DNA Synthesis Reagents and Columns
Cayman Chemical eIF2a ActIvatr 2 5mg
An activator of EIF2AK1/HRI; activates HRI and induces eIF2α phosphorylation in a surrogate cell-based reporter assay; selectively inhibits the proliferation of CRL-2813 cells over NIH3T3 fibroblasts (IC50s = 0.46 and 3.4 µM, respectively); selectively inhibits the proliferation of CRL-2813 cells transiently transfected with non-targeted siRNA over CRL-2813 cells transiently transfected with HRI-targeted siRNA (IC50s = 0.66 and 5 µM, respectively); increases mRNA expression and protein levels of the eIF2α target CHOP in CRL-2813 cells at 5 µM
Sigma Aldrich Fine Chemicals Biosciences Capping Reagent A THF/Pyridine/Acetic Anhydride Biosynthesis Novabiochem(R) |
Capping Reagent A THF/Pyridine/Acetic Anhydride Biosynthesis Novabiochem(R) |
Berry & Associates Inc Universal Support Column, 1000 Å pore size, DMT off, N-iPr linker, MerMade column format, 1 μmol synthesis scale
The LGC Biosearch Technologies MM1-3500-1 is a Universal Support Column optimized for 1 μmol oligonucleotide synthesis. Made with controlled-pore glass, this product features a 1000 Å pore size and utilizes a DMT-off design, ensuring a faster cleavage rate and simplifying the synthesis process. This universal support allows for the flexibility of determining the 3'-end nucleobase during the initial phosphoramidite addition, promoting easier supply chain management for oligonucleotide synthesis applications.
- Product type: Universal support column
- Solid support material: Controlled-pore glass (CPG)
- Pore size: 1000 Å
- Functional loading: Up to 55 μmol/g
- DMT status: DMT off (unprotected)
- Linker type: N-iPr (isopropyl)
- Linker cleavage rate: 5 times faster than N-Ph version
- Synthesis scale: 1 μmol
- Column type: MerMade
- Application: Oligonucleotide synthesis