Mouse Secondary Antibodies
Biotium MUC4 (Mucin 4 / Gastric Mucin)(MUC4/3105), CF488A conjugate, 0.1mg/mL
The major constituents of mucus, the viscous secretion that covers epithelial surfaces such as those in the trachea, colon, and cervix, are highly glycosylated proteins called mucins. These glycoproteins play important roles in the protection of the epithelial cells and have been implicated in epithelial renewal and differentiation. This gene encodes an integral membrane glycoprotein found on the cell surface, although secreted isoforms may exist. MUC-4 transcripts have been detected in normal respiratory epithelium and lung. MUC-4 is a very specific (100%) and sensitive (90%) marker of lung adenocarcinomas and is negative for mesotheliomas. Reportedly, MUC-4 expression in invasive ductal carcinoma of the pancreas is an independent factor for poor prognosis. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S an
Biotium CELA3B(CELA3B/1218), CF740 conjugate, 0.1mg/mL
This MAb recognizes a protein of ~17 kDa, identified as CELA3B (Chymotrypsin like elastase family member 3B). Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3B has little elastolytic activity. Like most of the human elastases, elastase 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein; it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays.Primary antibodie
Cayman Chemical Ciliobrevin A, Purity: ≥98%, CAS: 302803-72-1, 50 mg
A hedgehog pathway inhibitor that blocks Shh-induced hedgehog pathway activation (IC50 = 7 µM); inhibits primary cilia formation; inhibits dynein-dependent microtubial gliding and ATPase activities of the cytoplasmic AAA+ family; inhibits mTORC1 activity in uninfected and HCMV-infected cells
Glen Research 2'-Fluoro-ara-Adenosine Phosphoramidite, 0.5 g, C47H51FN7O7P
2'-Fluoro-ara-Adenosine Phosphoramidite, 0.5 g, C47H51FN7O7P
Cayman Chemical α-Ketoisocaproic Acid (sodium salt), Purity: ≥95%, CAS: 4502-00-5, 10 g
A metabolite of leucine catabolism; increases the production of reactive species and decreases the activity of mitochondrial complex I and complex II-III in the rat hippocampus at 4 µmol; urine levels are reduced in db/db diabetic mice compared with heterozygous db/m non-diabetic mice; accumulates in the tissues and body fluids of patients with maple syrup urine disease
Cayman Chemical α-Cyclodextrin (hydrate), Purity: ≥95%, CAS: 51211-51-9, 50 g
A cyclic hexasaccharide; forms inclusion complexes with wide variety of molecules, improving their solubility and stabilization; has commonly been used in the separation and purification of chemicals on an industrial scale; has also been used in the pharmaceutical and food industries
Cayman Chemical 1,3,6,8-Pyrenetetrasulfonic Acid (sodium salt hydrate), Purity: ≥95%, CAS: 1771776-02-3, 1 g
A synthetic intermediate; has been used to stabilize intermolecular interactions for the crystallization of L. mexicana pyruvate kinase
Cayman Chemical α-Ketoisocaproic Acid (sodium salt), Purity: ≥95%, CAS: 4502-00-5, 25 g
A metabolite of leucine catabolism; increases the production of reactive species and decreases the activity of mitochondrial complex I and complex II-III in the rat hippocampus at 4 µmol; urine levels are reduced in db/db diabetic mice compared with heterozygous db/m non-diabetic mice; accumulates in the tissues and body fluids of patients with maple syrup urine disease