Nucleic Acid Synthesis
Medchemexpress LLC 2'-O-Methyluridine | 2140-76-3 | 99.8% | 258.23 | 5 G
2'-O-Methyluridine is a modified nucleoside that can be found in *T. thermophile* tRNA. Its level in serum is decreased in patients with breast cancer. It can be incorporated into siRNA targeting the gene encoding apolipoprotein B, which decreases ApoB protein levels in HepG2 and prevents IFN-α production in isolated human PBMCs.
- Found in *T. thermophile* tRNA
- Decreased serum levels in breast cancer patients
- Can be incorporated into siRNA
- Decreases ApoB protein levels in HepG2
- Prevents IFN-α production in isolated human PBMCs
Selleck Chemical LLC 2-Deoxy-5-Fluorocytidine S2477-5mg
2 -Deoxy-5-fluorocytidine (5-fluoro-2( )-deoxycytidine FCdR) a pyrimidine analog is a DNA methyltransferase (DMNT) inhibitor currently in clinical trials for solid tumors
Cambridge Isotope Laboratories 2'-DEOXYADENOSINE PHOSPHORAMIDITE (15N5, 98%) 95% CHEMICAL PURITY, 10 MG
2'-DEOXYADENOSINE PHOSPHORAMIDITE (15N5, 98%) 95% CHEMICAL PURITY, 10 MG
Cambridge Isotope Laboratories THYMIDINE PHOSPHORAMIDITE (15N2, 96-98%) 95% CHEMICAL PURITY, 10 MG
THYMIDINE PHOSPHORAMIDITE (15N2, 96-98%) 95% CHEMICAL PURITY, 10 MG
Cayman Chemical Bz-IEGR-pNAacetate 5mg
A colorimetric Factor Xa substrate; cleavage of the IEGR peptide sequence releases pNA, which can be quantified by colorimetric detection at 405 nm as a measure of Factor Xa activity
Glen Research Bz-A-LA-CE Phosphoramidite, 10-2000-10E, Locked Nucleic Acid (LNA), 2' O-methylene linkage, 885.96 g/mol, Anhydrous Acetonitrile, Freezer storage -10 to -30°C, Stability 2-3 days
Bz-A-LA-CE Phosphoramidite, 10-2000-10E, Locked Nucleic Acid (LNA), 2' O-methylene linkage, 885.96 g/mol, Anhydrous Acetonitrile, Freezer storage -10 to -30°C, Stability 2-3 days
Medchemexpress LLC 3-Methylcytidine | 2140-64-9 | 99.3% | 257.24 | 50 MG
3-Methylcytidine is a urinary nucleoside that can be used as a biomarker for four different types of cancer: lung cancer, gastric cancer, colon cancer, and breast cancer.
- Utility as a biomarker for detecting lung, gastric, colon, and breast cancers.
Cayman Chemical GDP-L-Fucose Synthasehumn100ug
Source: Recombinant N-terminal histidine-tagged GDP-L-fucose synthase purified from E. coli • Amino acids: 2-321 • MW: 37.98 kDa
Medchemexpress LLC Trifluridine/tipiracil hydrochloride mixture | 733030-01-8 | 99.98% | 435.76 | 100 MG
Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a potent and orally active nucleoside antitumor agent. It is a 1:0.5 molar mixture of alpha,alpha,alpha-tri-fluorothymidine (FTD) and thymidine phosphorylase inhibitor (TPI). This mixture primarily exhibits its antitumor activity by inhibiting thymidylate synthase (TS) and incorporating into DNA. It prevents body weight loss and reduces relative tumor volume in colorectal cancer and gastric cancer mouse models.
- Potent and orally active nucleoside antitumor agent.
- Composition: 1:0.5 molar mixture of FTD and TPI.
- Mechanism of action: inhibition of thymidylate synthase (TS) and incorporation into DNA.
- Prevents body weight loss and reduces relative tumor volume in colorectal cancer and gastric cancer mice models.