Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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226
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226
Tocris Bioscience™ MS 154N
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Negative control for MS 154 (Cat No. 7395)
227
Tocris Bioscience™ dBET6
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Potent and selective (+)-JQ1 based Degrader (PROTAC™) targeting BET bromodomains, active in vivo
228
Tocris Bioscience™ Etomidate
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CAS: 33125-97-2 Molecular Formula: C14H16N2O2
| CAS | 33125-97-2 |
|---|---|
| Molecular Formula | C14H16N2O2 |
229
Tocris Bioscience™ D609
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 83373-60-8 Molecular Formula: C11H18KOS2
| CAS | 83373-60-8 |
|---|---|
| Molecular Formula | C11H18KOS2 |
230
Tocris Bioscience™ JNJ 303
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 878489-28-2 Molecular Formula: C21H29ClN2O4S
| CAS | 878489-28-2 |
|---|---|
| Molecular Formula | C21H29ClN2O4S |
231
Tocris Bioscience™ Thalidomide-4-hydroxyacetate
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Carboxylic acid-functionalized Thalidomide; cereblon ligand for PROTACs
232
Tocris Bioscience™ K 03861
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent CDK2 inhibitor
| Target | Cyclin-dependent Kinase Inhibitors |
|---|---|
| CAS | 853299-07-7 |
| Purity | 0.98 |
| Chemical Name or Material | N-[4-[(2-Amino-4-pyrimidinyl)oxy]phenyl]-N'-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]urea |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C24H26F3N7O2 |
233
Tocris Bioscience™ FzM1.8
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Frizzled 4 allosteric agonist; exhibits biased siginaling; preserves stemness
| CAS | 2204290-85-5 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 3-Hydroxy-5-[[(2-Naphthalenylamino)carbonyl]amino]benzoic acid |
| Molecular Formula | C18H14N2O4 |
234
Tocris Bioscience™ SL 0101-1
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 77307-50-7 Molecular Formula: C25H24O12
| CAS | 77307-50-7 |
|---|---|
| Molecular Formula | C25H24O12 |
235
Tocris Bioscience™ Cariporide
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Selective NHE1 inhibitor; cardioprotective and antitumor
| Inhibitors | Cariporide |
|---|---|
| Product Type | Cariporide |
| Molecular Weight (g/mol) | 283.35 |
| Purity | >99% |
236
Tocris Bioscience™ Quizartinib
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Highly potent FLT3 inhibitor
| Product Type | Inhibitor |
|---|---|
| Purity | 98% |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C29H32N6O4S |
| Formula Weight | 560.67 |
237
Tocris Bioscience™ Perifosine
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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PKB/Akt inhibitor; also modulates Kv2.1 current
| CAS | 157716-52-4 |
|---|---|
| Product Type | Bioactive Small Molecule |
| Color | White |
| Solubility | Soluble to 100mM in water and to 100mM in ethanol |
| Purity | >98% |
| Physical Form | Solid |
| Chemical Name or Material | Perifosine |
| Recommended Storage | Store at -20°C |
| Synonym | Octadecyl-(1,1-dimethyl-4-piperidylio) phosphate |
| Molecular Formula | C25H52NO4P |
| Formula Weight | 461.66 |
238
Tocris Bioscience™ Thalidomide 4'-ether-PEG5-amine
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Thalidomide-PEG5-ethylamine
239
Tocris Bioscience™ CST 530, Phenol
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Functionalized IAP ligand for PROTACs™
240
Tocris Bioscience™ WAY 170523
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Greener Choice
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CAS: 307002-73-9 Molecular Formula: C33H31N3O7S
| CAS | 307002-73-9 |
|---|---|
| Molecular Formula | C33H31N3O7S |