Protein Modification Reagents
Bioworld D(+) Galactose, 250 g
An monosaccharidic aldo hexose potentially useful in aging studies. Specifications:High Purity GradeSpecific Rotation (2% water): 79 - 81°Appearance: White PowderBoiling Point : 410.8 °CDensity : 1.5 g/cm3HS Code : 29400090Melting Point: 168-170 °CRTECS Number: LW5490000
Medchemexpress LLC Iodoacetamide-PEG5-azide | 98.6% | 474.29 g/mol | C14H27IN4O6 | 5 MG
Iodoacetamide-PEG5-azide is a PEG-based linker and click-chemistry reagent bearing an iodoacetamide and an azide functional group. It is intended for bioconjugation and PROTAC synthesis workflows, enabling selective cysteine modification via the iodoacetamide and subsequent conjugation through azide-alkyne cycloaddition.
- Contains iodoacetamide and azide functional groups.
- PEG5 spacer provides flexible linker length.
- Compatible with copper-catalyzed azide-alkyne cycloaddition (CuAAC).
- Also compatible with strain-promoted alkyne-azide cycloaddition (SPAAC).
- High purity (98.6%) suitable for research applications.
eMolecules N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester | 2093152-78-2 | MFCD30723293 | 500mg
Broadpharm | N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester | 500mg | 340377010 | BP-23468 | 98.000 | 2093152-78-2 | MFCD30723293 | 503.633 | C25H45NO9
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eMolecules tert-Butyl 3-(2-bromoethoxy)propanoate | Acrotein ChemBio Inc. | 1393330-36-3 | MFCD22574803 | 253.136 | C9H17BrO3 | 97.000 | CC(C)(C)OC(=O)CCOCCBr | 5g | 731673479
tert-Butyl 3-(2-bromoethoxy)propanoate | Acrotein ChemBio Inc. | 1393330-36-3 | MFCD22574803 | 253.136 | C9H17BrO3 | 97.000 | CC(C)(C)OC(=O)CCOCCBr | 5g | 731673479
Medchemexpress LLC N3-PEG2-C2-NHS ester | 1312309-64-0 | MFCD20926376 | ≥98.0% | 300.27 | C11H16N4O6 | 250 MG
N3-PEG2-C2-NHS ester is an azide-functionalized PEG2 NHS ester linker used for bioconjugation and the synthesis of antibody-drug conjugates. The molecule contains an NHS ester for coupling to primary amines and an azide group enabling click chemistry (copper-catalyzed azide-alkyne cycloaddition and strain-promoted cycloaddition). It is provided as a high-purity liquid and is soluble in DMSO for research-scale conjugation.
- Azide-functionalized PEG2 linker for click chemistry
- NHS ester for efficient amine coupling
- High purity (≥98.0%) for reliable conjugation
- Soluble in DMSO (approx. 100 mg/mL) for stock solutions
- Stable when stored dry at -20°C for extended periods
Medchemexpress LLC DSPE-PEG-endo-BCN (MW 2000) | 93.3% | 2000 | 5 MG
DSPE-PEG-endo-BCN (MW 2000) is a PEG lipid designed to enhance the delivery efficiency and tissue specificity of poorly soluble drugs. It is suitable for use in drug delivery research.
- Peg lipid
- Can improve delivery efficiency of poorly soluble drugs
- Can improve tissue specificity of poorly soluble drugs
- Suitable for drug delivery research
Cayman Chemical TrImethoprIm-PEG-amIntrIfl 1mg
A conjugated form of trimethoprim linked with polyethylene glycol (PEG) amine
Medchemexpress LLC 5,8,11,14-tetraoxa-2-azahexadecanedioic acid, 1-(1,1-dimethylethyl) ester | 876345-13-0 | MFCD30528568 | ≥97.0% | 351.39 g/mol | C15H29NO8 | 1 G
Boc-NH-PEG4-CH2COOH is a Boc-protected polyethylene glycol (PEG4) linker terminating in a carboxylic acid, used as a cleavable linker in conjugation chemistry and in the synthesis of PROTACs and antibody-drug conjugates.
- Cleavable Boc-protected PEG4 linker suitable for conjugation chemistry.
- Terminal carboxylic acid compatible with amide coupling reactions.
- High purity (≥97.0%) and molecular weight 351.39 g/mol.
- Available as a 1 g unit; other pack sizes are offered for synthetic applications.
- Store pure material at -20°C; stability in solvent is limited and temperature dependent.
