RNAi and RNA Reagents
HORIZON DISCOVERY BIOSCIENCES LIMITED OTP MSE CAV1 SIRNA SP 5NMOL
NC3800280 OTP MSE CAV1 SIRNA SP 5NMOL
HORIZON DISCOVERY BIOSCIENCES LIMITED OTP MSE ARHGAP26 SIRNA SP 5NMO
NC3800285 OTP MSE ARHGAP26 SIRNA SP 5NMO
HORIZON DISCOVERY BIOSCIENCES LIMITED OTP MSE SEC61A1 SIRNA SP 5NMOL
NC3800288 OTP MSE SEC61A1 SIRNA SP 5NMOL
HORIZON DISCOVERY BIOSCIENCES LIMITED IFNAR1 3454 SIRNA SMART 50NMOL
IFNAR1 (human, Entrez gene 3454) ON-TARGETplus siRNA, SMARTPool, 50nmol
HORIZON DISCOVERY BIOSCIENCES LIMITED ON-TARGETPLUS HU UBB SIRNA
ON-TARGETplus human UBB siRNA smartPool, 5nmol
Genscript Corporation SIRP Fc Chimera Human
Signal regulatory protein alpha (SIRP designated CD172a) is also known as CD172 antigen-like family member A (CD172a) also called SHPS-1 (SHP substrate 1) and previously MyD-1 (Myeloid/Dendritic-1) which is a monomeric about 90kDa type I transmembrane glycoprotein that belongs to the SIRP/SHPS (CD172) family of the immunoglobulin superfamily SIRP is Ubiquitous and highly expressed in brain SIRPA/CD172a is immunoglobulin-like cell surface receptor for CD47 and acts as docking protein and induces translocation of PTPN6 PTPN11 and other binding partners from the cytosol to the plasma membrane SIRPA/SHPS-1 supports adhesion of cerebellar neurons neurite outgrowth and glial cell attachment and may play a key role in intracellular signaling during synaptogenesis and in synaptic function by similarity SIRP recognition of surfactants SP-A and SP-D in the lung can inhibit alveolar macrophage cytokine production
Genscript Corporation CD40/TNFRSF5 hFc Chimera Huma
CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects CD40 molecule is a potential target for cancer immunotherapy There are number of completed and ongoing clinical trials where agonistic anti-CD40 monoclonal antibodies are employed to activate an anti-tumor T cell response via activation of dendritic cells
Trilink Bio Technologies Inc CLEANCAP M6 NLS-CRE MRNA 5X1MG
NC2888891 CLEANCAP M6 NLS-CRE MRNA 5X1MG
BIOHIPPO h/m FASN shRNA Set GFP Puro
h/m FASN shRNA Set (GFP Puro) shRNA lentiviral vector expressing GFP with Puromycin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 (sh-mix) 5x10E6 (scr-mix) transducing units TU Validated h/m FASN shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse fatty acid synthase (FASN) The shRNA has been validated to meet or exceed 70% FASN knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
BIOHIPPO h/m GLUT3 shRNA Set GFP Puro
h/m GLUT3 shRNA Set (GFP Puro) shRNA lentiviral vector expressing GFP with Puromycin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 (sh-mix) 5x10E6 (scr-mix) transducing units TU Validated h/m GLUT3 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse Glucose transporter 3 (GLUT3 GLUT-3 or SLC2A3) The shRNA has been validated to meet or exceed 70% GLUT3 knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
Genscript Corporation NKG2D/CD314 hFc Chimera Flag
NKG2D is a type II transmembrane glycoprotein having an extracellular lectin-like domain This domain lacks the recognizable calcium-binding sites found in true C-type lectins and binds protein rather than carbohydrate ligands Human NKG2D is expressed on CD8 alpha beta T cells gamma T cells NK cells and NKT cells