Crosslinking Reagents
Sigma Organic Chemistry Cellulose Acetate Butyrate | 1EA
Cellulose Acetate Butyrate, 1EA
About This Item:
UNSPSC Code: 12352100
Storage: room temp
Sigma Organic Chemistry Cellulose Acetate Butyrate | 5EA
Cellulose Acetate Butyrate, 5EA
About This Item:
UNSPSC Code: 12352100
Storage: room temp
TARGETMOL CHEMICALS INC SULFO-SMCC SODIUM 200MG
Also available in 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Sulfo-SMCC sodium is a commonly used hetero-bifunctional non-cleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups respectively. purity: 99%
Cayman Chemical EvernIc AcId 50mg
An activator of the HIF signaling pathway as demonstrated by HRE reporter assay (EC50 1.2 UM) HIF-1a nuclear translocation assay (EC50 1.3 UM) and increased VEGF expression (EC50 1.6 UM) activity is blocked by excess iron suggesting that ML-228 can chelate iron
Cayman Chemical Clobetasol PropIonate 10g
A small molecule that at 1-25 UM improves ER protein-folding ability stimulates the expression of multiple chaperone proteins and induces phosphorylation of eIF2a to reduce protein synthesis exerts antidiabetic activity in both ob/ob and diet-induced obese mice at 150 mg/kg improving insulin sensitivity and glucose homeostasis as well as protecting pancreatic B cells against ER stress
Cayman Chemical TazarotenIc AcId 50mg
A synthetic peptide (PKTPKKAKKL) corresponding to a sequence of histone H1 phosphorylated by Cdk5 with a Km value of 5 UM
Cayman Chemical CDDO methyl ester 50mg
Antigen phosphopeptide corresponding to amino acid residues surrounding phospho-Thr386 of human MEK 1 expected to react with bovine canine chicken mouse non-human primates and Xenopus MEK1 Host rabbit Cross Reactivity ( ) rat MEK1 Application(s) WB MEK1 is an integral component of the MAPK cascade that regulates cell growth and differentiation MEK1 is phosphorylated by MAPK on Thr292 and Thr386
Cayman Chemical DIsuccInImIdyl Glutarate 5mg
A selective ligand for the lipid-binding protein NUCB1 blocking binding of the probe arachidonoyl ethanolamide-diazirine with an IC50 value of 3 3 UM
Cayman Chemical HomogentIsIc AcId 50mg
A potent synthetic agonist of GPR55 (EC50 0 26 UM) does not act at the related kynurenic acid receptor GPR35 and is a weak antagonist of CB1 and CB2 (IC50s 21 8 and 15 1 UM respectively)
Cayman Chemical FlutIcason PropIonate 10mg
A substrate of IMPDH a NAD -dependent enzyme that generates xanthosine monophosphate in a rate-limiting step in DNA RNA and glycoprotein synthesis also involved in potentiating the umami taste sensation
Cayman Chemical DIsuccInImIdyl Glutarate 50mg
A dual inhibitor of EGFR and HER2 (IC50s 92 and 59 nM respectively) selective for EGFR and HER2 over a panel of 12 kinases (IC50s 5000 nM) but does inhibit VEGFR2 and Src (IC50s 800 and 1400 nM respectively) inhibits the proliferation of NCI H508 colorectal cancer cells expressing wild-type or mutant forms of HER2 (IC50s 0 2-3 nM) reduces tumor growth in BT474 breast and SKOV3 ovarian cancer mouse xenograft models at 40 mg/kg
Cayman Chemical N-Hydroxysulfosuccinimide so
A topically-active imidazole antifungal compound that has broad spectrum activity in vitro against dermatophytes molds yeasts dimorphic fungi and some Gram-positive bacteria a potent inhibitor of cytochrome P450 aromatase (Ki 68 nM IC50 270 nM)