Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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226
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240
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60,522
results
226
R&D Systems™ UoS 12258
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Positive allosteric modulator of AMPA receptors (pEC50 = 5.2 for potentiation of AMPA-mediated currents in vitro)
| CAS | 875927-64-3 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | N-[(2S)-5-(6-Fluoro-3-pyridinyl)-2,3-dihydro-1H-inden-2-yl]-2-propanesulfonamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C17H19FN2O2S |
| Formula Weight | 334.41 |
227
R&D Systems™ BromoTag™ cis-AGB1
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Negative control for BromoTag AGB1 (Cat.No. 7686)
228
R&D Systems™ Silodosin
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Selective α1A adrenoceptor antagonist (Ki = 0.036 nM)
| CAS | 160970-54-7 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 2,3-Dihydro-1-(3-hydroxypropyl)-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]-1H-indole-7-carboxamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C25H32F3N3O4 |
| Formula Weight | 495.53 |
229
| Shipping Condition | No special requirements |
|---|---|
| CAS | 64461-82-1 |
| Color | White to Yellow to Light-brown |
| Solubility | Soluble aqueous solution |
| Purity | ≥97.5% |
| Physical Form | Powder |
| Health Hazard 1 | Exclamation mark |
| Chemical Name or Material | Tizanidine hydrochloride |
| Recommended Storage | Normal conditions |
| Synonym | 5-Chloro-4-[(4,5-dihydro-1 H-imidazol-2-yl)amino]-2,1,3-benzothiadiazole hydrochloride |
| Molecular Formula | C9 H8 Cl N5 S . H Cl |
| Melting Point | 280°C |
| Product Line | Life science |
230
R&D Systems™ AP 14145 hydrochloride
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Negative allosteric modulator of KCa2 (SK) channels
231
Thermo Scientific Chemicals Ligustrazine hydrochloride
CAS: 76494-51-4 Molecular Formula: C8H12N2·HCl
| CAS | 76494-51-4 |
|---|---|
| Molecular Formula | C8H12N2·HCl |
232
R&D Systems™ NS 3728
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. VRAC blocker
| Target | Other Chloride Channel Blockers |
|---|---|
| CAS | 265646-85-3 |
| Purity | 0.98 |
| Chemical Name or Material | N-[3,5-bis(Trifluoromethyl)phenyl]-N'-[4-bromo-2-(2 H-tetrazol-5-yl)phenyl]urea |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C16H9BrF6N6O |
233
R&D Systems™ Thalidomide 4'-oxyacetamide-alkylC8-amine
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Cereblon ligand with alkyl linker and terminal amine for onward chemistry
234
R&D Systems™ FTBMT
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Potent and selective GPR52 agonist; orally bioavailable and BBB permeable
| CAS | 1358575-02-6 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 4-[3-[[3-Fluoro-5-(trifluoromethyl)phenyl]methyl]-5-methyl-1H-1,2,4-triazol-1-yl]-2-methylbenzamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C19H16F4N4O |
| Formula Weight | 392.35 |
235
R&D Systems™ VH 032 amide-PEG1-amine
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. VH 032-PEG1-amine
236
R&D Systems™ MR 24
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Potent and selective MST3 kinase binding inhibitor
| Target | Other Kinase Inhibitors |
|---|---|
| Purity | 0.98 |
| Chemical Name or Material | 8-(4-Aminobutyl)-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(1,3-dihydroxypropan-2-ylamino)pyrido[2,3-d]pyrimidin-7-one trihydrochloride |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C26H29ClN6O3.3HCl |
237
R&D Systems™ GLPG 0187
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Potent αv integrin inhibitor
| Target | Integrin Receptor Inhibitors |
|---|---|
| CAS | 1320346-97-1 |
| Purity | 0.97 |
| Chemical Name or Material | 3-[[2,5-Dimethyl-6-[4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)-1-piperidinyl]-4-pyrimidinyl]amino]-N-[(4-methoxyphenyl)sulfonyl]-L-alanine |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C29H37N7O5S |
238
R&D Systems™ Janelia Fluor 526, SE
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Fluorogenic yellow dye; for SMLSM; λabsλem 526/550 nm
239
R&D Systems™ TL 0259
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Selective and highly potent Fgr and Lyn kinase inhibitor; orally bioavailable
| Purity | 98% |
|---|---|
| Chemical Name or Material | 3-[(6,7-Dimethoxy-4-quinazolinyl)oxy]-N-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-4-methylbenzamide dihydrochloride |
| Molecular Formula | C32H34F3N5O4.2HCl |
