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Chemical reagents, kits, columns, and other products used for DNA synthesis, and to subsequently run purification columns; includes genetic assembly systems.
The Enceed T cell Activation human (GMP) is used for in vitro activation and expansion of enriched T cells or peripheral blood mononuclear cells (PBMCs) Due to the nanoscale structure of Enceed T cell Activation human (GMP) the excess reagent can be removed by centrifugation or conventional supernatant replacement
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An activator of EIF2AK1/HRI; activates HRI and induces eIF2α phosphorylation in a surrogate cell-based reporter assay; selectively inhibits the proliferation of CRL-2813 cells over NIH3T3 fibroblasts (IC50s = 0.46 and 3.4 µM, respectively); selectively inhibits the proliferation of CRL-2813 cells transiently transfected with non-targeted siRNA over CRL-2813 cells transiently transfected with HRI-targeted siRNA (IC50s = 0.66 and 5 µM, respectively); increases mRNA expression and protein levels of the eIF2α target CHOP in CRL-2813 cells at 5 µM
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MW 252.22 Da, Purity >98%. Thymidine analog. Alternative to BrdU (5-Bromo-2'-deoxyuridine) (ab142567) for measuring de novo DNA synthesis during S-phase. Cytotoxic anti-metabolite. Used for probing short-term DNA synthesis in tissue culture and living organisms where prolonged cell survival is not required.