Rabbit Secondary Antibodies
Cayman Chemical AMACRNTerm RabbIt Monclo 100uL
A heterocyclic building block has been used in the synthesis of prolyl-tRNA synthase inhibitors
ABclonal Technology ARFRP1 / ARP Rabbit mAb
The protein encoded by this gene is a membrane-associated GTP-ase which localizes to the plasma membrane and is related to the ADP-ribosylation factor (ARF) and ARF-like (ARL) proteins This gene plays a role in membrane trafficking between the trans-Golgi network and endosomes Alternatively spliced transcript variants encoding different isoforms have been identified
ABclonal Technology OXGR1 / GPR99 Rabbit mAb
This gene encodes a G protein-coupled receptor (GPCR) that belongs to the oxoglutarate receptor family within the GPCR superfamily The encoded protein is activated by the citric acid intermediate oxoglutarate as well as several cysteinyl leukotrienes including leukotrienes E4 C4 and D4 which are implicated in many inflammatory disorders In mice a knock-out of this gene leads to middle ear inflammation changes in the mucosal epithelium and an increase in fluid behind the eardrum and is associated with hearing loss Alternative splicing results in multiple transcript variants
ABclonal Technology ALDH7A1 Rabbit mAb
The protein encoded by this gene is a member of subfamily 7 in the aldehyde dehydrogenase gene family These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation This particular member has homology to a previously described protein from the green garden pea the 26g pea turgor protein It is also involved in lysine catabolism that is known to occur in the mitochondrial matrix Recent reports show that this protein is found both in the cytosol and the mitochondria and the two forms likely arise from the use of alternative translation initiation sites An additional variant encoding a different isoform has also been found for this gene Mutations in this gene are associated with pyridoxine-dependent epilepsy Several related pseudogenes have also been identified
United States Biological Corporation UNITED STATES BIOLOGICAL CORPORATION
NC3924900 RABBIT ANTI-CALCYON 200UL
ABclonal Technology SFT Rabbit mAb
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation Ubiquitination involves at least three classes of enzymes ubiquitin-activating enzymes or E1s ubiquitin-conjugating enzymes or E2s and ubiquitin-protein ligases or E3s This gene encodes a member of the E2 ubiquitin-conjugating enzyme family This enzyme is closely related to a stimulator of iron transport (SFT) and is up-regulated in hereditary hemochromatosis It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases Two transcript variants encoding different isoforms have been found for this gene
ABclonal Technology KPNA6 Rabbit mAb
Nucleocytoplasmic transport a signal- and energy-dependent process takes place through nuclear pore complexes embedded in the nuclear envelope The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor a heterodimer of importin alpha and beta subunits also known as karyopherins Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex In the presence of nucleoside triphosphates and the small GTP binding protein Ran the complex moves into the nuclear pore complex and the importin subunits dissociate Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore The protein encoded by this gene is a member of the importin alpha family
Abcam Rabbit Anti Cow Igg Hl Fitc AB102148-1MG
Rabbit Anti Cow Igg Hl Fitc AB102148-1MG
The product is subject to the following: Abcam Restricted Use Statement
ABclonal Technology GIRK2KCNJ6 Rabbit mAb
This gene encodes a member of the G protein-coupled inwardly-rectifying potassium channel family of inward rectifier potassium channels This type of potassium channel allows a greater flow of potassium into the cell than out of it These proteins modulate many physiological processes including heart rate in cardiac cells and circuit activity in neuronal cells through G-protein coupled receptor stimulation Mutations in this gene are associated with Keppen-Lubinsky Syndrome a rare condition characterized by severe developmental delay facial dysmorphism and intellectual disability
ABclonal Technology HSP40 Rabbit mAb
This gene encodes a member of the DnaJ or Hsp40 (heat shock protein 40 kD) family of proteins DNAJ family members are characterized by a highly conserved amino acid stretch called the J-domain and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events such as protein folding and oligomeric protein complex assembly The encoded protein is a molecular chaperone that stimulates the ATPase activity of Hsp70 heat-shock proteins in order to promote protein folding and prevent misfolded protein aggregation Alternative splicing results in multiple transcript variants
ABclonal Technology RPGR Rabbit mAb
This gene encodes a protein with a series of six RCC1-like domains (RLDs) characteristic of the highly conserved guanine nucleotide exchange factors The encoded protein is found in the Golgi body and interacts with RPGRIP1 This protein localizes to the outer segment of rod photoreceptors and is essential for their viability Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP) Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported but the full-length natures of only some have been determined