Rabbit Secondary Antibodies
Jackson Immuno Research Labs Rhodamine (TRITC)-AffiniPure Rabbit Anti-Mouse IgG + IgM (H+L)
Rhodamine (TRITC)-AffiniPure Rabbit Anti-Mouse IgG + IgM (H+L)
ABclonal Technology PE Rabbit anti-Mouse IgG1 mAb
Mouse IgG1 is a subtype of immunoglobulin G antibody that is produced by B cells in response to an antigen It is the most abundant IgG subtype in the serum and plays a crucial role in the adaptive immune response Mouse IgG1 is composed of two heavy chains and two light chains and it is involved in opsonization complement activation and antibody-dependent cell-mediated cytotoxicity It is also involved in the regulation of immune responses including the activation of T cells and the inhibition of B cell activation Mouse IgG1 is widely used in research and diagnostic applications including ELISA Western blotting and immunohistochemistry It is also used in therapeutic applications such as immunotherapy and vaccine development
ABclonal Technology APC Rabbit anti-Mouse CD38 mAb
This gene encodes a non-lineage-restricted type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5 -diphosphate-ribose an intracellular calcium ion mobilizing messenger The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein This protein has an N-terminal cytoplasmic tail a single membrane-spanning domain and a C-terminal extracellular region with four N-glycosylation sites Knockout mice deficient for this gene display altered humoral immune responses In addition knockout mice exhibit higher locomotor activity and defects in nurturing and social behaviors
ABclonal Technology PE Rabbit anti-Mouse CD4 mAb
Predicted to enable several functions including interleukin-16 binding activity interleukin-16 receptor activity and protein homodimerization activity Involved in helper T cell enhancement of adaptive immune response Acts upstream of or within several processes including defense response to Gram-negative bacterium positive regulation of calcium-mediated signaling and positive regulation of peptidyl-tyrosine phosphorylation Located in endoplasmic reticulum external side of plasma membrane and membrane raft Is expressed in several structures including alimentary system brain genitourinary system hemolymphoid system and liver and biliary system Used to study type 1 diabetes mellitus Human ortholog(s) of this gene implicated in immunodeficiency 79 Orthologous to human CD4 (CD4 molecule)
ABclonal Technology PE Rabbit anti-Mouse CD94 mAb
CD94 is a 43 39 kD C-type lectin also known as Kp43 It is present on all NK cells NKT cells and a subset of CD8-positive T lymphocytes in most mouse strains CD94 is a type-II transmembrane protein with an extracellular lectin-like domain and a short cytoplasmic tail CD94 is expressed as a disulphide-linked heterodimer with a NKG2 subunit believed to mediate signal transduction When associated with NKG2A the complex triggers inhibition when associated with NKG2C the complex triggers stimulation The receptor complex of CD94 and NKG2 receptors bind to the ligand Qa-1 and are thought to play a role in maintaining self-tolerance in developing NK cells
ABclonal Technology PE Rabbit anti-Mouse CD47 mAb
Predicted to enable protein binding activity involved in heterotypic cell-cell adhesion and thrombospondin receptor activity Involved in regulation of nitric oxide biosynthetic process Acts upstream of or within several processes including monocyte aggregation opsonization and positive regulation of phagocytosis Located in extracellular exosome Is integral component of plasma membrane Is expressed in several structures including alimentary system central nervous system genitourinary system hemolymphoid system gland and liver and biliary system Orthologous to human CD47 (CD47 molecule)
ABclonal Technology PE Rabbit anti-Mouse CD87 mAb
Predicted to enable enzyme binding activity protein domain specific binding activity and signaling receptor binding activity Predicted to be involved in several processes including negative regulation of apoptotic signaling pathway positive regulation of epidermal growth factor receptor signaling pathway and positive regulation of release of cytochrome c from mitochondria Is integral component of plasma membrane Is expressed in several structures including decidua early conceptus and spleen Human ortholog(s) of this gene implicated in rheumatoid arthritis Orthologous to human PLAUR (plasminogen activator urokinase receptor)
ABclonal Technology PE Rabbit anti-Mouse CD204 mAb
