Protein Modification Reagents

Chemical agents used to modify the amino acid side chains of proteins in order to alter their native charges, block or expose reactive binding sites, inactivate functional groups, and change functional groups to create targets for crosslinking and labeling.

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4,336

Medchemexpress LLC CPTH2-alkyne | 1613116-16-7 | 99.0% | 5 MG

CPTH2-alkyne is an alkyne-tagged analog of CPTH2 that inhibits N-acetyltransferase 10 (NAT10). It accumulates in nucleoli, localizes to the nuclear periphery and cytoplasm, and is supplied as a high-purity research compound for studies of nuclear architecture and laminopathy.

Alkyne-tagged analog suitable for bioorthogonal click chemistry.
Inhibits N-acetyltransferase 10 (NAT10) for epigenetic studies.
Accumulates in nucleoli and localizes to nuclear periphery and cytoplasm.
High purity (99.0%) for research applications.
Stable as a powder at -20°C for up to 3 years.

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4,337

Medchemexpress LLC Cy5-PEG5-azide bromide | 98.8% | C44H63BrN6O6 | 1 MG

Cy5-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a click chemistry reagent containing an Azide group, capable of undergoing copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with Alkyne groups, and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups.

PEG-based PROTAC linker
Used in the synthesis of PROTACs
Click chemistry reagent
Contains an azide group
Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with alkyne groups
Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups