Choose the brand aligned with your industry so we can best serve your needs.
For researchers, scientists, and technical professionals: Your one-stop shop for the complete range of laboratory, production, and safety products and services.
Nucleotides are composed of a nitrogenous base covalently bound to a 5-carbon sugar molecule and one or more phosphate functional groups. They are the molecules that make up the structural units of DNA and RNA.
MW 275.3 g/mol, Purity >95%. Derivatizing agent for detection of carboxylic acid and carbonylated molecules such as lipid peroxidation products (LPP). Has also been used for fluorescence detection of monoterpene alcohols.
MW 407.19 g/mol, Purity >98%. Ribonucleoside monophosphate which upon phosphorylation to GTP becomes incorporated into ribonucleic acids (RNAs) by various RNA polymerase(s). Can be used to study modulation of glutamatergic neurotransmission.
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex. Complexes including the encoded protein may also play a role in late endosome maturation. Mutations in this gene are a cause of type 2E pseudohypoaldosteronism. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
An a-glucosidase inhibitor (IC50 0.7 Ug/ml) and a prodrug form of castanospermine reduces BVDV levels in a plaque formation assay (IC50 16 mM) and increases survival of MDBK infected with BVDV (IC50 47 UM) reduces viremia and increases survival of mice infected with a lethal dose of dengue virus at 50 mg/kg twice daily i.p.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
5-Br-UTP is a chemically modified ribonucleoside triphosphate that incorporates a bromine substituent at the 5 position of uracil Upon enzymatic incorporation into RNA sequences this compound confers enhanced structural stability and tolerance to enzymatic degradation by nucleases Such modified ribonucleotides are frequently employed in SELEX (Systematic Evolution of Ligands by EXponential enrichment) methodologies to generate aptamers exhibiting improved resistance to nucleolytic cleavage and greater thermal robustness Consequently 5-Br-UTP holds relevance for RNA-based therapeutic research and aptamer engineering applications
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Aminoallyl-dUTP-X-Cy5 is a fluorescently labeled deoxynucleotide analogue structurally resembling natural thymidine triphosphate (dTTP) It serves as a substrate suitable for enzymatic incorporation into DNA strands through methods such as PCR reverse transcription nick translation or random priming Upon incorporation this molecule confers red fluorescence (excitation/emission 650/665 nm) to nucleic acid probes facilitating their detection in applications including in situ hybridization microarray assays blotting procedures and multiplex fluorescence analyses
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Cy3-dUTP can be used for direct enzymatic labeling of DNA/cDNA by PCR with Taq polymerase, Nick Translation with DNAse I/ DNA Polymerase I, cDNA labeling and 3-end labeling Other sizes are available. Please inqury us for quote.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
2'-Deoxyadenosine-5'-triphosphate (dATP) trisodium is a nucleotide used in cells for DNA synthesis (or replication), as a substrate of DNA polymerase. It is promising for research of genetic immunodeficiency diseases adenosine deaminase deficiency and purine nucleotide phosphorylase deficiency.
Used as a nucleotide for DNA synthesis (replication).
Substrate of DNA polymerase.
Promising for research in genetic immunodeficiency diseases (adenosine deaminase deficiency and purine nucleotide phosphorylase deficiency).
Induces cytochrome C release in mouse liver mitochondria (0.5 mM; 0-10 min).
Stimulates bacterial biofilm formation in vitro and bacterial adherence to human epithelial cells (400 μM, 16 h).
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
MW 368.15 g/mol, Purity >98%. Nucleotide that is a major component of ribonucleic acid. It is found in dietary supplements as well as natural RNA rich foods and has been shown to increase cognitive function in animals.
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
A nucleoside analog with diverse biological activities; active against S. faecalis (IC50 = 0.02 µM); cytotoxic to P388 and A549 cells (IC50s = 0.008 and 0.019 UG/ml, respectively); reduces infection of Calu-3 cells by SARS-CoV-2 (EC50 = 0.05 µM) but is toxic to A549-ACE2 and Vero cells; increases survival in a mouse model of schistosomiasis when used at 5 mg/kg in combination with NBMPR-P but is toxic and induces mortality when administered alone at the same dose for four days
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More