Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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Quantity
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1,636
Tocris Bioscience™ Saracatinib
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective Src tyrosine kinase family inhibitor; anticancer; antiviral; orally bioavailable
1,637
Tocris Bioscience™ A 410099.1 amide-PEG4-amine
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IAP ligand with PEG linker and terminal amine for onward chemistry
1,638
Tocris Bioscience™ Lenalidomide 4'-alkylC3-azide
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Cereblon ligand with alkyl linker and terminal azide for onward chemistry
1,639
Tocris Bioscience™ MD15
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Negative control for MD13 (Cat. No. 7503)
1,640
Tocris Bioscience™ TGN 020
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Aquaporin 4 (AQP4) channel blocker
| Inhibitors | TGN 020 |
|---|---|
| Product Type | TGN 020 |
| Molecular Weight (g/mol) | 206.22 |
| Purity | >99% |
1,641
Tocris Bioscience™ Thalidomide 4'-oxyacetamide-PEG3-amine
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PROTACs (Proteolysis Targeting Chimeras)
1,642
Tocris Bioscience™ AZ 6102
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Potent TNKS1/2 inhibitor
| Target | Tankyrase Inhibitors |
|---|---|
| CAS | 1645286-75-4 |
| Purity | >98% |
| Chemical Name or Material | rel-2-[4-[6-[(3R,5S)-3,5-Dimethyl-1-piperazinyl]-4-methyl-3-pyridinyl]phenyl]-3,7-dihydro-7-methyl-4H-pyrrolo[2,3-d]pyrimidin-4-one |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C25H28N6O |
| Formula Weight | 428.53 |
1,643
Tocris Bioscience™ 2-BFI hydrochloride
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 89196-95-2 Molecular Formula: C11H11ClN2O
| CAS | 89196-95-2 |
|---|---|
| Molecular Formula | C11H11ClN2O |
1,644
Tocris Bioscience™ Rotenone
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CAS: 83-79-4 Molecular Formula: C23H22O6
| CAS | 83-79-4 |
|---|---|
| Molecular Formula | C23H22O6 |
1,645
Tocris Bioscience™ PJ 34 hydrochloride
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CAS: 344458-15-7 Molecular Formula: C17H18ClN3O2
| CAS | 344458-15-7 |
|---|---|
| Molecular Formula | C17H18ClN3O2 |
1,646
Tocris Bioscience™ Kaempferol
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Proapoptotic; downregulates PLK1 expression and activates mitochondrial Ca2+ uniporter
1,647
Tocris Bioscience™ PSB 603
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CAS: 1092351-10-4 Molecular Formula: C24H23ClN6O4S
| CAS | 1092351-10-4 |
|---|---|
| Molecular Formula | C24H23ClN6O4S |
1,648
Tocris Bioscience™ PDD 00017273
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Potent and selective poly (ADP ribose) glycohydrolase (PARG) inhibitor
1,649
Tocris Bioscience™ BOP
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Dual α9β1/α4β1 integrin inhibitor; preferentially mobilizes HSCs
| CAS | 1947348-42-6 |
|---|---|
| Product Type | Inhibitor |
| Color | White |
| Solubility | Soluble to 100mM in water and to 100mM in DMSO |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C25H28N3O7SNa |
| Formula Weight | 537.56 |
1,650
Tocris Bioscience™ DSP-4
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CAS: 40616-75-9 Molecular Formula: C11H16BrCl2N
| CAS | 40616-75-9 |
|---|---|
| Molecular Formula | C11H16BrCl2N |