Nucleic Acid Synthesis
Medchemexpress LLC Trifluridine/tipiracil hydrochloride mixture | 733030-01-8 | 100.0% | 435.76 | 25 MG
Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a potent and orally active nucleoside antitumor agent. It is composed of a 1:0.5 mixture (on a molar basis) of alpha,alpha,alpha-tri-fluorothymidine (FTD) and thymidine phosphorylase inhibitor (TPI). The antitumor activity of TAS-102 primarily stems from its inhibition of thymidylate synthase (TS) and its incorporation into DNA.
- Prevents body weight loss in colorectal and gastric cancer mouse models.
- Reduces relative tumor volume in colorectal and gastric cancer mouse models.
STEMCELL Technologies 5-Azacytidine, Size: 50 mg
5-Azacytidine is an analog of the nucleoside cytidine which can be incorporated into DNA and RNA. 5-Azacytidine acts as an epigenetic modifier by incorporating into DNA where it irreversibly binds to DNA methyltransferases, thus inhibiting their activity. REPROGRAMMING· Increases reprogramming efficiency of mouse fibroblasts to induced pluripotent stem (iPS) cells by inducing full reprogramming of partially reprogrammed cells (Mikkelsen et al.).· Resets epigenetic memory in mouse iPS cells, in combination with Trichostatin A (Kim et al.). DIFFERENTIATION· Enhances differentiation to cardiomyocytes from human embryonic stem cells (Yoon et al.).CANCER RESEARCH· Wide range of anti-metabolic activities when tested against cultured cancer cells and an effective chemotherapeutic agent for acute myelogenous leukemia
Alkali Scientific Cytidine, 5 Grams
Cytidine is a nucleoside composed of the base cytosine attached to a ribose sugar. It is an important building block of RNA and is widely used in molecular biology for various biochemical assays and applications. This 5g bottle of Cytidine is ideal for use in studies involving RNA synthesis, modification, and degradation. Cytidine plays a crucial role in the formation of nucleotides, which are essential for cellular functions such as DNA and RNA replication. It is used in cell culture, nucleotide labeling, and in the preparation of RNA probes for hybridization assays. Cytidine is also important in research on metabolic pathways related to nucleotide metabolism.
Selleck Chemical LLC Trifluridine (NSC 75520) S1778-50mg
Trifluridine (NSC 529182 NSC 75520 Viroptic Trifluorothymidine TFT) is an anti-herpesvirus antiviral agent by interacting viral DNA replication used primarily on the eye
Selleck Chemical LLC Dapivirine (TMC120) S2914-5mg
Dapivirine (TMC120) is a non-nucleoside inhibitor for HIV reverse transcriptase with IC50 of 24 nM inhibits a broad panel of HIV-1 isolates from different classes inclucing a wide range of NNRTI-resistant isolates Phase 3
Selleck Chemical LLC Fialuridine-E1709-5MG
Fialuridine(FIAU DRG-0098 NSC 678514) is a nucleoside analog with antiviral activity It blocks DNAsynthesis in human cytomegalovirus and hepatitis B as well as herpes simplex
Abcam Cytidine-5'-monophosphate (CMP), Nucleoside monophosphate, 100MG
MW 323.2 g/mol, Purity >95%. Nucleoside monophosphate used as a substrate of uridine monophosphate (UMP)/cytidine monophosphate (CMP) kinase (EC 2.7.4.4) to form CDP which upon phosphorylation to CTP supports DNA and RNA biosynthesis.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC 3'-O-methylcytidine | 20594-00-7 | 98.0% | 257.24 g/mol | C10H15N3O5 | 1 ML
3'-O-Methylcytidine is a cytidine nucleoside analog supplied for research use. It is offered both as a solid and as pre-made stock solutions for biochemical and nucleic acid studies, and is characterized by defined molecular properties and recommended storage conditions.
- Molecular formula C10H15N3O5 and molecular weight 257.24 g/mol.
- Purity: 98.0% as reported by the manufacturer.
- Soluble in DMSO at ≥100 mg/mL (≈388.7 mM), suitable for stock solution preparation.
- Available in small solid quantities and common stock concentrations for immediate use.
- Store solid protected from light at 4°C; in solvent store at -80°C (up to 6 months) or -20°C (up to 1 month).
- Intended for research use only; follow appropriate safety and handling procedures.
Sigma Aldrich Fine Chemicals Biosciences 5-Chloro-2′-deoxyuridine | 50-90-8 | MFCD00006531 | 100 mg
5-Chloro-2′-deoxyuridine | Purity: 98% | Mol Wt: 262.65 | 50-90-8 | MFCD00006531 | 100 mg
Apexbio Technology LLC EZLink NHS-Biotin Kit, 10 reactions. Cas: MFCD: NA. Amine-reactive biotinyltation kit
The EZLink NHS-Biotin Kit contains reagents sufficient for 10 biotin labeling reactions. It is a water-soluble biotin reagent for labeling protein, antibody or other molecules with amidogen (NH2-). The biotin in the kit is sufficient and has been activated for direct use. The whole procedure is simple and quick. Other sizes are available. Please inqury us for quote.
Apexbio Technology LLC EZLink NHS-SS-Biotin Kit, 10 reactions. Cas: MFCD: NA. Amine-reactive biotinyltation kit
The EZLink NHS-SS-Biotin Kit contains reagents sufficient for 10 biotin labeling reactions. It is a water-soluble biotin reagent for labeling protein, antibody or other molecules with amidogen (NH2-). The biotin in the kit is sufficient and has been activated for direct use. The whole procedure is simple and quick. Other sizes are available. Please inqury us for quote.
Medchemexpress LLC Nucleoside-analog-1 | 876707-99-2 | 95.0% | C9H9N5O5 | 2 MG
Nucleoside-Analog-1 is a click chemistry reagent. It contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Contains an azide group
- Can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Compatible with molecules containing alkyne groups
- Can undergo strain-promoted alkyne-azide cycloaddition (SPAAC)
- Compatible with molecules containing DBCO or BCN groups
Medchemexpress LLC 5-Methylcytidine | 2140-61-6 | 99.9% | 257.24 | 50 MG
5-Methylcytidine is a nucleoside compound exhibiting antiviral activity. It is a common DNA modification involved in gene expression regulation, development, and is associated with various diseases, including cancer.
- Exhibits antiviral activity against HSV-1
- Crucial for gene expression regulation
- Important for biological development
- Associated with cancer research
Apexbio Technology LLC N1-Methylpseudo-UTP, 10ul (100 mM). Cas: MFCD: NA.
N1-Methylpseudo-UTP, 10ul (100 mM). N1-Methylpseudouridine-5'-Triphosphate, 1-Methylpseudo-UTP. Formula: C10H17N2O15P3 (free acid). Other sizes are available. Please inqury us for quote.
ABclonal Technology EMB Rabbit pAb
This gene encodes a transmembrane glycoprotein that is a member of the immunoglobulin superfamily. The encoded protein may be involved in cell growth and development by mediating interactions between the cell and extracellular matrix. A pseudogene of this gene is found on chromosome 1.