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Antigen: phosphopeptide corresponding to amino acid residues surrounding phospho-Ser218,222 of human MEK1/2 • Host: rabbit • Cross Reactivity: (+) NIH 3T3 cells • Application(s): WB • MEK1 is an integral component of the MAPK cascade that regulates cell growth and differentiation.
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Mito-EGFP mRNA encodes a fusion protein composed of a mitochondrial localization sequence fused with enhanced green fluorescent protein (EGFP) Through fusion of EGFP with a mitochondrial-targeting signal it allows real-time observation of mitochondrial dynamics in living cells aiding in revealing mitochondria s key roles in energy metabolism signal transduction and apoptosis Due to its high fluorescence efficiency and mitochondria-specific localization Mito-EGFP simplifies mitochondrial visualization facilitating a clearer understanding of mitochondrial function and behavior in cells EZ Cap Mito-EGFP Probe mRNA (m1 ) is provided at 1 mg/mL and is specifically optimized for mitochondria-specific expression of green fluorescent protein labeling This mRNA is synthesized through co-transcriptional capping resulting in a Cap 1 structure The incorporation of m1 modifications poly(A) tail significantly enhances mRNA stability and lifetime both in vitro and in vivo
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ARCA Cy5 EGFP mRNA (5-moUTP) can be used to analyze mRNA delivery and translation efficiency Upon transfection of cells with ARCA Cy5 EGFP mRNA (5-moUTP) EGFP (Enhanced Green Fluorescent Protein) is expressed EGFP is a frequently used reporter protein that emits strong and bright green fluorescence upon excitation with an excitation/emission maximum of 488 nm/509 nm respectively This mRNA is labeled with the fluorescent dye Cyanine 5 (Cy5) allowing direct visualization of EGFP mRNA upon excitation at specific wavelengths the excitation and emission maxima for Cy5 are 650 nm and 670 nm respectively Cy5 EGFP mRNA is thus ideally suited for analyzing mRNA delivery and localization independently from translation This product is a synthetic mRNA modified by adding a cap structure at the 5 end (Cap) a poly(A) tail at the 3 end and inclusion of the modified nucleotides 5-moUTP and Cyanine 5-UTP The incorporation ratio of Cyanine 5-UTP to 5-moUTP is 1 3 The cap st
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DSG Crosslinker (disuccinimidyl glutarate) is a homobifunctional N-hydroxysuccinimide (NHS) ester crosslinker used as a cleavable ADC linker for antibody-drug conjugation and for amine-to-amine coupling in bioconjugation workflows.
Homobifunctional NHS ester for amine coupling.
Molecular weight 326.26 g/mol and formula C13H14N2O8.
High purity (98.0%) suitable for research use.
Soluble in DMSO (100 mg/mL) with ultrasonic assistance.
Powder stable at -20°C for extended storage.
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