Rabbit Secondary Antibodies
ABclonal Technology PE Rabbit anti-Human CR2/CD21
This gene encodes a membrane protein which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9) Alternatively spliced transcript variants encoding different isoforms have been found for this gene
ABclonal Technology PE Rabbit anti-Human CR2/CD21
This gene encodes a membrane protein which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9) Alternatively spliced transcript variants encoding different isoforms have been found for this gene
ABclonal Technology 594 Rabbit anti-Human SIGLEC9
Predicted to enable monosaccharide binding activity and sialic acid binding activity Predicted to be involved in cell adhesion Predicted to act upstream of or within negative regulation of inflammatory response and negative regulation of phagocytosis engulfment Predicted to be located in external side of plasma membrane Predicted to be active in plasma membrane
ABclonal Technology PE Rabbit anti-Human CD131 mAb
The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3 IL-5 and CSF Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP)
ABclonal Technology CDK1/2 Rabbit PolymAb
This gene encodes a member of a family of serine threonine protein kinases that participate in cell cycle regulation The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex which regulates progression through the cell cycle Activity of this protein is especially critical during the G1 to S phase transition This protein associates with and regulated by other subunits of the complex including cyclin A or E CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B) Alternative splicing results in multiple transcript variants
ABclonal Technology PE Rabbit anti-Mouse CD88/C5aR
Enables complement component C5a receptor activity Involved in several processes including astrocyte activation positive regulation of vascular endothelial growth factor production and regulation of granulocyte chemotaxis Acts upstream of or within defense response to Gram-positive bacterium neutrophil chemotaxis and response to peptidoglycan Predicted to be located in several cellular components including apical part of cell basolateral plasma membrane and cell surface Predicted to be active in plasma membrane Is expressed in several structures including brain liver neural ectoderm and sensory organ Orthologous to several human genes including OPRPN (opiorphin prepropeptide)
ABclonal Technology 594 Rabbit anti-Human CD131
The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3 IL-5 and CSF Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP)
ABclonal Technology 594 Rabbit anti-Human CD131
The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3 IL-5 and CSF Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP)
ABclonal Technology ABflo 647 Rabbit anti- CD48
Predicted to enable antigen binding activity and signaling receptor activity Acts upstream of or within T cell activation and signal transduction Located in external side of plasma membrane Is expressed in left lung liver right lung and thymus primordium Orthologous to human CD48 (CD48 molecule)
ABclonal Technology ABflo 594 Rabbit anti- CD48
Predicted to enable antigen binding activity and signaling receptor activity Acts upstream of or within T cell activation and signal transduction Located in external side of plasma membrane Is expressed in left lung liver right lung and thymus primordium Orthologous to human CD48 (CD48 molecule)
ABclonal Technology ABflo 488 Rabbit anti-Dog CD19
This gene encodes a cell surface protein from the immunoglobulin gene superfamily expressed mainly in B cell lymphocytes It serves as a marker for pre-B cells but is downregulated in antibody-secreting plasma cells The protein features two extracellular Ig-like domains a non-Ig-like domain a hydrophobic transmembrane region and a large C-terminal cytoplasmic domain It forms a complex with CD21 and CD81 reducing the activation threshold for B cells Activation of this complex triggers the phosphatidylinositol 3-kinase pathway and calcium ion release This protein is targeted by CAR T-cells in lymphoblastic leukemia treatment Mutations are linked to common variable immunodeficiency 3 (CVID3) causing B-cell differentiation failure hypogammaglobulinemia and recurrent infections Alternative splicing produces multiple isoforms
ABclonal Technology 488 Rabbit anti-Human CaSR
The protein encoded by this gene is a plasma membrane G protein-coupled receptor that senses small changes in circulating calcium concentration The encoded protein couples this information to intracellular signaling pathways that modify parathyroid hormone secretion or renal cation handling and thus this protein plays an essential role in maintaining mineral ion homeostasis Mutations in this gene are a cause of familial hypocalciuric hypercalcemia neonatal severe hyperparathyroidism and autosomal dominant hypocalcemia
ABclonal Technology PE Rabbit anti-Mouse Ly-49D
Predicted to enable carbohydrate binding activity Predicted to act upstream of or within cell adhesion Located in external side of plasma membrane
ABclonal Technology PE Rabbit anti-Mouse Ly-49D
Predicted to enable carbohydrate binding activity Predicted to act upstream of or within cell adhesion Located in external side of plasma membrane
ABclonal Technology ABflo 647 Rabbit anti- IgG1
Mouse IgG1 is a subtype of immunoglobulin G antibody that is produced by B cells in response to an antigen It is the most abundant IgG subtype in the serum and plays a crucial role in the adaptive immune response Mouse IgG1 is composed of two heavy chains and two light chains and it is involved in opsonization complement activation and antibody-dependent cell-mediated cytotoxicity It is also involved in the regulation of immune responses including the activation of T cells and the inhibition of B cell activation Mouse IgG1 is widely used in research and diagnostic applications including ELISA Western blotting and immunohistochemistry It is also used in therapeutic applications such as immunotherapy and vaccine development