Apoptosis Reagents and Kits
AdipoGen b-AP15
Chemical. CAS 1009817-63-3. Formula C22H17N3O6. MW 419.4. b-AP15 is a specific deubiquitinase DUB inhibitor. It inhibits ubiquitin-specific-processing protease 14 USP14 and ubiquitin c-terminal hydrolase isozyme L5 UCHL5 UCH37, two 19S regulatory particle proteasome-associated DUBs. It exhibits minimal inhibition of UCHL-1, UCHL-3, USP2, USP7, USP and BAP1. Has been described to inhibit also the 20S proteasome with an IC50 comparable to that required for inhibiting the 19S regulatory particles. b-AP15 has anticancer properties and blocks tumor progression in vivo in mice and prevents organ infiltration in mouse models of myeloid leukemia. b-AP15 also renders tumor cells sensitive to TNF-mediated apoptosis by natural killer and T cells. It induces apoptosis, ER stress and autophagy in several cancer cells. b-AP15 has anti-inflammatory properties inhibiting ERK1/2 and JNK phosphorylation, increasing IkappaBalpha levels and inhibiting NF-kappaB p65.
Abcam Human IRAK4 Matched Antibody Pair Kit, 5 x 96 Tests
Human IRAK4 Matched Antibody Pair Kit is a kit for ELISA development for the measurement of Human IRAK4 by sandwich ELISA method.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human GIT1 knockout HeLa cell lysate.
Human GIT1 knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Biolegend PerCP/Cyanine5.5 Annexin V
PerCP/Cyanine5.5 Annexin V Reactivity: All mammalian species; Apps: FC; Size: 100 tests
ABclonal Technology FLCN Rabbit pAb
This gene is located within the Smith-Magenis syndrome region on chromosome 17. Mutations in this gene are associated with Birt-Hogg-Dube syndrome, which is characterized by fibrofolliculomas, renal tumors, lung cysts, and pneumothorax. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Abcam Human CEACAM1 knockout A549 cell lysate.
Human CEACAM1 knockout A549 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human A-Raf knockout HEK-293T cell lysate.
Human A-Raf knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human TOP2B (Topoisomerase II beta) knockout HEK-293T cell lysate.
Human TOP2B (Topoisomerase II beta) knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human NT5E knockout A-431 cell lysate.
Human NT5E knockout A-431 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC Annexin A1/ANXA1 Mo 1mg
Annexin A1 (ANXA1) Protein, Mouse (His) is a full-length recombinant mouse annexin A1 expressed in Escherichia coli with an N-terminal 6xHis tag, supplied as a lyophilized powder. The protein is >95% pure, has an approximate molecular weight of 40 kDa, and low endotoxin (<1 EU/μg); it is formulated with trehalose for stability and intended for in vitro studies of inflammation, immune signaling, phagocytosis, and chemotaxis.
- Full-length recombinant protein with N-terminal His tag.
- Expressed in Escherichia coli for scalable production.
- Purity greater than 95% by reducing SDS-PAGE.
- Approximately 40 kDa molecular weight.
- Low endotoxin level (<1 EU/μg) suitable for cell-based assays.
- Lyophilized formulation with trehalose for enhanced stability.
- Demonstrated biological activity in suppressing TNF-alpha secretion in RAW264.7 cells.
- Multiple size options available to fit experimental needs.
Abcam Human CPT1A knockout HEK-293T cell lysate.
Human CPT1A knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
ABclonal Technology Annexin A2 Rabbit pAb
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. Annexin A2 expression has been found to correlate with resistance to treatment against various cancer forms.
Abcam Human ITGA6 (Integrin alpha 6) knockout HeLa cell lysate.
Human ITGA6 (Integrin alpha 6) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam JC-10 Mitochondrial Membrane Potential Assay Kit (Microplate)
JC-10 Mitochondrial Membrane Potential Assay Kit (Microplate)
The product is subject to the following: Abcam Restricted Use Statement
Abcam Apoptosis Western Blot Cocktail (pro/p17-caspase-3, cleaved PARP1, muscle actin)
Apoptosis Western Blot Cocktail (pro/p17-caspase-3, cleaved PARP1, muscle actin)
The product is subject to the following: Abcam Restricted Use Statement