Protein Modification Reagents
Medchemexpress LLC Mal-PEG3-NHS ester | 1537892-36-6 | 99.5% | 398.36 g/mol | C17H22N2O9 | 100 MG
Mal-PEG3-NHS ester is a noncleavable antibody-drug conjugate (ADC) linker containing a maleimide group and an N-hydroxysuccinimide (NHS) ester separated by a three-unit polyethylene glycol (PEG3) spacer. It enables conjugation to thiols and primary amines for bioconjugation and ADC synthesis in research applications.
- Provides thiol and amine reactive groups for versatile bioconjugation.
- PEG3 spacer increases aqueous solubility and reduces aggregation.
- High purity suitable for research and conjugation workflows.
- Available in multiple pack sizes for small- to mid-scale synthesis.
- Store protected from light and under inert gas to maintain stability.
Medchemexpress LLC Hs-peg6-ch2ch2-boc | 1818294-40-4 | MFCD26127815 | 95.0% | 426.57 g/mol | C19H38O8S | 5 MG
HS-PEG6-CH2CH2-Boc is a PEG-based linker bearing a thiol terminus and a Boc-protected terminus, designed for use in the synthesis of PROTACs and other bifunctional molecules. It provides a flexible, hydrophilic spacer useful for connecting ligands while maintaining solubility and synthetic handle orthogonality.
- Suitable for use in PROTAC and bifunctional molecule synthesis.
- Thiol terminus enables selective conjugation to thiol-reactive partners.
- PEG6 spacer provides flexibility and improved aqueous solubility.
- Boc-protected terminus allows orthogonal protection and selective deprotection.
- Molecular formula C19H38O8S; molecular weight 426.57 g/mol.
Medchemexpress LLC TCO-PEG4-VC-PAB-MMAE | 2758671-45-1 | 99.3% | 1522.91 | C78H127N11O19 | 10 MG
TCO-PEG4-VC-PAB-MMAE is a drug-linker conjugate intended for use in antibody-drug conjugate (ADC) assembly and click-chemistry bioconjugation workflows. It combines a trans-cyclooctene (TCO) click handle, a PEG4-Val-Cit-PAB cleavable linker, and the cytotoxic payload MMAE to enable site-selective conjugation and intracellular release of the payload.
- Provides a trans-cyclooctene (TCO) handle for inverse electron-demand Diels-Alder reactions with tetrazines.
- Contains a PEG4-Val-Cit-PAB cleavable linker for enzymatic payload release.
- Conjugated to MMAE to supply a potent cytotoxic payload for ADC research.
- High purity (99.3%) suitable for research and bioconjugation workflows.
- Characterized by molecular weight 1522.91 and formula C78H127N11O19.
![eMolecules Broadpharm / 14-(Amine-PEG3-ethylcarbamoyl)tridecanoic t-butyl ester / 100mg / 784455746 / BP-40052 / 95.000 / / [null] / 488.710 / C26H52N2O6](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502473269.JPG-250.jpg)
eMolecules Broadpharm / 14-(Amine-PEG3-ethylcarbamoyl)tridecanoic t-butyl ester / 100mg / 784455746 / BP-40052 / 95.000 / / [null] / 488.710 / C26H52N2O6
Broadpharm / 14-(Amine-PEG3-ethylcarbamoyl)tridecanoic t-butyl ester / 100mg / 784455746 / BP-40052 / 95.000 / / [null] / 488.710 / C26H52N2O6
eMolecules Bromoacetamido-PEG5-Propargyl | 1807521-10-3 | MFCD28064329 | 500mg
Broadpharm | Bromoacetamido-PEG5-Propargyl | 500mg | 550804089 | BP-22203 | 98.000 | 1807521-10-3 | MFCD28064329 | 396.278 | C15H26BrNO6
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Medchemexpress LLC DBCO-PEG4-DBCO | 2182601-68-7 | 97.4% | 810.93 | C48H50N4O8 | 10 MG
DBCO-PEG4-DBCO is a PEG-based bifunctional linker bearing two dibenzocyclooctyne (DBCO) groups. It is used as a click chemistry reagent for strain-promoted alkyne-azide cycloaddition (SPAAC) and as a PEG linker in PROTAC and antibody-drug conjugate (ADC) synthesis.
- Click chemistry reagent enabling SPAAC with azide-functionalized partners.
- Provides a PEG4 spacer to improve solubility and linker flexibility.
- High solubility in DMSO; manufacturer provides in vitro and in vivo formulation protocols.
