Molecular Formula C20H22N10O14P2 • 2Na, Purity ≥95%, Formula Weight 734.4, Synonyms: guanylyl-(3'→5')-3'-guanylic acid, cyclic nucleotide, disodium salt, c-di-GMP, Cyclic diguanylate, 3',5'-Cyclic diguanylic acid; A bacterial second messenger and cyclic dinucleotide; an important second messenger in bacteria involved in biofilm formation, motility, virulence, and cell cycling; detected by and binds to STING in eukaryotic cells, activating the innate immune system (Kd = 1.21 M); induces IFN- mRNA expression in vitro (EC50 = 537.8 nM) less potently than other cyclic dinucleotides.