DNA Vectors
Vector Biolabs Akt1 (dn) Adenovirus (Ad-CMV-Akt1 (dn))
An HA tag was fused in frame to the N termini of the coding sequence of mouse Akt1(T308A, S473A) mutant, which is also known as Akt1(AA). Akt1/PKB is activated in response to many extracellular signals and play key roles in regulating diverse cellular processes, including cell proliferation, differentiation, apoptosis, angiogenesis and glycogen synthesis etc. Akt1 is activated by the phosphorylation of the T loop of their kinase domain by PDK1 and by phosphorylation of a residue located C-terminal to the kinase domain in the hydrophobic motif. The Akt family of kinases includes Akt1, Akt2 and Akt3.
Vector Biolabs human STK16 shRNA Adenovirus (Ad-h-STK16-shRNA)
This is an pre-made gene silencing adenovirus that expresses a shRNA to knockdown human STK16 gene. The shRNA expression is driven by an U6 promoter.
The knockdown of this human gene was validated by qPCR in A549 cells.
Vector Biolabs human LMNA shRNA Adenovirus (Ad-h-LMNA-shRNA)
This is an pre-made gene silencing adenovirus that expresses a shRNA to knockdown human LMNA gene. The shRNA expression is driven by an U6 promoter.
The knockdown of this human gene was validated by western blot in SKMel-28 cells.
Vector Biolabs human P53 (TP53) shRNA Adenovirus (Ad-h-P53 (TP53)-shRNA)
This is an pre-made gene silencing adenovirus that expresses a shRNA to knockdown human P53 (TP53) gene. The shRNA expression is driven by an U6 promoter.
The knockdown of this human gene was validated by western blot in A549 cells.
Vector Biolabs pre-synthesized DNA vector
Protein phosphatase 1 regulatory (inhibitor) subunit 1A Adenovirus (Ad-PP1-R1)
Vector Biolabs Tet-on inducible beta-gal/LacZ Adenovirus (Ad-Tet-on-bgal)
beta-galactosidase is under the control of a tetracycline-regulated promoter.
Vector Biolabs AAV-GFP (AAV serotype 8) AAV (AAV8-GFP)
This AAV serotype 8 virus (with Capsid from AAV8 and ITR from AAV2) expresses eGFP. eGFP expression is under the control of CMV promoter.
Vector Biolabs Scramble shRNA (AAV serotype 1) AAV (AAV1-GFP-U6-shRNA)
This AAV expresses a scramble shRNA sequence under the control of U6 promoter, with the GFP co-expression under a CMV promoter. This AAV is a serotype 1 virus (with Capsid from AAV1 and ITR from AAV2)
BIOHIPPO AAV-CMV-mRFP1-EGFP-LC3B(R)-WPRE-hGH-polyA
Recombinant adeno associated virus expressing LC3B(R) fused to mRFP1 EGFP under the CMV promoter with WPRE and hGH polyA elements. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
