Rabbit Secondary Antibodies
ABclonal Technology 647 Rabbit anti-/Rat CD54
This gene encodes an integral membrane protein that binds leukocyte adhesion protein LFA-1 It participates in the innate immune response
Abcam Rabbit Fab'2 Anti-Rat IgG H&L Alexa Fluor 488
Rabbit Fab'2 Anti-Rat IgG H&L Alexa Fluor 488
The product is subject to the following: Abcam Restricted Use Statement
ABclonal Technology ABflo 488 Rabbit anti- CD40
Predicted to enable antigen binding activity protein domain specific binding activity and ubiquitin protein ligase binding activity Involved in B cell mediated immunity CD40 signaling pathway and cellular calcium ion homeostasis Acts upstream of or within several processes including defense response to other organism positive regulation of B cell activation and positive regulation of interleukin-12 production Located in external side of plasma membrane and intracellular membrane-bounded organelle Part of CD40 receptor complex Is expressed in several structures including alimentary system brain hemolymphoid system gland liver and biliary system and reproductive system Human ortholog(s) of this gene implicated in several diseases including Kawasaki disease autoimmune disease (multiple) end stage renal disease hyperimmunoglobulin syndrome (multiple) and non-Hodgkin lymphoma (multiple) Orthologous to human CD40 (CD40 molecule)
Jackson Immuno Research Labs Cy3-AffiniPure Rabbit Anti-Mouse IgG F(ab')2 Fragment Specific
Cy3-AffiniPure Rabbit Anti-Mouse IgG F(ab')2 Fragment Specific
ABclonal Technology PerCP Rabbit anti-Mouse CD8a
Enables identical protein binding activity Acts upstream of or within several processes including cytotoxic T cell differentiation defense response to virus and positive regulation of calcium-mediated signaling Located in external side of plasma membrane Is expressed in several structures including endocrine gland exocrine gland genitourinary system gut and hemolymphoid system gland Orthologous to human CD8A (CD8a molecule)
Jackson Immuno Research Labs Rhodamine Red-X-AffiniPure Rabbit Anti-Mouse IgG Fcγ Fragment Specific (min X Hu Sr Prot)
Rhodamine Red-X-AffiniPure Rabbit Anti-Mouse IgG Fcγ Fragment Specific (min X Hu Sr Prot)
ABclonal Technology PE Rabbit anti-Mouse CD32 mAb
CD32 (Fcgr2) is a 40 kD transmembrane glycoprotein member of the immunoglobulin superfamily The extracellular region of CD32 consists of two Ig C-type domains that binds the Fc region from monomeric IgG with low affinity but binds immune complexes efficiently CD32 can mediate phagocytosis of immune complexes and modulate cell activation CD32 is expressed by Macrophages neutrophils mast cells and B cells
ABclonal Technology PE Rabbit anti-Mouse CD103 mAb
Predicted to enable metal ion binding activity Predicted to act upstream of or within cell adhesion and integrin-mediated signaling pathway Located in external side of plasma membrane Is expressed in several structures including alimentary system genitourinary system lymph node nasal septum and nucleus pulposus Orthologous to human ITGAE (integrin subunit alpha E)
ABclonal Technology PE Rabbit anti-Mouse Ly-49D
Predicted to enable carbohydrate binding activity Predicted to act upstream of or within cell adhesion Located in external side of plasma membrane
Jackson Immuno Research Labs Alexa Fluor 488-AffiniPure F(ab')2 Fragment Rabbit Anti-Mouse IgG Fcγ Fragment Specific (min X Hu Sr Prot)
Alexa Fluor 488-AffiniPure F(ab')2 Fragment Rabbit Anti-Mouse IgG Fcγ Fragment Specific (min X Hu Sr Prot)
Biotium CD28(C28/77), CF594 conjugate, 0.1mg/mL
Recognizes a glycoprotein of 44-88 kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Biotium CD53(161-2), CF594 conjugate, 0.1mg/mL
Recognizes a protein of 33-55 kDa, identified as CD53 (Workshop VI; Code N-L033). It is expressed on monocytes and macrophages, dendritic cells, osteoblasts and osteoclasts, and on T and B cells from every stage of differentiation but is absent from platelets, red blood cells. CD53 appears to be the marker with widest reactivity as well as the marker with the strictest specificity to hematopoietic cells. CD53 is a type III membrane with both termini in the cytoplasm and two loops in the extracellular environment. This molecule, in common with other members of tetraspan family, is involved in cellular activation as part of a signal transduction complex involving other membrane glycoproteins. CD53 crosslinking induces calcium flux on human monocyte and B cells. Cross-linking of CD53 promotes activation of resting human B-lymphocytes. This MAb recognizes CD53 transfected cells and partially inhibits T-cell proliferation induced by CD3 antibody (clone: UCHT1).Primary antibodies a
Biotium CD33(C33/69), CF594 conjugate, 0.1mg/mL
Recognizes a 67 kDa glycoprotein, which is identified as CD33. It is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies; these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia. CD33 is expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells. It is absent on platelets, lymphocytes, erythrocytes and hematopoietic stem cells.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluor
Biotium CD66 (CEA)(C66/195), CF594 conjugate, 0.1mg/mL
This antibody recognizes proteins of 80-200 kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb reacts with nonspecific cross-reacting antigen (NCA) and shows a cross-reaction with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA ) from pleural mesotheliomas (rarely or weakly CEA ). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.Primary antibodies are available purified, or with a selection of fluorescent CF Dy