Enables amyloid-beta binding activity cargo receptor activity and low-density lipoprotein particle binding activity Involved in several processes including endocytosis positive regulation of cholesterol storage and positive regulation of macrophage derived foam cell differentiation Acts upstream of or within establishment of localization in cell and lipoprotein transport Located in plasma membrane Is expressed in several structures including alimentary system early conceptus limb neural tube and reproductive system Human ortholog(s) of this gene implicated in Barrett s esophagus arteriosclerosis and prostate cancer Orthologous to human MSR1 (macrophage scavenger receptor 1)
ABclonal Technology Biotin Rabbit anti-Mouse CD11b
Enables complement component C3b binding activity heparan sulfate proteoglycan binding activity and heparin binding activity Contributes to cargo receptor activity Involved in several processes including central nervous system development endocytosis and positive regulation of neuron death Acts upstream of or within several processes including activated T cell proliferation leukocyte migration and microglia development Located in external side of plasma membrane and nucleus Is integral component of membrane Part of integrin alphaM-beta2 complex Is expressed in several structures including central nervous system heart lymphatic vessel thymus and yolk sac Human ortholog(s) of this gene implicated in lupus nephritis Orthologous to human ITGAM (integrin subunit alpha M)
ABclonal Technology APC Rabbit anti-Mouse CD22 mAb
Enables CD4 receptor binding activity protein phosphatase binding activity and sialic acid binding activity Involved in several processes including negative regulation of calcium-mediated signaling negative regulation of immunoglobulin production and regulation of B cell proliferation Located in external side of plasma membrane and neuronal cell body membrane Is integral component of plasma membrane Is expressed in several structures including alimentary system brain hemolymphoid system gland liver and biliary system and reproductive system Orthologous to human CD22 (CD22 molecule)
ABclonal Technology PE Rabbit anti-Mouse CD40 mAb
Predicted to enable antigen binding activity protein domain specific binding activity and ubiquitin protein ligase binding activity Involved in B cell mediated immunity CD40 signaling pathway and cellular calcium ion homeostasis Acts upstream of or within several processes including defense response to other organism positive regulation of B cell activation and positive regulation of interleukin-12 production Located in external side of plasma membrane and intracellular membrane-bounded organelle Part of CD40 receptor complex Is expressed in several structures including alimentary system brain hemolymphoid system gland liver and biliary system and reproductive system Human ortholog(s) of this gene implicated in several diseases including Kawasaki disease autoimmune disease (multiple) end stage renal disease hyperimmunoglobulin syndrome (multiple) and non-Hodgkin lymphoma (multiple) Orthologous to human CD40 (CD40 molecule)
ABclonal Technology APC Rabbit anti-Mouse CD4 mAb
Predicted to enable several functions including interleukin-16 binding activity interleukin-16 receptor activity and protein homodimerization activity Involved in helper T cell enhancement of adaptive immune response Acts upstream of or within several processes including defense response to Gram-negative bacterium positive regulation of calcium-mediated signaling and positive regulation of peptidyl-tyrosine phosphorylation Located in endoplasmic reticulum external side of plasma membrane and membrane raft Is expressed in several structures including alimentary system brain genitourinary system hemolymphoid system and liver and biliary system Used to study type 1 diabetes mellitus Human ortholog(s) of this gene implicated in immunodeficiency 79 Orthologous to human CD4 (CD4 molecule)
ABclonal Technology PE Rabbit anti-Mouse/Rat CD27
Predicted to enable cysteine-type endopeptidase inhibitor activity involved in apoptotic process Involved in negative regulation of apoptotic process and positive regulation of JNK cascade Acts upstream of or within negative regulation of T cell apoptotic process Located in external side of plasma membrane Is expressed in several structures including femur hemolymphoid system intestine pituitary gland and reproductive system Human ortholog(s) of this gene implicated in lymphoproliferative syndrome 2 Orthologous to human CD27 (CD27 molecule)
ABclonal Technology PE Rabbit anti-Mouse CD62L mAb
Enables cell adhesion molecule binding activity Acts upstream of or within response to ATP Located in external side of plasma membrane Is expressed in brain brainstem submandibular gland epithelium and testis Used to study type 1 diabetes mellitus Human ortholog(s) of this gene implicated in Crohn s disease IgA glomerulonephritis and ulcerative colitis Orthologous to human SELL (selectin L)
Jackson Immuno Research Labs Biotin-SP-AffiniPure Rabbit Anti-Mouse IgG (H+L) (min X Hu Sr Prot)
Biotin-SP-AffiniPure Rabbit Anti-Mouse IgG (H+L) (min X Hu Sr Prot)