Nitric oxide (NO) independent, superoxide-sensitive stimulator of soluble guanylyl cyclase (sGC), EC50=18.6μM. Induces concentration-dependent increase in cGMP levels in cultured cells and in rabbit aortic rings. Inhibits platelet adhesion to collagen. Non-specific phosphodiesterase inhibitor. YC-1 inhibits HIF-α activity in tumors resulting in blocked angiogenesis and an inhibition of tumor growth. Inhibits Na+ channel.Binds to [3H]BW202W92. Purity: ≥98% (HPLC). Appearance: White to pale yellow powder. Solubility: Soluble in DMSO, methanol or dichloromethane. Long Term Storage: +4°C.