Signal Transduction Reagents and Kits
Echelon Biosciences Research Labs TNF converting Enzyme Substrate - 5 mg, CAS#: 192723-42-5
TNF converting Enzyme Substrate - 5mg , Mca-Pro-Leu-Ala-Gln-Ala-Val-Dpa-Arg-Ser-Ser-Ser-Arg-NH2 Category/Application: Enzyme Substrates This item is non returnable
Echelon Biosciences Research Labs GERANYLGERANIOL 10 mg
(E,E,E)-Geranylgeraniol is an intermediate in the biosynthetic pathway of vitamins E & K and is linked to proteins via post-translational modification. This item is non returnable
Echelon Biosciences Research Labs PI(5)P DIC8 AMMONIUM SALT 100 ug
Phosphatidylinositol 5-phosphate diC8 (PI(5)P diC8) is a synthetic, purified dioctanoyl PI(5)P.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 5-phosphate (PI(5)P) is a rare lipid found in the nucleus that can bind the PHD finger of the nuclear adapter protein ING2. PI(5)P is phosphorylated to PI(4,5)P2 by Type II PIP kinases. This item is non returnable
Neogen Diagnostics K-Blue Luminescent Substrate, 200 ML, HRP, Microwell, Chemiluminescent
K-Blue Luminescent is a stabilized luminescent substrate for use with horseradish peroxidase immunoassays. It contains both luminol and hydrogen peroxide (H2O2) in a two-bottle format with long-term stability, high sensitivity, and excellent signal to noise. Maximal light emission occurs at 430 nm in the presence of peroxidase labeled conjugate. K-Blue Luminescent is compliant with Annex XVII for REACH and contains no hazardous substances at or above published reporting levels. Stable for a minimum of 18-months when stored at 2-8C.
Abcam ZIP, protein kinase Czeta (PKC-zeta) inhibitor
Novel, cell-permeable protein kinase Cζ (PKCζ) inhibitor
The product is subject to the following: Abcam Restricted Use Statement
Echelon Biosciences Research Labs PI(5)P DIC8 AMMONIUM SALT 1 mg
Phosphatidylinositol 5-phosphate diC8 (PI(5)P diC8) is a synthetic, purified dioctanoyl PI(5)P.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 5-phosphate (PI(5)P) is a rare lipid found in the nucleus that can bind the PHD finger of the nuclear adapter protein ING2. PI(5)P is phosphorylated to PI(4,5)P2 by Type II PIP kinases. This item is non returnable
Echelon Biosciences Research Labs BODIPY FL-PI(3,5)P2 100 ug
BODIPY FL PI(3,5)P2 (BODIPY FL Phosphatidylinositol 3,5-bisphosphate) is a water soluble analog of PI(3,5)P2 labeled with the green fluorophore, Bodipy-FL at the sn-1 position.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3,5-bisphosphate is in very low abundance and is required for retrograde membrane trafficking from lysosomal and late endosomal compartments to the Golgi and is involved in autophagy. PI(3,5)P2 levels are controlled by the 5-kinase PIKfyve and the 5-phosphatase Fig4/Sac3 and disregulation is linked to several human neuropathies (eg Chacot-Marie-Tooth disease). This item is non returnable
Echelon Biosciences Research Labs GLO-PI(3,4,5)P3BODIPYTMR100ug
BODIPY TMR PI(3,4,5)P3 (BODIPY TMR Phosphatidylinositol 3,4,5-trisphosphate) is a water soluble analog of PI(3,4,5)P3 (PIP3) labeled with the orange fluorophore, Bodipy-TMR, at the sn-1 position.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3,4,5-trisphosphate (PIP3), formed from PI(4,5)P2 though phosphorylation by PI 3-kinase, activates numerous signaling pathways resulting in cell proliferation, growth, survival, glucose transport and protein synthesis. High PIP3 levels from disregulation of PI3-K have been demonstrated in cancer and inflammatory diseases. PIP3 is hydrolyzed by the phosphatases PTEN to PI(4,5)P2 and SHIP to PI(3,4)P2. This item is non returnable
Hach Company General Purpose Contacting Conductivity Sensor, Ryton Body, K=10.0 Cell Constant
Nominal Cell Constant (K) = 10.0, 3/4 inch male NPT threaded Ryton body, 6m (20ft) Analog Cable, Graphite Electrode
Abcam Forskolin, Adenylyl cyclase activator, 5MG
MW 410.5 Da. Cell-permeable activator of adenylyl cyclase. Interacts directly with the catalytic subunit of the enzyme to increase intracellular cAMP levels. Positive inotropic, platelet antiaggregatory and antihypertensive actions in vivo. 3D Growth matrix component used in liver organoid generation.
The product is subject to the following: Abcam Restricted Use Statement
Sigma Aldrich Fine Chemicals Biosciences (+)-BICUCULLINE-100MG
(+)-Bicuculline, 100MG, CAS# 485-49-4, MFCD00005006, MOLWT: 367.35
Enzo Life Sciences SB-202190 (1mg). CAS: 152121-30-7
Cell permeable, potent and selective p38 MAP kinase inhibitor (IC50=30 nM). Inhibits p38α and ß, but not γ and δ isoforms. Does not inhibit ERK2 or other members of the MAP kinase family or their upstream activators. A useful tool for dissecting the role of p38 in signaling pathways. Induces apoptosis. Alternative name: FHPI, 4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)-1H-imidazole. Purity: ≥98% (TLC). Solubility: Soluble in methanol, DMSO or acetone; slightly soluble in ethyl acetate. Long Term Storage: -20°C.