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Nucleotides are composed of a nitrogenous base covalently bound to a 5-carbon sugar molecule and one or more phosphate functional groups. They are the molecules that make up the structural units of DNA and RNA.
An ionizable cationic lipid LNPs containing IZ-chol can be complexed with DNA with the plasmid-binding efficacy dependent in part on the type of helper lipids in the LNP formulation
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N1-Methylpseudo-UTP, 10ul (100 mM). N1-Methylpseudouridine-5'-Triphosphate, 1-Methylpseudo-UTP. Formula: C10H17N2O15P3 (free acid). Other sizes are available. Please inqury us for quote.
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FITC-labeled ODN 2395 (sodium) is a C class oligodeoxynucleotide that acts as a TLR9 agonist. It is intended for research use only and should not be sold to patients. This product is ideal for evaluating CpG ODN cellular uptake and localization studies.
Can be used to evaluate CpG ODN cellular uptake and localization
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
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7-Deaza-7-Propargylamino-dATP is a chemically modified nucleotide analog derived from deoxyadenosine triphosphate It is designed to enable enzymatic incorporation by DNA polymerases during DNA synthesis thereby facilitating site-specific labeling of DNA 7-Deaza-7-Propargylamino-dATP exerts its biological activity primarily through incorporation into nascent DNA strands introducing a terminal propargyl group that serves as a reactive alkyne handle for conjugation reactions via click chemistry approaches Based on these pharmacological properties 7-Deaza-7-Propargylamino-dATP holds research potential in DNA labeling fluorescent probe generation and studies of DNA polymerase activity specificity and DNA damage detection and repair mechanisms in molecular biology and biomedical research
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Cytidine-5'-triphosphate-15N3 dilithium (5'-CTP-15N3) is 15N labeled Cytidine-5'-triphosphate. It is a nucleoside triphosphate that serves as a building block for nucleotides and nucleic acids, and lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). This compound is an essential biomolecule in the de novo pyrimidine biosynthetic pathway in *T. gondii*.
Can be used as a tracer.
Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Stable heavy isotopes have been incorporated into drug molecules for quantitation during drug development.
Deuteration has potential to affect pharmacokinetic and metabolic profiles of drugs.
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