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Filtered Search Results
Cayman Chemical p120CATnInCTerm RabbIt 100uL
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An MTH1 inhibitor (IC50 72 nM) selective for MTH1 over a panel of 456 kinases at 1 UM induces oxidative DNA damage and apoptosis in SGC-7901 and BGC-823 cancer cells at 30 UM induces ROS production and apoptosis in the same model inhibits proliferation in a panel of 14 cancer cell lines expressing wild-type or various mutant forms of K-Ras or p53 (IC50s 0.52-7.4 UM) inhibits tumor growth in an SW 480 mouse xenograft model at 25 mg/kg
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Immunoreagents Inc RABBIT A-MOUSE IGG ALP
Secondary Antibody; Rabbit anti-mouse IgG (H&L) - Affinity Pure, min x w/Human Serum Proteins, ALP Conjugate, Host: Rabbit, Format: Liq, Label: ALP, Applications: WB, ELISA
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Immunoreagents Inc RABBIT A-MOUSE IGG DYLIGHT650
Secondary Antibody; Rabbit anti-mouse IgG (H&L) - Affinity Pure, DyLight 650 Conjugate, Host: Rabbit, Format: Lyo, Label: DyL650, Applications: WB, ELISA, IHC/ICC, IF, IP, FC, FACS
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Cayman Chemical SynaptophysInCTRm RabbIt 100uL
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A DGK inhibitor (Ki 58 M) reduces basal and thrombin-stimulated phosphatidic acid levels in washed isolated human platelets at 30 100 and 500 M
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Cayman Chemical OX40CD134CTerm RabbIt Mo 100uL
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A catechol estrogen and minor metabolite of estrogen production is increased in microsomes prepared from human mammary adenocarcinoma and fibroadenoma microsomes compared with microsomes prepared from non-cancerous tissues induces renal tumor formation in male hamsters at 25 mg/animal
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ABclonal Technology MFI2 Rabbit mAb
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The protein encoded by this gene is a cell-surface glycoprotein found on melanoma cells The protein shares sequence similarity and iron-binding properties with members of the transferrin superfamily The importance of the iron binding function has not yet been identified This gene resides in the same region of chromosome 3 as members of the transferrin superfamily Alternative splicing results in two transcript variants
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United States Biological Corporation ANTI-C1QTNF1 NT RABBIT POLY AN
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NC3728128 ANTI-C1QTNF1 NT RABBIT POLY AN
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ABclonal Technology NDUFV1 Rabbit mAb
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The mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V) This gene encodes a 51 kDa subunit of the NADH ubiquinone oxidoreductase complex I a large complex with at least 45 nuclear and mitochondrial encoded subunits that liberates electrons from NADH and channels them to ubiquinone This subunit carries the NADH-binding site as well as flavin mononucleotide (FMN)- and Fe-S-biding sites Defects in complex I are a common cause of mitochondrial dysfunction a syndrome that occurs in approximately 1 in 10 000 live births Mitochondrial complex I deficiency is linked to myopathies encephalomyopathies and neurodegenerative disorders such as Parkinson s disease and Leigh syndrome Alternative splicing results in multiple transcript variants encoding distinct isoforms
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American Research Products Inc Rabbit MatriX Metalloproteinas
Rabbit MatriX Metalloproteinase 13 MMP-13 ELISA Kit from CUSABIO Detection Range 93 75 pg/mL-6000 pg/mL Sensitivity 23 44 pg/mL Sample serum plasma tissue homogenates Method Sandwich
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Cayman Chemical CR2CD21C-Term RabbIt Mon 100uL
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An adenosine A2A and A2B receptor dual antagonist inhibits the ability of adenosine to suppress activation of human CD4 or CD8 T cells as well as monocyte-derived dendritic cells in vitro reduces tumor growth in an AT3-OVA syngeneic mouse model alone or in combination with doxorubicin acts synergistically with an anti-PD-1 antibody to reduce tumor growth in a B16/F10 syngeneic mouse model
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Cayman Chemical p16INK4ACTerm RabbIt Mon 100uL
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A selective estrogen receptor covalent antagonist covalently modifies cysteine 530 in the ligand binding domain of wild-type ERa and ERaY537S inhibits expression of the ERa target genes GREB1 and TFF1 in MCF-7 cells overexpressing wild-type ERa (IC50s 2.74 and 1.3 nM respectively) ERaY537S (IC50s 29.38 and 19.4 nM respectively) ERaY537N (IC50s 8.14 and 6.1 nM respectively) ERaY537C (IC50s 12.19 and 9.5 nM respectively) or ERaD538G (IC50s 24.87 and 4 nM respectively) inhibits the growth of MCF-7 cells overexpressing wild-type ERa or ERaY537S (GI50s 1.3 and 8.3 nM respectively) reduces tumor growth in an MCF-7 mouse xenograft model and an ERaY537S/WT ST941 PDX mouse model in a dose-dependent manner
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Cayman Chemical IgG3humn RabbIt Monclona 100ug
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Immunogen: Human IgG3 • Host: Rabbit • Species Reactivity: (+) Human • Cross Reactivity: (-) Human IgG1, IgG2, IgG4, IgM, IgA, IgD, IgE; (-) Cynomolgus monkey, goat, mouse, rat, or rhesus monkey IgG • Applications: ELISA, ICC, IHC
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ABclonal Technology FKBP10 Rabbit mAb
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The protein encoded by this gene belongs to the FKBP-type peptidyl-prolyl cis trans isomerase (PPIase) family This protein localizes to the endoplasmic reticulum and acts as a molecular chaperone Alternatively spliced variants encoding different isoforms have been reported but their biological validity has not been determined
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Cayman Chemical PaxIlInaN-Term RabbIt 100uL
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A partial agonist of muscarinic acetylcholine receptors (Kis 5 1 5 0.2 and 7.6 UM for M1-5 receptors respectively in radioligand binding assays) induces contraction of isolated human umbilical veins (EC50 1.23 UM) intrathecal administration inhibits GNTI-induced compulsive hindlimb neck-scratching behavior in mice enhances spontaneous working memory in the Y maze in wild-type mice and reverses learning and memory impairments induced by bulbectomy in mice in a passive avoidance test
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Cell Signaling Technology CD89FCAR F1T9J Rabbit mAb 100 ul
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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CD89FCAR F1T9J Rabbit mAb 100 ul
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