Rabbit Secondary Antibodies
ABclonal Technology PE Rabbit anti-Mouse Ly-49D
Predicted to enable carbohydrate binding activity Predicted to act upstream of or within cell adhesion Located in external side of plasma membrane
ABclonal Technology PE Rabbit anti-Mouse Ly-49D
Predicted to enable carbohydrate binding activity Predicted to act upstream of or within cell adhesion Located in external side of plasma membrane
Jackson Immuno Research Labs Alexa Fluor 647-AffiniPure Rabbit Anti-Mouse IgG (H+L) (min X Hu Sr Prot)
Alexa Fluor 647-AffiniPure Rabbit Anti-Mouse IgG (H+L) (min X Hu Sr Prot)
Jackson Immuno Research Labs Cy3-AffiniPure Rabbit Anti-Mouse IgG + IgM (H+L)
Cy3-AffiniPure Rabbit Anti-Mouse IgG + IgM (H+L)
ABclonal Technology PE Rabbit anti-Mouse CD5 mAb
CD5 is a type I transmembrane protein belonging to the scavenger receptor cysteine-enriched (SRCR) family characterized by the presence of at least one SRCR domain containing 90-110 amino acids CD5 is expressed in all mature T cells B-1A subsets of mature B cells and certain leukemia B cells It is elevated in regulatory T and B cells (Tregs Bregs) CD5 expression was also elevated in incompetent T and B cells Elevated levels of CD5 have also been found in many autoimmune diseases CD5 binds to T cell receptors (TCR) and negatively regulates T cell activation and differentiation The expression of CD5 in tumor-infiltrating T lymphocytes was negatively correlated with their antitumor activity Recently it has been reported that CD5 binds directly to IL6 and mediates downstream signal transduction CD5 B cells promote tumor growth in animal models Agents targeting CD5 are being actively explored as therapeutic interventions for cancer and other conditions
ABclonal Technology PE Rabbit anti-Mouse CD62E mAb
Predicted to enable several functions including oligosaccharide binding activity phospholipase binding activity and sialic acid binding activity Involved in positive regulation of leukocyte tethering or rolling Acts upstream of or within positive regulation of leukocyte migration Predicted to be located in several cellular components including caveola clathrin-coated pit and perinuclear region of cytoplasm Predicted to be integral component of plasma membrane Predicted to be active in external side of plasma membrane and extracellular space Is expressed in several structures including adrenal gland genitourinary system incisor integumental system and limb segment Human ortholog(s) of this gene implicated in IgA glomerulonephritis brain ischemia cerebrovascular disease and coronary artery disease Orthologous to human SELE (selectin E)
ABclonal Technology APC Rabbit anti-Mouse TNF-a
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily Members of this family are classified based on primary sequence function and structure This protein is synthesized as a type-II transmembrane protein and is reported to be cleaved into products that exert distinct biological functions It plays an important role in the innate immune response as well as regulating homeostasis but is also implicated in diseases of chronic inflammation In mouse deficiency of this gene is associated with defects in response to bacterial infection with defects in forming organized follicular dendritic cell networks and germinal centers and with a lack of primary B cell follicles Alternative splicing results in multiple transcript variants
ABclonal Technology PE Rabbit anti-Mouse CD19 mAb
Involved in several processes including B-1 B cell differentiation positive regulation of phosphatidylinositol 3-kinase activity and positive regulation of release of sequestered calcium ion into cytosol Acts upstream of or within B cell receptor signaling pathway Located in external side of plasma membrane Is integral component of plasma membrane Is expressed in liver and spleen Human ortholog(s) of this gene implicated in common variable immunodeficiency Orthologous to human CD19 (CD19 molecule)
ABclonal Technology PE Rabbit anti-Mouse CD47 mAb
Predicted to enable protein binding activity involved in heterotypic cell-cell adhesion and thrombospondin receptor activity Involved in regulation of nitric oxide biosynthetic process Acts upstream of or within several processes including monocyte aggregation opsonization and positive regulation of phagocytosis Located in extracellular exosome Is integral component of plasma membrane Is expressed in several structures including alimentary system central nervous system genitourinary system hemolymphoid system gland and liver and biliary system Orthologous to human CD47 (CD47 molecule)
ABclonal Technology PE Rabbit anti-Mouse CD103 mAb
Predicted to enable metal ion binding activity Predicted to act upstream of or within cell adhesion and integrin-mediated signaling pathway Located in external side of plasma membrane Is expressed in several structures including alimentary system genitourinary system lymph node nasal septum and nucleus pulposus Orthologous to human ITGAE (integrin subunit alpha E)
ABclonal Technology APC Rabbit anti-Mouse CD19
Involved in several processes including B-1 B cell differentiation positive regulation of phosphatidylinositol 3-kinase activity and positive regulation of release of sequestered calcium ion into cytosol Acts upstream of or within B cell receptor signaling pathway Located in external side of plasma membrane Is integral component of plasma membrane Is expressed in liver and spleen Human ortholog(s) of this gene implicated in common variable immunodeficiency Orthologous to human CD19 (CD19 molecule)
ABclonal Technology APC Rabbit anti-Mouse CD19
Involved in several processes including B-1 B cell differentiation positive regulation of phosphatidylinositol 3-kinase activity and positive regulation of release of sequestered calcium ion into cytosol Acts upstream of or within B cell receptor signaling pathway Located in external side of plasma membrane Is integral component of plasma membrane Is expressed in liver and spleen Human ortholog(s) of this gene implicated in common variable immunodeficiency Orthologous to human CD19 (CD19 molecule)
Jackson Immuno Research Labs Fluorescein (FITC)-AffiniPure Rabbit Anti-Mouse IgM µ Chain Specific (min X Hu Sr Prot)
Fluorescein (FITC)-AffiniPure Rabbit Anti-Mouse IgM µ Chain Specific (min X Hu Sr Prot)
Jackson Immuno Research Labs Alexa Fluor 594-AffiniPure F(ab')2 Fragment Rabbit Anti-Mouse IgG F(ab')2 Fragment Specific (min X Hu Sr Prot)
Alexa Fluor 594-AffiniPure F(ab')2 Fragment Rabbit Anti-Mouse IgG F(ab')2 Fragment Specific (min X Hu Sr Prot)
ABclonal Technology PE Rabbit anti-Mouse CD56/NCAM
Predicted to enable LRR domain binding activity and phosphatase binding activity Involved in commissural neuron axon guidance and regulation of semaphorin-plexin signaling pathway Acts upstream of or within several processes including homotypic cell-cell adhesion positive regulation of calcium-mediated signaling and regulation of exocyst assembly Located in several cellular components including external side of plasma membrane growth cone and neuronal cell body Is expressed in several structures including embryo mesenchyme nervous system sensory organ skin and urinary system Human ortholog(s) of this gene implicated in bipolar disorder middle cerebral artery infarction and pancreatic cancer Orthologous to human NCAM1 (neural cell adhesion molecule 1)