Protein Modification Reagents
Broadpharm endo-BCN-PEG4-NHS ester, 500 mg, C26H38N2O10, molecular weight 538.6 g/mol, NHS ester, BCN, DMSO/DMF/DCM soluble, amine-reactive, azide-reactive
The endo-BCN-PEG4-NHS ester is a versatile reagent specifically designed for bioconjugation applications, facilitating the labeling of biomolecules such as proteins, peptides, and oligonucleotides. With its unique functional groups, this heterobifunctional PEG derivative offers a reliable method for biomolecule modification through efficient click chemistry. Ideal for research in PROTAC synthesis and various advanced bioconjugation techniques, this product enhances solubility in aqueous environments, ensuring optimal performance in scientific applications.
- NHS ester group enables easy labeling of primary amines.
- BCN moiety allows for rapid, copper-free click reactions.
- PEG4 spacer increases solubility in aqueous media.
- Reagent grade, suitable for research purposes.
- Available quantity: 500 mg.
- Storage conditions at -20°C for stability.
- Applications include PROTAC synthesis and bioconjugation.
Medchemexpress LLC 5,8,11,14,20,23,26,29-Octaoxa-2,17,32-triazatritriacontanedioic acid, 1,33-bis(1,1-dimethylethyl) | 2182601-75-6 | ≥97.0% | C₃₀H₆₁N₃O₁₂ | 250 MG
NH-bis(PEG4-C2-NH-Boc) is a chemical compound, also known by its chemical name 5,8,11,14,20,23,26,29-Octaoxa-2,17,32-triazatritriacontanedioic acid, 1,33-bis(1,1-dimethylethyl) ester. It is identified by CAS number 2182601-75-6 and has a molecular formula of C₃₀H₆₁N₃O₁₂. This product appears as a colorless to light yellow liquid with a purity of ≥97.0%. It is intended for research use only and has not been fully validated for medical applications.
- Identified by CAS number 2182601-75-6
- Molecular formula: C₃₀H₆₁N₃O₁₂
- Molecular weight: 655.82
- Purity: ≥97.0%
- Appearance: Colorless to light yellow liquid
- Storage (pure form): -20°C for 3 years, 4°C for 2 years
- Storage (in solvent): -80°C for 6 months, -20°C for 1 month
- For research use only
Medchemexpress LLC Dbco-peg4-mmaf | 2360411-65-8 | 99.8% | 1266.56 g·mol⁻¹ | C69H99N7O15 | 5 MG
DBCO-PEG4-MMAF is a drug-linker conjugate used in antibody-drug conjugate research. It contains a dibenzocyclooctyne (DBCO) reactive group connected via a four-unit polyethylene glycol (PEG4) linker to the tubulin inhibitor MMAF, enabling strain-promoted alkyne-azide cycloaddition (SPAAC) for bioconjugation.
- Contains DBCO reactive group for SPAAC click chemistry.
- PEG4 spacer provides flexibility and improved solubility.
- Includes MMAF payload, a potent tubulin polymerization inhibitor.
- High purity and provided as a solid, white to off-white powder.
- Available in small research pack sizes suitable for conjugation workflows.
Medchemexpress LLC Mal-amido-PEG6-NHS ester | 1137109-21-7 | 98.76% | 601.60 | 5 G
Mal-amido-PEG6-NHS ester is a PEG-based PROTAC linker. It is for research use only. This chemical can be used in the synthesis of PROTACs, which contain two different ligands connected by a linker. One ligand is for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Contains two different ligands connected by a linker
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
eMolecules LG-PEG10-azide | | | 10mg
Broadpharm | LG-PEG10-azide | 10mg | 445408914 | BP-24243 | | | | 866.909 | C34H66N4O21
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Kyfora Bio Polyethylene glycol 1450
Polyethylene glycol (PEG) is a water-soluble biologically inert polymer that has a number of biological and pharmaceutical applications Specifically PEG1450 can be used as an excipient in pharmaceutical products or as a coating on nanoparticles to prevent opsonization in vivo It can also be used for purification of plasmid DNA The polymer chains are hydroxyl terminated at both ends
Medchemexpress LLC DSPE-PEG-maleimide (MW 3400) ammonium | 474922-22-0 | >95.0% | 3,400 Da | (C2H4O)nC52H93N3NaO13P | 50 MG
DSPE-PEG-maleimide (MW 3400) ammonium is a phospholipid-polyethylene glycol conjugate bearing a terminal maleimide reactive group. Supplied as the ammonium salt with a nominal PEG molecular weight of 3,400 Da, it is used to introduce thiol-reactive functionality into lipid assemblies for site-specific conjugation and formulation of PEGylated lipid nanoparticles and nanostructured lipid carriers.
