Mouse Secondary Antibodies
Biotium NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/294), CF568 conjugate, 0.1mg/mL
Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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Biolegend Ultra-LEAF Purified anti-human CD28H (TMIGD2) [W23119G] Isotype Rat IgG2a Reactivity Human Apps Block Size 1 mg
Ultra-LEAF Purified anti-human CD28H (TMIGD2) [W23119G] Isotype Rat IgG2a Reactivity Human Apps Block Size 1 mg
Cayman Chemical WIthaferIn A 10mg
A steroidal lactone with diverse biological activities; binds to and induces aggregation of vimentin intermediate filaments in cultured endothelial cells and fibroblasts, inducing apoptosis from 2-25 μM; induces formation of perinuclear aggregates in a variety of other intermediate filament networks; induces noncanonical ferroptosis via induction of lipid peroxidation through interaction with KEAP1 in IMR-32 neuroblastoma cells; binds to and inhibits GPX4 in IMR-32 cells; reduces intratumor GPX4 expression and induces tumor regression in an IMR-32 mouse xenograft model at 4 mg/kg; inhibits angiogenesis in a mouse model of injury-induced corneal neovascularization at 2 mg/kg
American Research Products Inc Human Fc gamma RIIIb / CD16b (NA2) protein 1MG
The sequence of the extracellular domain of human CD16b (Gly 17-Ser 200) was fused with a C-terminal tag consisting of the AVI tag, TEV protease recognition sequence and a 10-His tag. The full protein sequence can be downloaded from the product webpage.
Cayman Chemical PIfIthrIn-a 50mg
An inactivator of p53 that blocks p53-dependent transcriptional activation and apoptosis, preventing p53-mediated apoptosis by cytotoxic compounds in C8 cells at 10 μM and in human umbilical vein endothelial cells at 30 μM
Immunology Consultants anti-Human IgG Fc Antibody (Mouse Clone #907)
This monoclonal antibody provides sensitive, specific detection of the human IgG Fc region, supporting ELISA, Western blotting, and immunoassay development requiring Fc‑directed recognition. Clone 907 delivers strong affinity and low nonspecific binding, enabling accurate measurement of human IgG in serum, plasma, and purified antibody preparations. It is ideal for therapeutic antibody characterization, immunoassay calibration, and studies examining Fc‑mediated immune interactions. MGFC‑80A‑907 offers consistent lot‑to‑lot performance, ensuring reliable Fc detection across diverse analytical applications.
Cayman Chemical BortezomIb ImpurIty A 10mg
A metabolite of bortezomib; a degradation product of bortezomib formed under oxidative conditions
Cell Biologics Immortalized Mouse Primary Lymphatic Fibroblasts
Immortalized Mouse Primary Lymphatic Fibroblasts