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Nucleotides are organic molecules that serve as the monomers or subunits of nucleic acids (like DNA and RNA). The building blocks of nucleic acids nucleotides consist of a nitrogenous base (purine or pyrimidine) a five-carbon sugar (ribose or deoxyribose) and at least one phosphate group. A nucleoside along with a phosphate group yields a nucleotide.
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p-SCN-Bn-NOTA trihydrochloride is a macrocyclic chelator p-SCN-Bn-NOTA trihydrochloride can be covalently coupled to molecules such as peptides through the thiocyanate group to form hexacoordinate copper (such as 64Cu) complexes p-SCN-Bn-NOTA trihydrochloride specifically binds to GRPR or EGFR highly expressed on the surface of tumor cells mediating tumor enrichment of radioactive probes p-SCN-Bn-NOTA trihydrochloride can be used to study malignant tumors expressing GRPR or EGFR such as prostate cancer and colorectal cancer[1][2]
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