Modifying Enzymes
Cayman Chemical Heptnoyl-Coenzyme AsodIum 1mg
A medium-chain acyl CoA; inhibitsbutyryl-CoA:acetate-CoA transferase isolated from P. elsdenii at 200 µM; levels are increased in primary fibroblasts derived from patients with MCAD deficiency in the presence of heptanoic acid; blocks berberine-induced decreases in infarct volume and improvements in motor function in a mouse model of MCAO-induced ischemic stroke at 0.4 mg/kg per day
Cayman Chemical Pentnoyl-Coenzyme AsodIum 5mg
A saturated acyl CoA and metabolite of 3-oxovalproyl-CoA; hepatic levels of pentanoyl-CoA and propionyl-CoA are increased in an Apc+/Min-FCCC mouse model of spontaneous colorectal cancer fed a low- or high-fat diet
Cayman Chemical Heptnoyl-Coenzyme AsodIum 5mg
A medium-chain acyl CoA; inhibitsbutyryl-CoA:acetate-CoA transferase isolated from P. elsdenii at 200 µM; levels are increased in primary fibroblasts derived from patients with MCAD deficiency in the presence of heptanoic acid; blocks berberine-induced decreases in infarct volume and improvements in motor function in a mouse model of MCAO-induced ischemic stroke at 0.4 mg/kg per day
Cayman Chemical E3 LIgase LIgnd 2 5g
An active metabolite of thalidomide and a PROTAC synthetic intermediate; decreases production of TNF-α induced by TPA in THP-1 cells at 30 µM; completely inhibits the proliferation HUVECs at 333 µM; inhibits VEGF- and FGF2-induced angiogenesis by 14% in a CAM assay in utero at 100 UG/embryo