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Nucleotides are composed of a nitrogenous base covalently bound to a 5-carbon sugar molecule and one or more phosphate functional groups. They are the molecules that make up the structural units of DNA and RNA.
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N1-Methylpseudo-UTP D3 is a chemically modified nucleotide analog labeled with deuterium It is designed to substitute conventional uridine triphosphate during enzymatic transcription reactions allowing for the synthesis of isotope-labeled RNA N1-Methylpseudo-UTP D3 exerts its function through incorporation into RNA thereby conferring distinct structural and biochemical properties to RNA transcripts Based on these properties N1-Methylpseudo-UTP D3 holds research potential in structural analyses of RNA RNA-protein interaction studies and biophysical investigations including nuclear magnetic resonance (NMR) spectroscopy
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An AMPK activator; activates AMPK in a cell-free assay from 1-500 µM; inhibits lipolysis and lipogenesis in primary rat adipocytes from 100-500 µM; increases insulin sensitivity and prevents pancreatic β-cell damage in Zucker diabetic fatty rats at 0.5 mg/kg; induces cardiac mobilization and myofibroblast differentiation of endogenous CD44+CD45-/- MSCs, as well as decreases cardiac scar formation, in an aged mouse model of LAD occlusion-induced myocardial infarction at 0.5 mg/kg
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Aminoallyl-dUTP-X-Cy5 is a fluorescently labeled deoxynucleotide analogue structurally resembling natural thymidine triphosphate (dTTP) It serves as a substrate suitable for enzymatic incorporation into DNA strands through methods such as PCR reverse transcription nick translation or random priming Upon incorporation this molecule confers red fluorescence (excitation/emission 650/665 nm) to nucleic acid probes facilitating their detection in applications including in situ hybridization microarray assays blotting procedures and multiplex fluorescence analyses
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5-FAM-Alkyne is an alkyne-functionalized fluorescein derivative supplied as a solid fluorescent labeling reagent for copper-catalyzed click chemistry. It is designed for conjugation to biomolecules and use in fluorescence-based detection and imaging applications, providing reliable labeling in typical biochemical workflows.
Alkyne functional group for click chemistry.
High purity (95.0%).
Solid form, yellow to brown.
Molecular weight 413.38 g/mol.
Suitable for fluorescent labeling and imaging applications.
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dATP PCR Grade is a 100 mM clear colorless SOLUTIONon of the sodium salt (pH 8.3). PCR Grade nucleotides from Roche are specially manufactured and purified to the highest possible chemical purity. PCR Grade nucleotides contain at least 99% of the relevant deoxynucleoside-triphosphate (dNTP) and less than 0.9% deoxynucleoside-diphosphate (dNDP).
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