Bioactive Small Molecules
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Filtered Search Results
Apexbio Technology LLC GNE-7883-10MG
GNE-7883 (CAS No 2648450-42-2) is a novel compound in the category of targeted cancer therapeutics It originates from advanced pharmaceutical research focused on inhibiting specific molecular pathways involved in tumor growth The mechanism of action primarily involves the blockade of key signaling pathways which are crucial for cancer cell proliferation and survival In vitro studies suggest that GNE-7883 exhibits potent inhibition in the nanomolar to low micromolar range indicating significant efficacy across various cancer cell lines This compound is commonly used in preclinical settings including cell models and animal studies to evaluate its potential as an anticancer agent It also plays a critical role in drug screening processes aimed at identifying new therapeutic candidates Experimental concentrations for GNE-7883 typically depend on the specific research design allowing for flexibility in dosage based on desired outcomes in different experimental setups
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Apexbio Technology LLC GSK8612-100MG
GSK8612 (CAS No 2361659-62-1) is a selective inhibitor commonly studied within the biomedical research community Originating from glucocorticoid receptor modulation research its primary mechanism of action involves targeting the BET (bromodomain and extra-terminal) family of proteins which are crucial in regulating gene expression GSK8612 exhibits potent in vitro activity typically within the nanomolar to low micromolar range making it a valuable tool for investigating epigenetic regulation Its research applications often include cell models to study inflammatory responses and diseases such as cancer as well as animal studies to explore therapeutic potential Drug screening projects frequently incorporate GSK8612 to identify novel treatments that leverage its pathway modulation Experimental concentrations typically depend on the specific research design highlighting its adaptability and importance in developing targeted therapies
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Medchemexpress LLC BI-3802 10MM/1ML
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BI-3802 10MM/1ML
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Medchemexpress LLC AZELASTINE 10 mg
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AZELASTINE 10MG
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Medchemexpress LLC CYP1A1 INHIBITOR 8A 5 mg
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CYP1A1 INHIBITOR 8A 5MG
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Medchemexpress LLC B-RAF IN 1 10 mg
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B-RAF IN 1 10MG
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Medchemexpress LLC STING AGONIST-45 10MM/1ML
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STING AGONIST-45 10MM/1ML
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Cayman Chemical SRS11-92, Purity: ≥98%, CAS: 1467047-25-1, 5 mg
A ferroptosis inhibitor and a derivative of ferrostatin-1; inhibits ferroptotic cell death induced by erastin in HT-1080 human fibrosarcoma cells (EC50 = 6 nM); inhibits iron-induced cell death in isolated mouse kidney proximal tubules at 2 µM; protects rat oligodendrocytes from cystine deprivation-induced cell death in an in vitro model of periventricular leukomalacia at 100 nM; increases survival of medium spiny neurons in rat corticostriatal brain slices in an in vitro model of Huntington’s disease; increases production of ROS in L. major promastigotes at 3 µM; is toxic to L. major promastigotes (LD50 = 3.34 µM)
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Cayman Chemical Galactosylsphingosine (d18:1), Purity: ≥95%, CAS: 2238-90-6, 5 mg
A bioactive sphingolipid; potentiates LPS-induced production of inflammatory cytokines, decreases the mitochondrial membrane potential, and induces cell death in mouse astrocytes; induces demyelination of mouse cerebellar slices at 0.1 and 1 µM; inhibits PDGF-induced translocation of PKC to the cell surface and induces apoptosis in MO3.13 oligodendrocytes; inhibits PPARα-mediated gene transcription in C6 glial cells at 10 and 15 µM; levels are increased in postmortem brain from patients with Krabbe disease
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Medchemexpress LLC DIVARASIB / GDC-6036 10MG
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Divarasib (GDC-6036) is an orally bioavailable, highly potent, and selective KRAS G12C inhibitor with an IC50 of <0.01 μM. Divarasib covalently binds to the switch II (SW-II) pocket of KRAS G12C and irreversibly locks it in the inactive GDP-bound state.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000293566 SERPIN A1B MOUSE H 50UG
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Medchemexpress LLC Cytidine 5′-(tetrahydrogen triphosphate), 2′-deoxy-, sodium salt (1:2) | 102783-51-7 | 99.0% | 511.12 | 50 MG
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Deoxycytidine triphosphate (dCTP) disodium is a nucleoside triphosphate that contains the pyrimidine base cytosine. It is intended for research use only.
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- 10 mg
- 25 mg
- 50 mg
- 100 mg
- 200 mg
- 500 mg
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000293598 FGF-1 CANINE 2UG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000293601 FGFR-4 MOUSE HEK29 100UG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000294051 ULBP4/RAET1E HUMAN 10UG
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