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Antibody Production and Purification Reagents and Kits
Chemical reagents and kits designed for use in the production and/or purification of specific antibodies; includes substrates, inactivation reagents, standard controls, prepacked columns, purification kits, etc.
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A selective TRPA1 blocker that antagonizes TRPA1-mediated calcium influx induced by allyl isothiocyanate and 4-hydroxy nonenal (IC50s = 14.3 and 18.7 μM, respectively); 30 mg/kg twice daily in rats attenuates pain-related behavior in models of diabetic hypersensitivity and postoperative pain
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Three dye options gives you more ways to measure cell death.No wash protocol just add and read for fast easily automated workflow.Multiplex with other IntelliCyt kits like Cell Cycle for richer content.PrincipleThe Cell Membrane Integrity dyes are fluorescent molecules that are cell impermeant. Healthy cells with intact cell membranes will exclude the dyes. Unhealthy cells with compromised membranes will allow entry of the dye into the intracellular space. Upon entry to the cell the dye localizes to the nucleus and binds to DNA by intercalation.
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No wash protocol- fast easy antibody-labeling method optimal for screening antibody internalizationHigh throughput evaluation of antibody internalization- Assay designed to measure internalization of a large number of antibodies in 96- and 384-well plate formats using 20 L of cells and antibody.Cell viability can also be measured by multiplexing iQue Cell Membrane Integrity Dye to assess general cell health and antibody function.Cell specificity can be characterized by multiplexing iQue Encoding dyes cell lines or directly conjugated fluorescent antibodies cells .The Qbeads Assay can also be multiplexed to perform more detailed antibody assessments on the sample such as cytokine release.Available in Human and Mouse formats
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