Primary Antibody Matched Pairs
Human GLA ELISA Pair Set 5PP (Sino Biological)
Each vial contains 455 ng of recombinant Human alpha-Galactosidase A / GLA. Reconstitute with 1 mL dilution buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A seven-point standard curve using 2-fold serial dilutions in dilution buffer, and a high standard of 13000 pg/mL is recommended.
ABclonal Technology NUP98 Rabbit pAb
This gene belongs to the nucleoporin family and encodes a 186 kDa precursor protein that undergoes autoproteolytic cleavage to produce 98 kDa and 96 kDa nucleoporins. The 98 kDa nucleoporin, containing a Gly-Leu-Phe-Gly (GLGF) repeat, is involved in nuclear import, export, mitotic progression, and gene expression regulation. The 96 kDa nucleoporin is a scaffold component of the nuclear pore complex (NPC). Proteolytic cleavage is essential for targeting these proteins to the NPC. Translocations of this gene with other genes have been observed in leukemias, resulting in chimeras with the GLGF domain fused to the partner genes C-terminus. Alternative splicing generates multiple transcript variants, including those lacking the 96 kDa nucleoporin region and those processed proteolytically.
Biotium MMP3 (Marker of Metastasis and Rheumatoid Arthritis)(MMP3/2806), CF568 conjugate, 0.1mg/mL
The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also designated stromelysin-1, 2 and 3, respectively) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes of
ABclonal Technology PE Rabbit anti- CD96/TACTILE
Acts upstream of or within negative regulation of interferon-gamma production negative regulation of natural killer cell cytokine production and response to lipopolysaccharide Predicted to be located in cytoplasm Is expressed in several structures including blood central nervous system ganglia heart and lung Human ortholog(s) of this gene implicated in C syndrome Orthologous to human CD96 (CD96 molecule)
Biotium Thymidylate Synthase (5-FU Resistance Marker) (TYMS/1884), CF647 conjugate, 0.1mg/mL
This antibody recognizes a protein of 36 kDa, identified as Thymidylate Synthase (TS) (EC 2.1.1.45). It converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. TS is also a critical target for the fluoropyrimidines, an important group of antineoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates TS by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate. Expression of TS protein has been reported to associate with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not r
Human IL10RB ELISA Pair Set 15PP (Sino Biological)
Each vial contains 110 ng of recombinant IL10RB. Reconstitute standard powder with 1 mL detection antibody dilution buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A seven-point standard curve usi ng 2-fold serial dilutions in sample dilution buffer, and a high standard of 5000 pg/mL is recommended.
Sino Biological Human SerpinA3 / AACT Protein (His Tag), Endotoxin-Free 1mg
A DNA sequence encoding the human SERPINA3 (NP_001076.2) (Met 1-Ala 423) was expressed, with a C-terminal polyhistidine tag.
Miltenyi Biotec, Inc. CD79b-VioBright FITC, h, REA120, 100 t
Identification and enumeration of CD79b+ cells by flow cytometry.
This product is subject to the following: Miltenyi Biotec, Inc. Terms and Conditions of Sale For Products and Services
ABclonal Technology CD96 Rabbit mAb
CD96 (cluster of differentiation 96) belongs to the IgG (immunoglobulin) superfamily receptors It is expressed in the spinal cord kidney trachea digestive tissues prostate placenta bone of adults and fetal brain and liver This gene is located on human chromosome 3q13 The protein encoded by this gene belongs to the immunoglobulin superfamily It is a type I membrane protein The protein may play a role in the adhesive interactions of activated T and NK cells during the late phase of the immune response It may also function in antigen presentation Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified
Biotium MMP3 (Marker of Metastasis and Rheumatoid Arthritis)(MMP3/2655), CF568 conjugate, 0.1mg/mL
The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also designated stromelysin-1, 2 and 3, respectively) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes of
Biotium RAD51 (Prognostic and Response to Chemotherapy Marker)(RAD51/2765), Biotin conjugate, 0.1mg/mL
RAD51 is one of the key factors of DNA repair by homologous recombination and has been shown to have anti-apoptotic activity in tumor cells. RAD51 protein interacts with a variety of tumor suppressor proteins including p53, BRCA1 and BRCA2. Elevated expression of RAD51 enhances radio-resistance of human tumor cells. Overexpression of RAD51 protein in tumor cells renders them resistant against cytotoxic drugs like Cisplatin. RAD51 interacts with BRCA1 and BRCA2 to influence subcellular localization and cellular response to DNA damage. BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis from deregulation of RAD51. High-level expression of RAD51 has been observed in a variety of human malignancies. RAD51 overexpression correlates with histological grading of the tumor in invasive ductal mammary carcinoma. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightnes
Biotium Annexin A1 / (Hairy Cell Leukemia Marker)(ANXA1/1671), CF488A conjugate, 0.1mg/mL
Annexin A1 belongs to the annexin family. It plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. In resting conditions Annexin A1 is localized to the cytoplasm. Upon activation it is mobilized to the membrane and secreted. Annexin A1 and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. Expression of the ANXA1 gene is upregulated in hairy cell leukemia (HCL). Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue
Biotium Prostate Specific Acid Phosphatase (PSAP) (ACPP/1339), CF647 conjugate, 0.1mg/mL
This antibody recognizes a protein of 52 kDa, identified as prostate specific acid phosphatase (PSAP). This enzyme catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. PSAP is found in non-neoplastic adult and fetal prostatic glands, primary and metastatic prostatic carcinomas. It shows no staining in granulocytes, osteoclasts, parietal cells of the stomach, liver cells, renal cell or breast carcinomas.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.