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NittoPhase HL is a high-loading solid support for therapeutic oligonucleotide synthesis, building on the foundation of the product line which has been in use since 2004. It enables higher synthesis scales per column volume while maintaining superior yields and full-length purity. This product allows for efficiency and cost reduction in oligonucleotide synthesis without compromising quality.
Loading capacity: up to 400 μmol/g for DNA & RNA synthesis.
Synthesis scale: proven performance in commercial production at scales up to 400 mmol.
Manufactured under ISO 9001:2015 guidelines.
Flexible for synthesizing RNA, longmers, and other modified molecules at higher loadings.
Consistent high yields and improved purity profiles across various sequences.
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Alkyne-Modifier Serinol Phosphoramidite, 10-1992-02, C42H55N4O7P, M.W. 758.88, 5' terminus or internal modification, Click Chemistry application, 3 min coupling time, -10 to -30 °C storage
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The 5'-Thiol Modifier C6 S-S CE-Phosphoramidite is a versatile chemical reagent designed for the targeted incorporation of thiol groups into oligonucleotides, which allows for easy post-synthesis modifications. Its unique disulfide bridge and C6 spacer facilitate effective thiol liberation, enhancing conjugation efficiency for various applications including biosensing and microarrays. Unlike other modifiers, it simplifies purification processes, making it suitable for diverse bioconjugation needs.
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The PolyOrg Inc. 5'-Dimethoxytrityl-deoxyThymidine-Long Chain Alkylamine Controlled Pore Glass (DMT-dT-LCAA-CPG) is a specialized solid support essential for high-efficiency solid-phase oligonucleotide synthesis. This controlled pore glass offers a stable platform conducive to optimal reaction conditions and yields. It is engineered to withstand solvents commonly used in synthesis, ensuring reproducibility and reliability in generating DNA oligonucleotides.
Optimized for efficient oligonucleotide synthesis
High surface area enhances coupling efficiency
Uniform 1000 Å pore size maximizes synthesis yields
Excellent stability in various synthesis solvents
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More