Protein Modification Reagents
Medchemexpress LLC N3-PEG4-C2-NHS ester | 944251-24-5 | 98.9% | 1 G
N3-PEG4-C2-NHS ester is a non-cleavable 4-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). It is a click chemistry reagent containing an azide group, capable of undergoing copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups. It can also participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Non-cleavable 4-unit PEG linker
- Used in the synthesis of antibody-drug conjugates (ADCs)
- Click chemistry reagent
- Contains an azide group
- Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc)
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
Medchemexpress LLC Amino-PEG4-C2-SH (hydrochloride) | 2762393-21-3 | 95.0% | 289.82 | 25 MG
Thiol-PEG4-NH2 hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Used in the synthesis of PROTACs
- PEG-based PROTAC linker
- Exploits intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Molecular Dimensions 50% V/V PEG SMEAR HIGH (250ML)
PEG is an effective crystallization agent due to its protein-protein interaction promoting properties. The BCS Screen overcomes the impracticality of sampling all PEG varieties that has led to a few variants predominating in the most common screens. PEG Smears are designed primarily for efficient screening of chemical space. It is generally thought that well-defined, single PEG species produce the best diffracting crystals. Thus, optimization might involve identifying the single PEG compound that produces the best crystal for structural studies. MOLECULAR DIMENSIONS INC mfg# MD2-250-260
Hampton Research PEG/Ionic Liquid HT 1 ml, Deep Well block format
PEG/Ionic Liquid HT 1 ml, Deep Well block format
Broadpharm DBCO-S-S-PEG3-biotin| 5MG| CAS# 1430408-09-5| MOLWT: 869.1
DBCO-S-S-PEG3-biotin| 5MG| CAS# 1430408-09-5| MOLWT: 869.1
Worthington Biochemical Corporation TPCK TREAT. TRYPSIN 500MG
A chromatographically purified, diafiltered, lyophilized powder that has been treated with L-(tosylamido-2-phenyl) ethyl chloromethyl ketone (TPCK) to inhibit contaminating chymotryptic activity [Kostka and Carpenter, J. Biol. Chem. 239, 1799 (1964)].
ILEX LIFE SCIENCES LLC Cellendes ToLuminate PEG Photogel Photocrosslinkable 1/EA
ToLuminate PEG Photogel Kit photo-crosslinkable hydrogel DESCRIPTION The ToLuminate PEG Photogel Kit manufactured by Cellendes GmbH provides reagents for setting up cell-compatible hydrogels formed by illumination with blue light (365-405 nm) on the basis of the thiol-ene chemistry Its major components are norbornene-modified dextran (N-Dextran) and the thiol-modified cross-linker PEG-Link When the two reagents are combined and illuminated in the presence of LAP (Lithium phenyl-2 4 6-trimethyl benzoyl phosphinate) thiol groups on PEG-Link are activated and form stable thioether bonds with norbornene groups on N-Dextran The components are mixed at physiological pH (pH 7 2) for optimal cell compatibility There is ample time to place the pre-gel solution in any culture dish or container since gelation starts only after illumination Cell adhesion peptides can be covalently attached to N-Dextran to provide a cell-adhesive matrix QUANTITY Up to 4 ml hydrogel
Worthington Biochemical Corporation COLLAGENASE TYPE 4 50 MG
Collagenase, Type 4 (Code: CLS-4), which is filtered through a 0.22 micron membrane and lyophilized in vials.