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Nucleotides are composed of a nitrogenous base covalently bound to a 5-carbon sugar molecule and one or more phosphate functional groups. They are the molecules that make up the structural units of DNA and RNA.
MW 242.23 Da, Purity >98%. Pyrimidine deoxynucleoside. Potent thymidine kinase substrate (IC₅₀ = 16 nM). Pairs with deoxyadenosine in double-stranded DNA. Synchronizes cells in S phase in vivo. .
MW 242.23 Da, Purity >98%. Pyrimidine deoxynucleoside. Potent thymidine kinase substrate (IC₅₀ = 16 nM). Pairs with deoxyadenosine in double-stranded DNA. Synchronizes cells in S phase in vivo. .
MW 354.1 Da, Purity >98%. Selective cytotoxic cell-permeable anti-herpesvirus agent (IC₅₀ = 4.3 μM). Radiosensitizing. Incorporates into DNA increases susceptibility of cancer cell to radiation damage. Active in vivo. .