Sino Biological Anti-MMAE Antibody, Mouse MAb
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with MMAE conjugated to BSA. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Avanti Polar Lipids DSPE-PEG(5000) Amine | 474922-26-4 | 10mg
DSPE-PEG(5000) Amine | Purity: 99% | Mol Wt: 5900.029 | 474922-26-4 | 10mg
Medchemexpress LLC PEG5-(CH2CO2H)2 | 77855-75-5 | MFCD29079379 | 99.3% | 310.30 | C12H22O9 | 1G
HOOCCH2O-PEG4-CH2COOH is a symmetric PEG-based dicarboxylic acid linker used as a flexible, hydrophilic spacer for the construction of bifunctional degraders and other conjugates. It provides two carboxylic acid termini for standard coupling chemistries, and its PEG4 backbone imparts solubility and conformational flexibility suited for PROTAC and homo-PROTAC synthesis.
- Symmetric PEG4 dicarboxylic acid linker.
- Provides carboxylic acid termini for straightforward coupling reactions.
- PEG backbone increases solubility and flexibility.
- Designed for use in PROTAC and homo-PROTAC synthesis.
- High purity suitable for research applications.
- Typically supplied in small pack sizes for lab-scale synthesis.
Medchemexpress LLC Pomalidomide-PEG3-azide | 2267306-15-8 | MFCD32198606 | 98.9% | 488.45 | C21H24N6O8 | 5 MG
Pomalidomide-PEG3-azide is an E3 ligase ligand-linker conjugate that combines a pomalidomide-derived cereblon ligand with a three-unit polyethylene glycol linker terminated in an azide. It is intended for use in targeted protein degradation workflows and for click-chemistry functionalization to attach pomalidomide-based ligands to alkyne- or strained-alkyne-containing molecules.
- Facilitates PROTAC construction via CRBN-mediated recruitment of E3 ligase.
- Azide terminus enables copper-catalyzed and strain-promoted azide-alkyne cycloadditions.
- PEG3 linker provides flexible spacing between ligand and cargo.
- High reported purity (≈98.9%) supports analytical and synthetic applications.
- Soluble in DMSO at high concentration; store under inert atmosphere at -20°C to preserve stability.
Advanced Biomatrix Extralink PEGDA Thiol-reactive crosslinker for HyStem-C and HyStem-HP, 10 units x 0.5 mL
Extralink PEGDA is a thiol-reactive crosslinker designed for use in HyStem-C and HyStem-HP kits. Pack comes with Buffer B. HyStem V2.0 kit components are reconstituted with a buffered 1X PBS. The resulting components will also result in a pH neutral isotonic salt hydrogel. The ending pH, osmo, and rheological properties are the same from Version 1.0 to Version 2.0. Extralink is polyethylene diacrylate (PEGDA) with a molecular weight of 3500 Da. It is a thiol-reactive crosslinker that covalently reacts with the thiol groups in Glycosil, Heprasil and Gelin-S to form viscoelastic hydrogels. Extralink vials are >80% acrylated and supplied as the crosslinking component in all HyStem hydrogel kits. Extralink vials are paired with HyStem-C and HyStem–HP kits while Extralink-Lite vials are paired with HyStem hydrogel kits to provide comparable experiences despite the different HA concentrations.
Avanti Polar Lipids ALC-0159, PEGylated lipid, 500 mg
ALC-0159 is a PEGylated lipid designed to enhance the stability and biocompatibility of lipid nanoparticle (LNP) drug delivery systems. It significantly improves circulation time and bioavailability for therapeutics by reducing immune recognition, making it a key component in mRNA-based vaccines and other drug delivery applications.
- Enhanced stability and biocompatibility for LNP drug delivery
- Facilitates effective nanoparticle encapsulation and intracellular delivery
- Reduces immune recognition and improves bioavailability
- Essential for mRNA-based vaccines, including COVID-19 formulations
- Applicable in nucleic acid delivery, CRISPR, siRNA, and antisense oligonucleotides
- Soluble in ethanol, DMSO, and specific solvent combinations
- Stored at -20°C and shipped on dry ice
- High purity of over 99% (TLC)
Medchemexpress LLC Biotin-PEG2-Mal | 305372-39-8 | 99.6% | 525.62 | 100 MG
Biotin-PEG2-Mal is a PEG-based PROTAC linker. It can be used in the synthesis of PROTACs, which contain two different ligands connected by a linker. One ligand is for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Used in the synthesis of PROTAC.