Immunohistochemistry Kits and Reagents
Echelon Biosciences Research Labs GLO-PI(3,4,5)P3 BODIPYFL100ug
BODIPY FL PI(3,4,5)P3 (BODIPY FL Phosphatidylinositol 3,4,5-trisphosphate) is a water soluble analog of PI(3,4,5)P3 (PIP3) labeled with the green fluorophore, Bodipy-FL at the sn-1 position.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3,4,5-trisphosphate (PIP3), formed from PI(4,5)P2 though phosphorylation by PI 3-kinase, activates numerous signaling pathways resulting in cell proliferation, growth, survival, glucose transport and protein synthesis. High PIP3 levels from disregulation of PI3-K have been demonstrated in cancer and inflammatory diseases. PIP3 is hydrolyzed by the phosphatases PTEN to PI(4,5)P2 and SHIP to PI(3,4)P2. This item is non returnable
ABclonal Technology ALDH1A2 Rabbit mAb
This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene.
Enzo Life Sciences HO-1 (human), ELISA kit (1x96wells)
Highly sensitive HO-1 ELISA kit enabling detection of HO-1 in cell lysates and tissue extracts in < 2.5 hours. The HO-1 (human), EIA kit is a colorimetric immunometric enzyme immunoassay kit with results in < 2.5 hours. Absorbance is read at 450 nm. Save time, money, and precious sample with fully quantitative results and increased sensitivity compared to Western blot analysis. Alternative Name: Heme oxygenase 1. Sensitivity: 0.78 ng/ml (range 0.78 - 25 ng/ml). Assay Time: <2.5 hours. Applications: ELISA, Colorimetric detection. Species Reactivity: Human. Contents: Microtiter plate, 5X Extraction reagent, Standard, Sample diluent, Wash buffer concentrate, Antibody, Antibody diluent, HRP Conjugate, Conjugate diluent, TMB Substrate, Stop solution 2
ABclonal Technology EIF3A Rabbit pAb
Enables RNA binding activity. Contributes to translation initiation factor activity. Involved in IRES-dependent viral translational initiation, formation of cytoplasmic translation initiation complex, and viral translational termination-reinitiation. Located in cytosol, nucleolus, and nucleoplasm. Part of eukaryotic translation initiation factor 3 complex.
Medchemexpress LLC METTL1 protein, human (His-tagged) | >95.0% | 50 UG
Recombinant human METTL1 (residues D32-Q265) with an N-terminal His tag, provided as purified protein for biochemical and structural studies. The protein represents the catalytic component of the METTL1-WDR4 methyltransferase complex and is intended for use in enzymology, binding assays, and molecular biology applications.
- Purity greater than 95% as determined by reducing SDS-PAGE.
- Molecular weight approximately 30 kDa.
- N-terminal His tag to facilitate purification and detection.
- Amino acid range D32-Q265 corresponding to the mature catalytic domain.
- Store at -80°C for long-term storage; stable at -20°C up to 3 months; avoid repeated freeze-thaw cycles.
Meso Scale Discovery RPLEX HUM FABP3/HFABP ASYQP
The R-PLEX Human FABP3 (H-FABP) Assay Kit from Meso Scale Diagnostics is used to quantitatively measure human heart-type fatty acid binding protein (H-FABP) in serum plasma cell culture supernatants cell and tissue lysates using an electrochemiluminescent detection technology The assay has high sensitivity and wide dynamic range This multiplex kit includes a 96-well plate coated with capture antibody detection antibody read buffer wash buffer sample diluent calibrator diluent and lyophilized calibrator The assay takes 3 5 hours to complete
OriGene Claudin 4 (CLDN4) CytoSection
Transient overexpression of CLDN4 in HEK293T cells, FFPE control for IHC, ICC and ISH staining, 25 slides per pack
ABclonal Technology MAP2 Rabbit pAb
This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described.
ABclonal Technology γ-Catenin Rabbit pAb
This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene, however, not all transcripts have been fully described.