DNA Synthesis Reagents and Columns
Abcam 20(S)-Hydro x ycholesterol, Smoothened activator, 1MG
MW 402.65 g/mol. Allosteric activator of the Hedgehog (Hh) signaling pathway Smoothened (Smo) oncoprotein. Binds at a site distinct from the canonical cyclopamine binding site. Activates Hh signaling (EC₅₀ = ~ 3 μM for induction of Hh reporter gene transcription in NIH 3T3 cells). Also exhibits osteogenic activity and activates the liver X receptor (LXR).
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical 5-methoxy DMT N-oxIde 5mg
An alkaloid reduces LPS-induced production of TNF-a in RAW 264 7 cells at 50 UM
Cayman Chemical Humn ActIvatr ProteIn1 Rep
An inhibitor of SOC channels (IC50 1.7 UM in HL-60 leukemia cells) and Cav1 channels (IC50 2.1 UM in GH4C1 rat pituitary cells) reduces thapsigargin-induced calcium entry in isolated rat PMNs after administration of a 1.2 mg/kg dose decreases shock-induced increases in ITGAM/CD11b levels in isolated rat PMNs in a model of traumatic hemorrhagic shock at 1.2 mg/kg
TARGETMOL CHEMICALS INC AMPK activator 12 5MG
Also available in 1 mL, 1 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. AMPK activator 12 is an AMPK activator and GDF15 inducer that elevates the expression level of GDF15 protein in human hepatocytes, which can be used for cancer research. Purity 99.27%
