Modifying Enzymes
Sigma Aldrich Fine Chemicals Biosciences beta-Galactosidase from bovine liver Grade III, lyophilized powder, >=0.15 units/mg protein | 9031-11-2 | MFCD00130623 | 10UN
beta-Galactosidase from bovine liver Grade III, lyophilized powder, >=0.15 units/mg protein | 9031-11-2 | MFCD00130623 | 10UN
Medchemexpress LLC HY-110115 5mg Medchemexpress, TC-Mps1-12 CAS:1206170-62-8 Purity:>98%
Medchemexpress, HY-110115 5mg TC-Mps1-12 CAS:1206170-62-8 TC-Mps1-12 is a potent and selective monopolar spindle 1 (Mps1) inhibitor, with an IC50 of 6.4 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
ABclonal Technology Endonuclease VIII
Endonuclease VIII originates from E.coli and possesses both N-glycosylase and AP-endonuclease activity. The N-glycosylase activity releases damaged pyrimidines from double-stranded DNA, generating an apurinic (AP site). The AP-endonuclease the phosphodiester bond at the AP site, forming 3’-P and 5’-P ends. Damaged bases recognized and removed by Endonuclease VIII include: urea, 5, 6-dihydroxythymine, thymine glycol, 5-hydroxy-5-methylhyd antoin, uracil glycol, 6-hydroxy-5, 6-dihydrothymine and methylhydroxy- methyluracil.
Sigma Aldrich Fine Chemicals Biosciences n Heptanoyl coenzyme A lit5MG
n Heptanoyl coenzyme A lit5MG
Cayman Chemical Lysosomal ACD LIpase ActIvIt
Cayman's LAL Activity MaxSpec Assay Kit includes the necessary reagents to quantify lysosomal acid lipase (LAL) activity in dried blood spots. The LAL Activity MaxSpec Assay Substrate (P-PMHC) has been designed to function as a highly selective substrate for LAL, which hydrolyzes the fatty acyl group of P-PMHC resulting in the formation of the LAL Activity MaxSpec Assay Product 4-propyl-8-methyl-7-hydroxycoumarin (PMHC). Using the LAL Activity MaxSpec Assay Kit, LAL activity may be quantified directly by fluorometry or by LC-MS in combination with the LAL Activity MaxSpec Assay Internal Standard.
Carnabio Usa Inc MARK2/10UG/FULL-LENGTH
MARK2, Full-length, Wild type, Amino Acid 1-745, NP_059672.2, Expressed in Insect (sf21); 10microg
Medchemexpress LLC HY-19801 5mg Medchemexpress, CVT-10216 CAS:1005334-57-5 Purity:>98%
Medchemexpress, HY-19801 5mg CVT-10216 CAS:1005334-57-5 CVT-10216 is a highly selective, reversible aldehyde dehydrogenase-2 (ALDH-2) inhibitor with an IC50 of 29 nM. CVT-10216 also has inhibitory effect of ALDH-1 with an IC50 of 1.3 μM. CVT-10216 can reduce excessive alcohol drinking in alcohol-preferring rats and exhibit anxiolytic effects. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Sigma Aldrich Fine Chemicals Biosciences Proteinase K from Tritirachium album Reagents designed and manufactured under current ISO 13485 certification. | 39450-01-6 | MFCD00132129 | 5ML
Proteinase K from Tritirachium album Reagents designed and manufactured under current ISO 13485 certification. | 39450-01-6 | MFCD00132129 | 5ML
Cayman Chemical Oleoyl-L-carnItIn 10mg
A long-chain acylcarnitine and GlyT2 inhibitor (IC50 = 340 nM); selective for GlyT2 over GlyT1 (IC50 = >10,000 nM); plasma levels are increased in patients with chronic kidney disease or end-stage renal disease receiving incident hemodialysis and these are associated with cardiovascular mortality
![Medchemexpress LLC N-cyclobutyl-6-[2-(3-fluorophenyl)ethynyl]-3-pyridinecarboxamide | 1310012-12-4 | 98.1% | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000234369.png-250.jpg)
Medchemexpress LLC N-cyclobutyl-6-[2-(3-fluorophenyl)ethynyl]-3-pyridinecarboxamide | 1310012-12-4 | 98.1% | 50 MG
VU0360172 is a potent and selective positive allosteric modulator of the metabotropic glutamate receptor 5 (mGlu5) used as a research reagent for cellular and in vivo pharmacology studies.
- Potent mGlu5 positive allosteric modulation (EC50 16 nM).
- Binding affinity to mGlu5 (Ki 195 nM).
- High purity suitable for research (98.1%).
- Molecular formula C18H15FN2O and molecular weight 294.32 g/mol.
- Solid, light yellow to brown research material supplied as 50 MG quantities.
Cayman Chemical N-Oleoyl ProlIn 1mg
An endogenous N-acyl amine that is decreased in lumbar spinal cord after capsaicin administration (1 UG/10 µl) and has surfactant properties (critical micelle concentration = 4.8 µM)
Cayman Chemical Monoacylglycerol Lipase FL P
Immunogen: Purified recombinant human MAGL • Host: Rabbit • Species Reactivity: (+) Human and rat; other species not tested • Applications: ICC, IHC, and WB
Apexbio Technology LLC EZ Cap CM-EGFP Probe mRNA (m1Ψ) 5x1mg (1mg/mL)
CM-EGFP mRNA encodes a fusion protein comprised of a cell membrane (CM) targeting signal sequence and enhanced green fluorescent protein (EGFP) By fusing EGFP with a membrane localization signal this probe enables real-time visualization of dynamic changes occurring at the cell membrane of living cells particularly beneficial for research involving cell membrane-related processes such as signal transduction membrane protein interactions and alterations in membrane structure EZ Cap CM-EGFP Probe mRNA (m1 ) is provided at 1 mg/mL It is specifically designed for cell membrane-specific expression of a green fluorescent protein label This mRNA is synthesized through co-transcriptional capping resulting in a Cap 1 structure The incorporation of m1 modifications poly(A) tail significantly enhances mRNA stability and lifetime both in vitro and in vivo
Carnabio Usa Inc QIK(SNF1LK2)/10UG/FULL-LENGTH
QIK(SNF1LK2), Full-length, Wild type, Amino Acid 1-926, NP_056006.1, Expressed in Insect (sf21); 10microg
New England Biolabs, Inc. Endonuclease VIII – 5000 units
Endonuclease VIII from E. coli acts as both an N-glycosylase and an AP-lyase. The N-glycosylase activity releases damaged pyrimidines from double-stranded DNA, generating an apurinic (AP site). The AP-lyase activity cleaves 3' and 5' to the AP site leaving a 5' phosphate and a 3' phosphate. Damaged bases recognized and removed by Endonuclease VIII include urea, 5, 6- dihydroxythymine, thymine glycol, 5-hydroxy-5- methylhydantoin, uracil glycol, 6-hydroxy-5, 6-dihydrothymine and methyltartronylurea. While Endonuclease VIII is similar to Endonuclease III, Endonuclease VIII has and lyase activity while Endonuclease III has only lyase activity.