Protein Modification Reagents
Medchemexpress LLC Thiol-PEG2-t-butyl ester | 1398044-50-2 | MFCD22574781 | 96.0% | 250.35 g·mol-1 | C11H22O4S | 5 MG
Thiol-PEG2-t-butyl ester is a short polyethylene glycol (PEG2) linker bearing a tert-butyl-protected thiol, designed for use in the synthesis of proteolysis-targeting chimeras (PROTACs). It provides a hydrophilic spacer and a masked thiol functionality for selective deprotection and conjugation in medicinal chemistry workflows.
- Provides a short PEG2 spacer to improve solubility and flexibility.
- Contains a tert-butyl-protected thiol for masked thiol chemistry.
- Suitable for incorporation into bifunctional PROTAC molecules.
- Available in research-scale pack sizes for synthetic work.
- Molecular weight ~250.35 g·mol-1 and formula C11H22O4S.
eMolecules 882847-34-9 | Fmoc-NH-PEG6-CH2CH2COOH | Ambeed | MFCD06656474 | 575.655 | C30H41NO10 | 95.000 | OC(=O)CCOCCOCCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 5g | 552715488
Fmoc-NH-PEG6-CH2CH2COOH | Ambeed | 882847-34-9 | MFCD06656474 | 575.655 | C30H41NO10 | 95.000 | OC(=O)CCOCCOCCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 5g | 552715488
Medchemexpress LLC Tos-PEG3-CH2COOH | 1581248-63-6 | 98.0% | 362.4 g·mol⁻¹ | C15H22O8S | 5 MG
Tos-PEG3-CH2COOH is a polyethylene glycol (PEG)-based linker bearing a tosylated PEG3 spacer and a terminal carboxylic acid group. It is intended for use in medicinal chemistry workflows as a spacer/conjugation handle during the synthesis of proteolysis-targeting chimeras (PROTACs). Consult the manufacturer's certificate of analysis for batch-specific handling and storage instructions.
- Tosylated PEG3 spacer terminating in a carboxylic acid
- Designed for use as a PROTAC linker and conjugation handle
- Molecular weight 362.4 g·mol⁻¹; formula C15H22O8S
- Available in small research pack sizes suitable for synthesis screening
- Reported purity approximately 98% (supplier listing)
- Store under conditions specified in the certificate of analysis
eMolecules 2496687-00-2 | Thalidomide-O-amido-PEG4-propargyl | Broadpharm545.545 | C26H31N3O10 | 93.000 | O=C(COc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12)NCCOCCOCCOCCOCC#C | 100mg | 510428562
Thalidomide-O-amido-PEG4-propargyl | Broadpharm | 2496687-00-2545.545 | C26H31N3O10 | 93.000 | O=C(COc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12)NCCOCCOCCOCCOCC#C | 100mg | 510428562