Protein Modification Reagents

Chemical agents used to modify the amino acid side chains of proteins in order to alter their native charges, block or expose reactive binding sites, inactivate functional groups, and change functional groups to create targets for crosslinking and labeling.

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3,346 – 3,360 of 5,663 results

3,346

Ambeed AMBEED

5000869020 CBZ-NH-PEG2-CH2COOH 1GR

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3,347

Medchemexpress LLC Cl-C6-PEG4-O-CH2COOH (PROTAC Linker 4) | 1799506-30-1 | 98.0% | 370.87 | 50 MG

Cl-C6-PEG4-O-CH2COOH (PROTAC Linker 4) is a PEG-based PROTAC linker used in the synthesis of chloroalkane-containing PROTACs (HaloPROTACs). This product is for research use only. PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins by connecting an E3 ubiquitin ligase ligand and a target protein ligand via a linker.

Appearance: oil
Color: colorless to light yellow
Chemical formula: C16H31ClO7
Shipping: room temperature in continental US
Storage in pure form: -20°C for 3 years, 4°C for 2 years
Storage in solvent: -80°C for 6 months, -20°C for 1 month
Solubility in ethanol: 100 mg/mL (needs ultrasonic)
Solubility in DMSO: 100 mg/mL (needs ultrasonic, use newly opened DMSO)

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3,348

Cayman Chemical dPE-PEG 2000 MaleImIde 25mg

A MDM2-p53 protein-protein interaction inhibitor (IC50 0.21 nM) selectively inhibits the MDM2-p53 protein-protein interaction over MDM4-p53 YAP1-TEAD4 PCSK9-LDLR and Bcl-2-Bak interactions in TR-FRET assays (IC50s 3.3 150 50 and 50 UM respectively) inhibits the growth of SJSA-1 cells (GI50 38 nM) induces apoptosis in SJSA-1 cells at 100 nM induces tumor regression and prevents tumor regrowth in an SJSA-1 rat xenograft model and an HSAX2655 PDX rat liposarcoma model at 27 mg/kg