Signal Transduction Reagents and Kits
Enzo Life Sciences SB-202190 (1mg). CAS: 152121-30-7
Cell permeable, potent and selective p38 MAP kinase inhibitor (IC50=30 nM). Inhibits p38α and ß, but not γ and δ isoforms. Does not inhibit ERK2 or other members of the MAP kinase family or their upstream activators. A useful tool for dissecting the role of p38 in signaling pathways. Induces apoptosis. Alternative name: FHPI, 4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)-1H-imidazole. Purity: ≥98% (TLC). Solubility: Soluble in methanol, DMSO or acetone; slightly soluble in ethyl acetate. Long Term Storage: -20°C.
Enzo Life Sciences E-64-D, (1mg), CAS Number: 88321-09-9
Calpain and cathepsin inhibitor. Cell-permeable, ethyl ester of E-64-c. The ester is hydrolyzed by intracellular esterases to produce E-64-c. Inhibits calpain and cathepsins B, H, and L. Inhibits degradation of autophagic cargo inside autophagolysosomes. Alternative Name: 2S,3S-trans-(Ethoxycarbonyloxirane-2-carbonyl)-L-leucine-(3-methylbutyl) amide. Aloxistatin. Formula: C17H30N2O5. MW: 342.4. CAS Number: 88321-09-9. Purity: ≥98% (HPLC). Appearance: White solid. Solubility: Soluble in 100% ethanol (>10mg/ml) or DMSO (20mg/ml). Use/Stability: Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 2 months. Long Term Storage: -20°C
Hach Company General Purpose Contacting Conductivity Sensor, Ryton Body, K=10.0 Cell Constant
Nominal Cell Constant (K) = 10.0, 3/4 inch male NPT threaded Ryton body, 6m (20ft) Analog Cable, Graphite Electrode
Enzo Life Sciences 1-Oleoyl-2-acetyl-sn-glycerol (10mg). CAS: 86390-77-4
In vitro potent activator of protein kinase C (PKC). Stimulator of secretion and aggregation in blood platelets. Stimulates formation of actin nucleation sites. Stimulation of pp60c-src phosphorylation in EBV transformed B-cells, 470μM. Alternative name: OAG. Purity: ≥98% (TLC). Solubility: Soluble in DMSO or ethanol. Long Term Storage: -20°C.
Carnabio Usa Inc MRCKA(CDC42BPA)/10UG/TRUNCATED
MRCK(CDC42BPA), Truncated protein, Wild type, Amino Acid 1-574, NP_003598.2, Expressed in Insect (sf21); 10microg
Aat Bioquest Calbryte™ 520 AM | 2x50ug
The intracellular calcium flux assay is a widely used method in monitoring signal transduction pathways and high throughput screening of G protein"coupled receptors (GPCRs) and calcium channel targets. Followed by Fluo-3 being introduced in 1989, Fluo-4, Fluo-8 and Cal-520 were later developed with improved signal/background ratio, and became the widely used Ca2+ indicators for confocal microscopy, flow cytometry and high throughput screening applications. However, there are still a few severe problems with Fluo-4. For example, as for Fluo-3, in all most all the intracellular calcium assays with Fluo-4 AM, probenecid is required to prevent the cell-loaded Fluo-4 from leaking out of cells. The use of probenecid with Fluo-4-based calcium assays compromises the assay results since probenecid is well-documented to have a variety of complicated cellular effects. Calbryte™ 520, AM is a novel fluorescent and cell-permeable indicator for the measurement of intracellular calcium.
Enzo Life Sciences PROTEOSTAT Thioredoxin-1 assay kit (2x96wells)
Applications: Fluorescent detection. Contents: PROTEOSTAT PDI detection reagent: 20 μL. Thioredoxin-1 (human) (recombinant): 2 vials x 80 μL. Insulin: 2 vials x 1.8 μmol. Aurothiomalate (inhibitor): 2 vials x 25 nmol. PBE buffer: 25 mL. Stop reagent: 1 mL. DTT: 2 vials x 1.3 mL. Deionized water: 5 mL
Sigma Aldrich Fine Chemicals Biosciences (+)-BICUCULLINE-100MG
(+)-Bicuculline, 100MG, CAS# 485-49-4, MFCD00005006, MOLWT: 367.35
AdipoGen SB202190 (1 mg)
SB202190 (1 mg), Adipogen Life Sciences. Chemical. CAS: 152121-30-7. Formula: C20H14FN3O. MW: 331.3. Potent and cell permeable p38 MAP kinase inhibitor. Apoptosis inducer. Inhibits p38alpha and beta, but not gamma and delta isoforms. Does not inhibit ERK2 or other members of the MAP kinase family or their upstream activators. JNK activator. Autophagic vacuole inducer
Sigma Aldrich Fine Chemicals Biosciences PGO Enzyme Preparation 1 G capsules | 10CAP
PGO Enzyme Preparation 1 G capsules | 10CAP