Cayman Chemical 3 5-dIOA-dC 10mg
A cyclic di-GMP ligand; assembles with cyclic di-GMP to form supramolecular nanoparticles and has been used to deliver cyclic di-GMP in vitro and in vivo; intravenous administration of nanoparticles composed of 3′,5′-diOA-dC and cyclic di-GMP decrease tumor weight and volume, increase the number of CD8+ T cells , neutrophils, and NK cells in the tumor microenvironment, and increase tumoral levels of TNF-α and IFN-γ in a B16/F10 murine melanoma model