Primary Antibody Matched Pairs
Biotium Granzyme B (NK/T-Cell Lymphoma Marker)(GZMB/3055), Biotin conjugate, 0.1mg/mL
Granzyme B is a member of the granule serine protease family stored specifically in NK cells or cytotoxic T cells. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. Granzyme B is crucial for the rapid induction of target cell apoptosis by CTLs in the cell-mediated immune response. Granzyme B is useful as a marker in the identification of NK/T-cell lymphomas. High percentages of cytotoxic T-cells have been shown to be an unfavorable prognostic indicator in Hodgkin's Disease. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommende
AdipoGen RBP4 rat rec
Protein. Rat RBP4 aa 19-201 is fused at the N-terminus to a FLAG -tag. Source HEK 293 cells. Endotoxin content <0.1EU/µg purified protein LAL test Lonza. Liquid. 0.2µm-filtered solution in PBS, pH 7.2. Purity >90% SDS-PAGE. Retinol binding protein 4 RBP4 RBP is a 21kDa secreted protein, a member of the lipocalin family and is known as the primary transporter of retinol vitamin A to tissues. A recent report revealed RBP4 as an adipokine linking glucose transporter 4 GLUT4 suppression in adipose tissue to insulin. Elevated human and mouse serum RBP4 levels are associated with insulin resistance and its severity, obesity, and certain components of metabolic syndrome. Furthermore, human serum RBP4 levels are closely related to renal function.
ABclonal Technology Mesothelin Rabbit mAb
This gene encodes a preproprotein that is proteolytically processed to generate two protein products megakaryocyte potentiating factor and mesothelin Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein This protein is overexpressed in epithelial mesotheliomas ovarian cancers and in specific squamous cell carcinomas Alternative splicing results in multiple transcript variants at least one of which encodes an isoform that is proteolytically processed
ABclonal Technology Phospho-CREB1-S129 Rabbit pAb
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms.
ABclonal Technology S100A7/Psoriasin Rabbit mAb
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs S100 proteins are localized in the cytoplasm and or nucleus of a wide range of cells and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation S100 genes include at least 13 members which are located as a cluster on chromosome 1q21 This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus The protein is overexpressed in hyperproliferative skin diseases exhibits antimicrobial activities against bacteria and induces immunomodulatory activities
ABclonal Technology OLR1 Rabbit pAb
This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimers disease. Alternate splicing results in multiple transcript variants.
ABclonal Technology ABflo 647 Rabbit anti- S100A9
Predicted to enable calcium ion binding activity and calcium-dependent protein binding activity Involved in peptidyl-cysteine S-nitrosylation positive regulation of blood coagulation and regulation of translation Acts upstream of or within several processes including actin cytoskeleton reorganization astrocyte development and regulation of integrin biosynthetic process Predicted to be located in cell junction cytosol and nucleoplasm Predicted to be active in cytoplasm extracellular space and nucleus Is expressed in several structures including jaw liver otic capsule skeleton and spleen red pulp Human ortholog(s) of this gene implicated in myocarditis Orthologous to human S100A9 (S100 calcium binding protein A9)
ABclonal Technology CGREF1 Rabbit pAb
Predicted to enable calcium ion binding activity. Predicted to be involved in negative regulation of cell population proliferation. Predicted to be located in extracellular region.
ABclonal Technology CD209 Rabbit pAb
This gene encodes a C-type lectin involved in cell adhesion and pathogen recognition. It recognizes a wide range of pathogens, including mycobacteria causing leprosy and tuberculosis, viruses like Ebola, hepatitis C, HIV-1, Dengue, and SARS-CoV. The protein has four domains: a carbohydrate recognition domain, a flexible neck domain, a transmembrane region, and a cytoplasmic domain for internalization. It is closely related to CLEC4M (L-SIGN), differing in viral recognition and expression. This gene is highly expressed on dendritic cells. Polymorphisms in the neck region are linked to HIV-1 protection, and SNPs in the promoter affect susceptibility and severity of infectious diseases, such as the rs4804803 SNP associated with SARS severity.
Human SOD1 ELISA Pair Set 5PP (Sino Biological)
Each vial contains 180 ng of recombinant SOD1. Reconstitute with 1 mL dilution buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A seven-point standard curve using 2-fold serial dilutions in dilution buffer, and a high standard of 4 ng/mL is recommended.
Human TNFRSF18 Protein 20ug (Sino Biological)
A DNA sequence encoding the Human TNFRSF18 (NP_683700.1) (Met1-Glu161) was expressed with a C-terminal polyhistidine tag followed by an AVI tag. The expressed protein was biotinylated in vivo by the Biotin-Protein ligase (BirA enzyme) which is co-expressed.
ABclonal Technology KLF8 Rabbit pAb
This gene encodes a protein which is a member of the Sp/KLF family of transcription factors. Members of this family contain a C-terminal DNA-binding domain with three Kruppel-like zinc fingers. The encoded protein is thought to play an important role in the regulation of epithelial to mesenchymal transition, a process which occurs normally during development but also during metastasis. A pseudogene has been identified on chromosome 16. Alternative splicing results in multiple transcript variants.
Meso Scale Discovery U-PLEX Human IP-10 Antibody Set, 5 Plate Size
U-PLEX Human IP-10 Antibody Set (5 Plate Size)
