Nucleic Acid Synthesis
Apexbio Technology LLC 4-Thio-UTP 50ul (100 mM)
4-Thio-UTP is a nucleotide triphosphate analog in which the oxygen atom at the 4-position of uracil is substituted by a sulfur atom It can be incorporated into RNA molecules during in vitro transcription reactions producing RNAs containing 4-thiouridine modifications This modification provides unique advantages in studying protein interactions RNA modifications and RNA labeling Due to the presence of the sulfur atom RNA modified with 4-Thio-UTP can form cross-links with proteins upon ultraviolet (UV) irradiation facilitating the study of RNA-protein interactions Additionally 4-Thio-UTP can be employed in research on RNA folding and function as well as in studying the cellular localization and roles of RNA
Medchemexpress LLC 2'-O-Methylcytidine | 2140-72-9 | 99.71% | 257.25 | 100 MG
2'-O-Methylcytidine is an orally active 2'-substituted nucleoside that acts as an inhibitor of HCV replication with antiviral activity. It inhibits RNA-dependent RNA polymerase (NS5B)-catalyzed RNA synthesis in vitro by competing with substrate nucleoside triphosphate. The compound has shown antiviral activity against Hepatitis C virus infected human Huh7 AVA5 cells with an EC50 of 1.8 μM, and cytotoxicity against the same cells with a CC50 of >300 μM. In HBI10A cells, 2'-O-Methylcytidine inhibits HCV RNA replication with an IC50 value of 21 μM. Furthermore, in vivo studies demonstrated that 2'-O-Methylcytidine (16.6 mg/kg, p.o., daily for 7 days) reduced serum HCV RNA by 1.05 log10 copies/mL in chronically infected chimpanzees.
- Orally active 2'-substituted nucleoside.
- Inhibits HCV replication.
- Exhibits antiviral activity.
- Competitively inhibits RNA-dependent RNA polymerase (NS5B)-catalyzed RNA synthesis in vitro.
Medchemexpress LLC Acyclovir triphosphate sodium | 221119-43-3 | MFCD09970911 | 99.7% | C8H14N5O12P3.xNa | 5 MG
Acyclovir triphosphate sodium is the sodium salt of acyclovir's active triphosphate metabolite, supplied as a high-purity nucleotide analog for biochemical research. It acts as a chain-terminating inhibitor of viral polymerases and is used in enzymatic assays and nucleic acid studies.
- High purity (HPLC 99.7%).
- Molecular formula C8H14N5O12P3·xNa.
- Functions as a nucleotide analog and polymerase inhibitor.
- Provided in research-scale quantities and solution formats (e.g., 5 mg; 100 mM in water).
- Intended for biochemical assays, polymerase inhibition studies, and nucleic acid research.
- Typically stored frozen at -20 °C per supplier guidance.
Biotium Toxins Receptor Probes Cell and Organelle Stains Cytoskeletal Stains ActinBrite 645 665 1/EA
ActinBrite 645/665 High Affinity Phalloidin Conjugate is a novel far-red fluorescent phalloidin designed to preserve binding affinity for F-actin resulting in bright staining that can be imaged more than one month after staining with minimal loss of signal or specificity 50 U trial size
![eMolecules Medchem Express / Xanthosine 5-monophosphate (sodium salt) / 50mg / 642185150 / HY-W008990 / / 25899-70-1 / [null] / 408.170 / C10H11N4Na2O9P](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502453981.PNG-250.jpg)
eMolecules Medchem Express / Xanthosine 5-monophosphate (sodium salt) / 50mg / 642185150 / HY-W008990 / / 25899-70-1 / [null] / 408.170 / C10H11N4Na2O9P
Medchem Express / Xanthosine 5-monophosphate (sodium salt) / 50mg / 642185150 / HY-W008990 / / 25899-70-1 / [null] / 408.170 / C10H11N4Na2O9P
Cambridge Isotope Laboratories Uridine phosphoramidite (U-13C9 98%) CP 95% 50 mg
Uridine phosphoramidite (U-13C9 98%) CP 95% 50 mg
Medchemexpress LLC NS-102 100mg | 136623-01-3 | 100 MG
NS-102 is a selective kainate (GluK2) receptor antagonist and a potent GluR6/7 receptor antagonist used in neuroscience research. It is a small-molecule solid supplied at high purity for in vitro pharmacology and receptor-binding studies.
- Selective kainate (GluK2) receptor antagonist.
- Potent GluR6/7 receptor antagonist.
- CAS 136623-01-3.
- High purity (≈98%).
- Solid form suitable for small-scale research preparations.
- Commonly supplied in milligram-scale quantities (for example, 100 mg).
Biotium Primary Antibody CD9 CD63 CD81 NA ExoBrite 640 660 1/EA
ExoBrite CD9/CD63/CD81 Single-Color Antibody Cocktail (Far-Red) consists of three tetraspanin antibodies in a single tube all conjugated to far-red dye ExoBrite 640 Designed for high coverage EV staining for flow cytometry
Chem-Impex International, Inc. 2'-Deoxy-L-thymidine | MFCD02683612 | 1G
2'-Deoxy-L-thymidine, MFCD02683612, 1G
Apexbio Technology LLC Pseudo-UTP, 10ul (100 mM). Cas: MFCD: NA.
Pseudo-UTP, 10ul (100 mM). Pseudouridine-5'-Triphosphate, 5-Ribosyl Uracil. Formula: C9H15N2O15P3 (free acid). Other sizes are available. Please inqury us for quote.
Medchemexpress LLC Cytidine-5'-triphosphate-13C,d1 (dilithium) | 97.1% | 497.02 | 1 MG
Cytidine-5'-triphosphate-13C,d1 (Cytidine triphosphate-13C,d1 dilithium; 5'-CTP-13C,d1) dilithium is a deuterium and 13C-labeled version of Cytidine-5'-triphosphate (HY-125818). Cytidine 5′-triphosphate (Cytidine triphosphate; 5'-CTP) is a nucleoside triphosphate that functions as a building block for nucleotides, nucleic acids, and in lipid biosynthesis. Cytidine triphosphate synthase facilitates the conversion of uridine 5′-triphosphate (UTP) to cytidine 5′-triphosphate. This biomolecule is crucial in the de novo pyrimidine biosynthetic pathway in *T. gondii*.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements are incorporated into drug molecules for quantitation during drug development.
- Deuteration can potentially influence the pharmacokinetic and metabolic profiles of drugs.