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5-Fluorocytidine is a fluorinated cytidine nucleoside analog that inhibits maturation of the 45S ribosomal RNA precursor. It is used in biochemical and cellular research to probe RNA processing and nucleoside metabolism; analytical data and certificates of analysis are available for batch validation.
Inhibits maturation of the 45S ribosomal RNA precursor.
Molecular formula C9H12FN3O5 and molecular weight 261.21 g/mol.
High purity (>99.9%) as supplied; certificate of analysis available.
Analytical data available: COA, HNMR, RP-HPLC.
Storage: 4°C under nitrogen; in solution, -80°C (6 months) or -20°C (1 month).
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MW 323.2 g/mol, Purity >95%. Nucleoside monophosphate used as a substrate of uridine monophosphate (UMP)/cytidine monophosphate (CMP) kinase (EC 2.7.4.4) to form CDP which upon phosphorylation to CTP supports DNA and RNA biosynthesis.
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Nucleoside-Analog-1 is a click chemistry reagent. It contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Contains an azide group
Can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc)
Compatible with molecules containing alkyne groups
Can undergo strain-promoted alkyne-azide cycloaddition (SPAAC)
Compatible with molecules containing DBCO or BCN groups
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5-Methyluridine (m5U) is an RNA modified nucleotide generated by RNA methyltransferases (such as TrmA and RumA). It primarily targets specific uracil sites in RNA molecules like the T arm of tRNA and rRNA. 5-Methyluridine relies on enzyme recognition of RNA secondary/tertiary structures (such as the T loop of tRNA or the specific stem-loop structure of rRNA) and participates in physiological processes such as translation accuracy and ribosome function by stabilizing RNA folding or regulating base pairing.
Generated by RNA methyltransferases (such as TrmA and RumA).
Primarily targets specific uracil sites in RNA molecules like the T arm of tRNA and rRNA.
Participates in physiological processes such as translation accuracy and ribosome function.
Stabilizes RNA folding or regulates base pairing.
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