- Typical purity around 97.4% and appears as a white to yellow solid.
- Suitable for use in PROTAC and ADC synthesis workflows.
![eMolecules Broadpharm / (S)-26-Bis-(m-PEG8)-amidohexanoic acid / 100mg / 445408939 / BP-24221 / / 2353409-77-3 / [null] / 967.110 / C42H82N2O22](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502477246.JPG-250.jpg)
eMolecules Broadpharm / (S)-26-Bis-(m-PEG8)-amidohexanoic acid / 100mg / 445408939 / BP-24221 / / 2353409-77-3 / [null] / 967.110 / C42H82N2O22
Broadpharm / (S)-26-Bis-(m-PEG8)-amidohexanoic acid / 100mg / 445408939 / BP-24221 / / 2353409-77-3 / [null] / 967.110 / C42H82N2O22
eMolecules Mal-PEG6-NHS ester | Broadpharm | 1599472-25-9 | MFCD20926374 | 530.527 | C23H34N2O12 | 98.000 | O=C(CCOCCOCCOCCOCCOCCOCCN1C(=O)C=CC1=O)ON1C(=O)CCC1=O | 250mg | 208572696
Mal-PEG6-NHS ester | Broadpharm | 1599472-25-9 | MFCD20926374 | 530.527 | C23H34N2O12 | 98.000 | O=C(CCOCCOCCOCCOCCOCCOCCN1C(=O)C=CC1=O)ON1C(=O)CCC1=O | 250mg | 208572696
![Carbosynth LLC. Cyclo[Arg-Ala-Asp-D-Tyr-Lys(PEG)], 1mg, MF= C34H54N10O11](https://assets.fishersci.com/TFS-Assets/CCG/product-images/501952424.jpg-250.jpg)
Carbosynth LLC. Cyclo[Arg-Ala-Asp-D-Tyr-Lys(PEG)], 1mg, MF= C34H54N10O11
This item has a minimum order quantity of 3 per supplier requirements
Application: Control peptide for RGD-3000-PI, salt: Trifluoroacetate Salt, one letter code: c[RADyK(PEG)], MW: 778.87
Medchemexpress LLC Amino-PEG4-CH2COOH | 195071-49-9 | >=98.0% | 251.28 g/mol | C10H21NO6 | 100 MG
Amino-PEG4-CH2COOH is a PEG-based bifunctional linker supplied as a purified solid for use in synthetic chemistry. It provides an amino terminus and a terminal carboxylic acid for conjugation and spacer functionality in bifunctional molecules such as PROTACs and antibody-drug conjugates.
- Bifunctional linker with amino and carboxylic acid termini.
- Four-unit polyethylene glycol (PEG4) spacer for flexible linkage.
- High purity suitable for synthesis and research use.
- Low molecular weight and defined formula for analytical consistency.
- Available in small-scale research quantities for lab-scale synthesis.
Medchemexpress LLC Hs-peg-sh (mw 3400) | 97.0% | 100 MG
Hs-peg-sh (mw 3400) is a linear homobifunctional PEG and a cross-linker. It is utilized in drug delivery and for the preparation of PEG hydrogels.
- Linear homobifunctional PEG
- Cross-linker
- Used for drug delivery
- Used for preparation of PEG hydrogels
Cayman Chemical DPPE-MPEG 2000 5mg
A PEGylated form of DPPE; has been used in the synthesis of anionic liposomes for drug redistribution and toxicity prevention
Medchemexpress LLC 5,8,11-trioxa-2-azatetradecanedioic acid, 1-(4-cycloocten-1-yl) ester | 2141981-86-2 | ≥98.0% | 373.44 g/mol | C18H31NO7 | 5 MG
TCO-PEG3-acid is a trans-cyclooctene-functionalized PEG3 carboxylic acid used as a click-chemistry reagent for rapid bioorthogonal conjugation. The TCO moiety undergoes inverse-electron-demand Diels-Alder (iEDDA) reactions with tetrazine derivatives, enabling fast and selective labeling or linker assembly in chemical biology and bioconjugation workflows.
- Provides rapid, bioorthogonal iEDDA conjugation with tetrazine partners.
- Includes a PEG3 spacer to improve solubility and reduce steric hindrance.
- Terminal carboxylic acid enables standard coupling chemistries.
- High solubility in DMSO; ultrasonic assistance may aid dissolution.
- Stable under recommended storage conditions (for example, -20°C for extended storage).
- Suitable for labeling, linker synthesis, and bioconjugation applications.