Margatoxin is an alpha-KTx scorpion toxin, a 39 amino acid peptide isolated from the venom of the Centruroides margaritatus scorpion. It functions as a high-affinity inhibitor of Kv1.3, Kv1.2, and Kv1.1 potassium channels, making it a valuable tool in ion channel research.
- High-affinity inhibitor of Kv1.3, Kv1.2, and Kv1.1 potassium channels
- 39 amino acid peptide
- Derived from *Centruroides margaritatus* scorpion venom
- Used in ion channel research
- Decreases thioglycollate-induced leukocyte transmigration in vivo