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Nucleotides are composed of a nitrogenous base covalently bound to a 5-carbon sugar molecule and one or more phosphate functional groups. They are the molecules that make up the structural units of DNA and RNA.
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N1-Methylpseudo-UTP, 10ul (100 mM). N1-Methylpseudouridine-5'-Triphosphate, 1-Methylpseudo-UTP. Formula: C10H17N2O15P3 (free acid). Other sizes are available. Please inqury us for quote.
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7-deaza-dGTP (7-deaza-2-deoxyguanosine 5-triphosphate) contains a 5 mM solution of 7-deaza-dGTP as a dilithium salt. Nucleotide concentration is determined by measurements of absorbance at 257 nm. Supplied in: Milli-Q water as a lithium salt at (pH 7.0).
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An AMPK activator; activates AMPK in a cell-free assay from 1-500 µM; inhibits lipolysis and lipogenesis in primary rat adipocytes from 100-500 µM; increases insulin sensitivity and prevents pancreatic β-cell damage in Zucker diabetic fatty rats at 0.5 mg/kg; induces cardiac mobilization and myofibroblast differentiation of endogenous CD44+CD45-/- MSCs, as well as decreases cardiac scar formation, in an aged mouse model of LAD occlusion-induced myocardial infarction at 0.5 mg/kg
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dATP PCR Grade is a 100 mM clear colorless SOLUTIONon of the sodium salt (pH 8.3). PCR Grade nucleotides from Roche are specially manufactured and purified to the highest possible chemical purity. PCR Grade nucleotides contain at least 99% of the relevant deoxynucleoside-triphosphate (dNTP) and less than 0.9% deoxynucleoside-diphosphate (dNDP).
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5-Methoxy-UTP is a modified uridine triphosphate nucleotide bearing a methoxy group at the carbon-5 position This modification significantly alters the chemical properties and biological functions of the nucleotide During in vitro mRNA synthesis 5-Methoxy-UTP can be incorporated into RNA molecules generating RNAs containing 5-methoxyuridine residues Methoxy-modified RNA plays an important role in studies focusing on RNA structure function and interactions with proteins Additionally 5-Methoxy-UTP markedly improves RNA stability and protects against intracellular degradation Therefore this modification is widely utilized in gene expression research RNA drug development and gene therapy applications
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