- Provides maleimide functionality for thiol-specific conjugation.
- Anchors into lipid bilayers via DSPE for stable incorporation into liposomes and nanoparticles.
- PEG chain (3,400 Da) imparts steric stabilization and extended circulation.
- Compatible with thiol-containing ligands for targeted conjugation.
- Typically supplied at ≥95% purity; store under dry and low-temperature conditions.
Medchemexpress LLC Apn-peg5-vc-pab-mmae | 2252392-31-5 | 95.2% | 1577.90 | 1 MG
APN-PEG5-VC-PAB-MMAE is a drug-linker conjugate that is part of INA03, a transferrin-competitive antibody-drug conjugate against CD71. Antibody-drug conjugates (ADCs) are comprised of an antibody to which an ADC cytotoxin is attached through an ADC linker. This product is for research use only.
- Drug-linker conjugate
- Component of INA03, a transferrin-competitive antibody-drug conjugate against CD71
- Used in antibody-drug conjugates (ADCs)
Medchemexpress LLC 3,4-dibromo-mal-peg2-amine TFA | 2296708-07-9 | MFCD31814444 | 98.0% | 500.06 g·mol⁻1 | C12H15Br2F3N2O6 | 5 MG
3,4-Dibromo-Mal-PEG2-amine TFA is a PEG-based PROTAC linker supplied as the trifluoroacetic acid salt. It contains a dibromomaleimide reactive handle and a PEG2 spacer terminating in a primary amine, and is intended for use in assembling bifunctional molecules and conjugation chemistry.
- PEG-based linker with a short PEG2 spacer.
- Dibromomaleimide group for selective thiol conjugation.
- Primary amine terminus supplied as TFA salt for improved stability.
- High purity (≈98%) and supplied as a solid.
- Suitable for PROTAC synthesis and bifunctional small-molecule assembly.
- Available in small pack sizes for research-scale use.
Nanocs Vitamin B12 PEG Biotin, 5000 Da, 5 mg
Vitamin B12 PEG Biotin is one of Nanocs bioactive PEG derivatives that can be used for bioassay development. Vitamin B12, also known as cobalamin or cyanocobalamin, is a water soluble vitamin that is involved in the metabolism of cells in human body. Product Specifications:Form: Solid powderColor: RedSolubility: Soluble in waterFunctional ligand: biotinBinding target: Avidin, streptavidin or neutravidinApplications: Bioassay development
![eMolecules Broadpharm / DSPE-PEG-Amine MW 2000 / 100mg / 627957858 / BP-22722 / / 474922-26-4 / [null] / 915.220 / C47H92N2NaO11P](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502499851.JPG-250.jpg)
eMolecules Broadpharm / DSPE-PEG-Amine MW 2000 / 100mg / 627957858 / BP-22722 / / 474922-26-4 / [null] / 915.220 / C47H92N2NaO11P
Broadpharm / DSPE-PEG-Amine MW 2000 / 100mg / 627957858 / BP-22722 / / 474922-26-4 / [null] / 915.220 / C47H92N2NaO11P
eMolecules Sulfo DBCO-PEG4-amine | Broadpharm | 2055198-05-3 | MFCD30458045 | 674.770 | C32H42N4O10S | 0.000 | NCCOCCOCCOCCOCCC(=O)NCC(C(=O)NCCC(=O)N1Cc2ccccc2C#Cc2ccccc12)S(O)(=O)=O | 25mg | 340377134
Sulfo DBCO-PEG4-amine | Broadpharm | 2055198-05-3 | MFCD30458045 | 674.770 | C32H42N4O10S | 0.000 | NCCOCCOCCOCCOCCC(=O)NCC(C(=O)NCCC(=O)N1Cc2ccccc2C#Cc2ccccc12)S(O)(=O)=O | 25mg | 340377134
Med Vet International Timolol Maleate (Generic Timoptic) Solution, 0.5%, 5mL
VET LICENSE NEEDS TO BE PROVIDED IN 3-4 BUSINESS DAYS OR ORDER WILL BE CANCELLED
Timolol Maleate is a generic version of Timoptic. Ophthalmic Timolol is in a class of medications called beta-blockers. It is an ophthalmic solutions that is used to decrease pressure in the eye.
eMolecules Benzyl-PEG4-CH2CO2tBu | 1443467-88-6 | MFCD28122956 | 1g
Broadpharm | Benzyl-PEG4-CH2CO2tBu | 1g | 254745474 | BP-22262 | 97.000 | 1443467-88-6 | MFCD28122956 | 354.443 | C19H30O6
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