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5-Azacytidine is an analog of the nucleoside cytidine which can be incorporated into DNA and RNA. 5-Azacytidine acts as an epigenetic modifier by incorporating into DNA where it irreversibly binds to DNA methyltransferases, thus inhibiting their activity. REPROGRAMMING· Increases reprogramming efficiency of mouse fibroblasts to induced pluripotent stem (iPS) cells by inducing full reprogramming of partially reprogrammed cells (Mikkelsen et al.).· Resets epigenetic memory in mouse iPS cells, in combination with Trichostatin A (Kim et al.). DIFFERENTIATION· Enhances differentiation to cardiomyocytes from human embryonic stem cells (Yoon et al.).CANCER RESEARCH· Wide range of anti-metabolic activities when tested against cultured cancer cells and an effective chemotherapeutic agent for acute myelogenous leukemia
Medchem Express / Xanthosine 5-monophosphate (sodium salt) / 50mg / 642185150 / HY-W008990 / / 25899-70-1 / [null] / 408.170 / C10H11N4Na2O9P
Sugar Modified Nucleoside Triphosphates Other sizes are available. Please inqury us for quote.
Medchem Express / Deoxypseudouridine / 1mg / 446257504 / HY-101970 / / 39967-60-7 / [null] / 228.204 / C9H12N2O5
Broadpharm / 5-O-DMT-N2-Isobutyryl-Guanosine / 5g / 761707755 / BP-58850 / / 81246-83-5 / [null] / 655.708 / C35H37N5O8
Medchem Express / VCH-916 / 5mg / 446262955 / HY-13465 / / 1200133-34-1 / MFCD25541650 / 497.740 / C26H36KNO4S
Medchem Express / Acelarin / 5mg / 446256263 / HY-100885 / / 840506-29-8 / MFCD27987942 / 580.482 / C25H27F2N4O8P
Cytidine 5'-diphosphocholine sodium salt dihydrate ~98%, from yeast, solid | Purity: ~98% | Mol Wt: 546.34 | 33818-15-4 | MFCD00150508 | 1G