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5-Azacytidine is an analog of the nucleoside cytidine which can be incorporated into DNA and RNA. 5-Azacytidine acts as an epigenetic modifier by incorporating into DNA where it irreversibly binds to DNA methyltransferases, thus inhibiting their activity. REPROGRAMMING· Increases reprogramming efficiency of mouse fibroblasts to induced pluripotent stem (iPS) cells by inducing full reprogramming of partially reprogrammed cells (Mikkelsen et al.).· Resets epigenetic memory in mouse iPS cells, in combination with Trichostatin A (Kim et al.). DIFFERENTIATION· Enhances differentiation to cardiomyocytes from human embryonic stem cells (Yoon et al.).CANCER RESEARCH· Wide range of anti-metabolic activities when tested against cultured cancer cells and an effective chemotherapeutic agent for acute myelogenous leukemia
Medchemexpress, HY-13465 5mg VCH-916 CAS:1200133-34-1 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Guanosine 5′-(B-thio)diphosphate trilithium salt | Purity: ≥85% | Mol Wt: 477.07 | 97952-36-8 | MFCD00057735 | 5mg
Cytidine 5'-diphosphocholine sodium salt dihydrate ~98%, from yeast, solid | Purity: ~98% | Mol Wt: 546.34 | 33818-15-4 | MFCD00150508 | 1G
50-114-3043 EDU 5-ETHYNYL-2-DEOXYUR 250
50-114-3044 EDU 5-ETHYNYL-2-DEOXYUR 500
Uridine | Purity: ≥99% | MW:244.2 | 58-96-8 | MFCD00006526 | 25g
Adenosine 5-Monophosphate| 5G