosIde 100mg
A cytokinin; suppresses hypocotyl adventitious root formation in cucumber plants from 0.001-1 µM; increases the activity of SOD, APX, CAT, and POD in the leaves, as well as improves turf quality and delays leaf wilting in a creeping bentgrass model of drought stress at 10 µM
Cayman Chemical CarteololhydrochlorIde 50mg
A β-adrenergic receptor antagonist (Kd = 13 nM); blocks isoproterenol-induced increases in heart rate, contractile force, and blood pressure in vagotomized dogs (ED50s = 2.3, 3.1, and 1.8 UG/kg, respectively); the (R) and (S)-enantiomers EAch reduce intraocular pressure in rabbits (1% solution)
Cayman Chemical AcamprosatecalcIum salt 100mg
An NMDA modulator with antagonist or agonist effects depending on brain region, receptor composition, and other factors; an acetylated derivative of homotaurine; decreases paired-pulse inhibition of GABAA IPSCs, indicating that it may inhibit GABAB autoreceptor-mediated inhibition of GABA release (300 µM); reduces voluntary intake of ethanol in rats (0.26 and 0.52 mmol/kg per day, i.p.)
Cayman Chemical EmtrIcItabIn 100mg
An antiviral nucleoside analog; an inhibitor of HIV-1 and hepatitis B reverse transcriptase; inhibits replication of HIV-1 (EC50s = 10-20 nM) and hepatitis B (EC50s = 10-40 nM) in various cell lines; inhibits duck hepatitis B viral DNA synthesis when administered pre- and post-viral inoculation in primary duck hepatocytes; reduces viremia and hepatic WHV replication in a dose-dependent manner in a woodchuck model of chronic WHV infection
Cayman Chemical 7 DIethylamInocoumarIn3ca 50mg
A fluorescent probe; has been used as a FRET acceptor conjugated to neomycin B or tobramycin for use in the analysis of bacterial RNA binding; has been used as a reactive probe for the derivatization of sulfonamides for LIF detection; ex/em = 407/472 nm, respectively
Cayman Chemical Coydals ynusuo Coydaln 50mg
An alkaloid with diverse biological activities; inhibits AChE (IC50 = 15 μM); nematocidal against S. ratti and S. venezuelensis third instar larvae (PC50s = 18 and 30 μM, respectively); inhibits thrombin-induced platelet aggregation in vitro (IC50 = 54.16 μg/ml); increases gastric emptying in rat models of apomorphine- and laparotomy-induced delayed gastric emptying at 1 and 3 mg/kg
Cayman Chemical TrIamcInolon 50mg
A synthetic glucocorticoid; increases expression of the calcitonin receptor in in murine osteoclast-like cells at 1 μM; reduces heat hyperalgesia and mechano-allodynia and decreases the number of TNF-α-positive mast cells in injured sciatic nerve in a rat model of chronic constriction injury-induced neuropathic pain at 3 mg/kg, s.c.; reduces levels of the glycosaminoglycans hyaluronic acid and chondroitin-4-sulfate in human keloid implants in athymic nude mice
Cayman Chemical 5-DeoxyadenosIn 50mg
An adenosine analog; an intermediate in the degradation of S-adenosyl-L-methionine; has been used in the study of enzyme kinetics, including those of phosphomethylpyrimidine synthase, glutamate mutase, and 5’-methylthioadenosine phosphorylase